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Items: 1 to 20 of 103


Munc13 controls the location and efficiency of dense-core vesicle release in neurons.

van de Bospoort R, Farina M, Schmitz SK, de Jong A, de Wit H, Verhage M, Toonen RF.

J Cell Biol. 2012 Dec 10;199(6):883-91. doi: 10.1083/jcb.201208024.


CAPS-1 promotes fusion competence of stationary dense-core vesicles in presynaptic terminals of mammalian neurons.

Farina M, van de Bospoort R, He E, Persoon CM, van Weering JR, Broeke JH, Verhage M, Toonen RF.

Elife. 2015 Feb 26;4. doi: 10.7554/eLife.05438. Erratum in: Elife. 2015;4:e12968.


Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles.

Augustin I, Rosenmund C, Südhof TC, Brose N.

Nature. 1999 Jul 29;400(6743):457-61.


Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming.

Varoqueaux F, Sigler A, Rhee JS, Brose N, Enk C, Reim K, Rosenmund C.

Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):9037-42. Epub 2002 Jun 17.


Munc13-1 is required for the sustained release of insulin from pancreatic beta cells.

Kang L, He Z, Xu P, Fan J, Betz A, Brose N, Xu T.

Cell Metab. 2006 Jun;3(6):463-8. Epub 2006 May 11.


Imaging of evoked dense-core-vesicle exocytosis in hippocampal neurons reveals long latencies and kiss-and-run fusion events.

Xia X, Lessmann V, Martin TF.

J Cell Sci. 2009 Jan 1;122(Pt 1):75-82. doi: 10.1242/jcs.034603. Epub 2008 Dec 9.


A common molecular basis for membrane docking and functional priming of synaptic vesicles.

Siksou L, Varoqueaux F, Pascual O, Triller A, Brose N, Marty S.

Eur J Neurosci. 2009 Jul;30(1):49-56. doi: 10.1111/j.1460-9568.2009.06811.x. Epub 2009 Jun 25.


Aberrant morphology and residual transmitter release at the Munc13-deficient mouse neuromuscular synapse.

Varoqueaux F, Sons MS, Plomp JJ, Brose N.

Mol Cell Biol. 2005 Jul;25(14):5973-84.


Molecular dynamics of a presynaptic active zone protein studied in Munc13-1-enhanced yellow fluorescent protein knock-in mutant mice.

Kalla S, Stern M, Basu J, Varoqueaux F, Reim K, Rosenmund C, Ziv NE, Brose N.

J Neurosci. 2006 Dec 13;26(50):13054-66.


Differential control of vesicle priming and short-term plasticity by Munc13 isoforms.

Rosenmund C, Sigler A, Augustin I, Reim K, Brose N, Rhee JS.

Neuron. 2002 Jan 31;33(3):411-24.


Munc13-independent vesicle priming at mouse photoreceptor ribbon synapses.

Cooper B, Hemmerlein M, Ammermüller J, Imig C, Reim K, Lipstein N, Kalla S, Kawabe H, Brose N, Brandstätter JH, Varoqueaux F.

J Neurosci. 2012 Jun 6;32(23):8040-52. doi: 10.1523/JNEUROSCI.4240-11.2012.


Vesicle capture, not delivery, scales up neuropeptide storage in neuroendocrine terminals.

Bulgari D, Zhou C, Hewes RS, Deitcher DL, Levitan ES.

Proc Natl Acad Sci U S A. 2014 Mar 4;111(9):3597-601. doi: 10.1073/pnas.1322170111. Epub 2014 Feb 18.


CAPS1 deficiency perturbs dense-core vesicle trafficking and Golgi structure and reduces presynaptic release probability in the mouse brain.

Sadakata T, Kakegawa W, Shinoda Y, Hosono M, Katoh-Semba R, Sekine Y, Sato Y, Tanaka M, Iwasato T, Itohara S, Furuyama K, Kawaguchi Y, Ishizaki Y, Yuzaki M, Furuichi T.

J Neurosci. 2013 Oct 30;33(44):17326-34. doi: 10.1523/JNEUROSCI.2777-13.2013.


Cyclin-dependent kinase 5 regulates the polarized trafficking of neuropeptide-containing dense-core vesicles in Caenorhabditis elegans motor neurons.

Goodwin PR, Sasaki JM, Juo P.

J Neurosci. 2012 Jun 13;32(24):8158-72. doi: 10.1523/JNEUROSCI.0251-12.2012.


Synaptic neuropeptide release by dynamin-dependent partial release from circulating vesicles.

Wong MY, Cavolo SL, Levitan ES.

Mol Biol Cell. 2015 Jul 1;26(13):2466-74. doi: 10.1091/mbc.E15-01-0002. Epub 2015 Apr 22.


Nonconserved Ca(2+)/calmodulin binding sites in Munc13s differentially control synaptic short-term plasticity.

Lipstein N, Schaks S, Dimova K, Kalkhof S, Ihling C, Kölbel K, Ashery U, Rhee J, Brose N, Sinz A, Jahn O.

Mol Cell Biol. 2012 Nov;32(22):4628-41. doi: 10.1128/MCB.00933-12. Epub 2012 Sep 10.


Genetic analysis of Mint/X11 proteins: essential presynaptic functions of a neuronal adaptor protein family.

Ho A, Morishita W, Atasoy D, Liu X, Tabuchi K, Hammer RE, Malenka RC, Südhof TC.

J Neurosci. 2006 Dec 13;26(50):13089-101.


RIM1alpha forms a protein scaffold for regulating neurotransmitter release at the active zone.

Schoch S, Castillo PE, Jo T, Mukherjee K, Geppert M, Wang Y, Schmitz F, Malenka RC, Südhof TC.

Nature. 2002 Jan 17;415(6869):321-6.


KIF1A is the primary anterograde motor protein required for the axonal transport of dense-core vesicles in cultured hippocampal neurons.

Lo KY, Kuzmin A, Unger SM, Petersen JD, Silverman MA.

Neurosci Lett. 2011 Mar 24;491(3):168-73. doi: 10.1016/j.neulet.2011.01.018. Epub 2011 Jan 21.


Neurotransmitter release: a docking role for UNC-13 proteins (Commentary on Siksou et al.).

Gundelfinger ED, Fejtová A.

Eur J Neurosci. 2009 Jul;30(1):47-8. doi: 10.1111/j.1460-9568.2009.06832.x. Epub 2009 Jun 25. No abstract available.

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