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Silencing of microRNA-101 prevents IL-1β-induced extracellular matrix degradation in chondrocytes.

Dai L, Zhang X, Hu X, Zhou C, Ao Y.

Arthritis Res Ther. 2012 Dec 10;14(6):R268. doi: 10.1186/ar4114.


MicroRNA-140 is expressed in differentiated human articular chondrocytes and modulates interleukin-1 responses.

Miyaki S, Nakasa T, Otsuki S, Grogan SP, Higashiyama R, Inoue A, Kato Y, Sato T, Lotz MK, Asahara H.

Arthritis Rheum. 2009 Sep;60(9):2723-30. doi: 10.1002/art.24745.


Effect of microRNA-145 on IL-1β-induced cartilage degradation in human chondrocytes.

Yang B, Kang X, Xing Y, Dou C, Kang F, Li J, Quan Y, Dong S.

FEBS Lett. 2014 Jun 27;588(14):2344-52. doi: 10.1016/j.febslet.2014.05.033. Epub 2014 May 27.


MicroRNA-199a* regulates the expression of cyclooxygenase-2 in human chondrocytes.

Akhtar N, Haqqi TM.

Ann Rheum Dis. 2012 Jun;71(6):1073-80. doi: 10.1136/annrheumdis-2011-200519. Epub 2012 Jan 31.


Regulation of human chondrocyte function through direct inhibition of cartilage master regulator SOX9 by microRNA-145 (miRNA-145).

Martinez-Sanchez A, Dudek KA, Murphy CL.

J Biol Chem. 2012 Jan 6;287(2):916-24. doi: 10.1074/jbc.M111.302430. Epub 2011 Nov 18.


MicroRNA-602 and microRNA-608 regulate sonic hedgehog expression via target sites in the coding region in human chondrocytes.

Akhtar N, Makki MS, Haqqi TM.

Arthritis Rheumatol. 2015 Feb;67(2):423-34. doi: 10.1002/art.38952.


MicroRNA-127-5p regulates matrix metalloproteinase 13 expression and interleukin-1β-induced catabolic effects in human chondrocytes.

Park SJ, Cheon EJ, Lee MH, Kim HA.

Arthritis Rheum. 2013 Dec;65(12):3141-52. doi: 10.1002/art.38188. Erratum in: Arthritis Rheum. 2014 May;66(5):1394.


MicroRNA-27b regulates the expression of matrix metalloproteinase 13 in human osteoarthritis chondrocytes.

Akhtar N, Rasheed Z, Ramamurthy S, Anbazhagan AN, Voss FR, Haqqi TM.

Arthritis Rheum. 2010 May;62(5):1361-71. doi: 10.1002/art.27329.


Matrilin-3 induction of IL-1 receptor antagonist is required for up-regulating collagen II and aggrecan and down-regulating ADAMTS-5 gene expression.

Jayasuriya CT, Goldring MB, Terek R, Chen Q.

Arthritis Res Ther. 2012 Sep 11;14(5):R197. doi: 10.1186/ar4033.


Berberine ameliorates cartilage degeneration in interleukin-1β-stimulated rat chondrocytes and in a rat model of osteoarthritis via Akt signalling.

Zhao H, Zhang T, Xia C, Shi L, Wang S, Zheng X, Hu T, Zhang B.

J Cell Mol Med. 2014 Feb;18(2):283-92. doi: 10.1111/jcmm.12186. Epub 2013 Nov 28.


IGF-1 and PDGF-bb suppress IL-1β-induced cartilage degradation through down-regulation of NF-κB signaling: involvement of Src/PI-3K/AKT pathway.

Montaseri A, Busch F, Mobasheri A, Buhrmann C, Aldinger C, Rad JS, Shakibaei M.

PLoS One. 2011;6(12):e28663. doi: 10.1371/journal.pone.0028663. Epub 2011 Dec 14.


MicroRNA-558 regulates the expression of cyclooxygenase-2 and IL-1β-induced catabolic effects in human articular chondrocytes.

Park SJ, Cheon EJ, Kim HA.

Osteoarthritis Cartilage. 2013 Jul;21(7):981-9. doi: 10.1016/j.joca.2013.04.012. Epub 2013 Apr 20.


Modulation of TGF-beta signaling by proinflammatory cytokines in articular chondrocytes.

Roman-Blas JA, Stokes DG, Jimenez SA.

Osteoarthritis Cartilage. 2007 Dec;15(12):1367-77. Epub 2007 Jun 29.


miR-146a, an IL-1β responsive miRNA, induces vascular endothelial growth factor and chondrocyte apoptosis by targeting Smad4.

Li J, Huang J, Dai L, Yu D, Chen Q, Zhang X, Dai K.

Arthritis Res Ther. 2012 Apr 16;14(2):R75. doi: 10.1186/ar3798.


MiR-193b regulates early chondrogenesis by inhibiting the TGF-beta2 signaling pathway.

Hou C, Yang Z, Kang Y, Zhang Z, Fu M, He A, Zhang Z, Liao W.

FEBS Lett. 2015 Apr 13;589(9):1040-7. doi: 10.1016/j.febslet.2015.02.017. Epub 2015 Feb 26.


Low oxygen tension increased fibronectin fragment induced catabolic activities--response prevented with biomechanical signals.

Parker E, Vessillier S, Pingguan-Murphy B, Abas W, Bader DL, Chowdhury TT.

Arthritis Res Ther. 2013 Oct 25;15(5):R163. doi: 10.1186/ar4346.


ECM stiffness primes the TGFβ pathway to promote chondrocyte differentiation.

Allen JL, Cooke ME, Alliston T.

Mol Biol Cell. 2012 Sep;23(18):3731-42. Epub 2012 Jul 25.


Effects and relationship of ERK1 and ERK2 in interleukin-1β-induced alterations in MMP3, MMP13, type II collagen and aggrecan expression in human chondrocytes.

Wang X, Li F, Fan C, Wang C, Ruan H.

Int J Mol Med. 2011 Apr;27(4):583-9. doi: 10.3892/ijmm.2011.611. Epub 2011 Feb 3.


MicroRNA regulation associated chondrogenesis of mouse MSCs grown on polyhydroxyalkanoates.

Yan C, Wang Y, Shen XY, Yang G, Jian J, Wang HS, Chen GQ, Wu Q.

Biomaterials. 2011 Sep;32(27):6435-44. doi: 10.1016/j.biomaterials.2011.05.031. Epub 2011 Jun 12.

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