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Results: 1 to 20 of 138

1.

Synthesis and antitumor activity of novel 2-(1-substituted-piperidin-4-ylamino)quinazolines as antitumor agents.

Wang YK, Jin J, Zhu LN, Zhang Y, Chen XG, Gao XQ, Xu BL.

Yao Xue Xue Bao. 2012 Sep;47(9):1164-78.

PMID:
23227546
[PubMed - indexed for MEDLINE]
2.

Synthesis and antitumor activity of novel quinazoline derivatives containing thiosemicarbazide moiety.

He J, Wang X, Zhao X, Liang Y, He H, Fu L.

Eur J Med Chem. 2012 Aug;54:925-30. doi: 10.1016/j.ejmech.2012.06.003. Epub 2012 Jun 12.

PMID:
22749192
[PubMed - indexed for MEDLINE]
3.

Synthesis and antiparasitic and antitumor activity of 2, 4-diamino-6-(arylmethyl)-5,6,7,8-tetrahydroquinazoline analogues of piritrexim.

Rosowsky A, Papoulis AT, Forsch RA, Queener SF.

J Med Chem. 1999 Mar 25;42(6):1007-17. Erratum in: J Med Chem 2002 Apr 25;45(9):1957.

PMID:
10090784
[PubMed - indexed for MEDLINE]
4.

Design and synthesis of 4,6-substituted-(diaphenylamino)quinazolines as potent EGFR inhibitors with antitumor activity.

Li HQ, Li DD, Lu X, Xu YY, Zhu HL.

Bioorg Med Chem. 2012 Jan 1;20(1):317-23. doi: 10.1016/j.bmc.2011.10.085. Epub 2011 Nov 6.

PMID:
22112541
[PubMed - indexed for MEDLINE]
5.

Synthesis and in vitro antitumor activity of substituted quinazoline and quinoxaline derivatives: search for anticancer agent.

Noolvi MN, Patel HM, Bhardwaj V, Chauhan A.

Eur J Med Chem. 2011 Jun;46(6):2327-46. doi: 10.1016/j.ejmech.2011.03.015. Epub 2011 Mar 15.

PMID:
21458891
[PubMed - indexed for MEDLINE]
6.

Discovery of 6-substituted 4-anilinoquinazolines with dioxygenated rings as novel EGFR tyrosine kinase inhibitors.

Li DD, Fang F, Li JR, Du QR, Sun J, Gong HB, Zhu HL.

Bioorg Med Chem Lett. 2012 Sep 15;22(18):5870-5. doi: 10.1016/j.bmcl.2012.07.079. Epub 2012 Jul 31.

PMID:
22901387
[PubMed - indexed for MEDLINE]
7.

Synthesis and biological evaluation of substituted 6-alkynyl-4-anilinoquinazoline derivatives as potent EGFR inhibitors.

Liu LT, Yuan TT, Liu HH, Chen SF, Wu YT.

Bioorg Med Chem Lett. 2007 Nov 15;17(22):6373-7. Epub 2007 Aug 28.

PMID:
17889528
[PubMed - indexed for MEDLINE]
8.

Discovery of novel 4-anilinoquinazoline derivatives as potent inhibitors of epidermal growth factor receptor with antitumor activity.

Xu YY, Li SN, Yu GJ, Hu QH, Li HQ.

Bioorg Med Chem. 2013 Oct 1;21(19):6084-91. doi: 10.1016/j.bmc.2013.06.070. Epub 2013 Jul 10.

PMID:
23962660
[PubMed - indexed for MEDLINE]
9.

Quinazoline-sulfonamides as potential antitumor agents: synthesis and biological testing.

Alafeefy AM, Alqasoumi SI, Ashour AE, Alshebly MM.

J Enzyme Inhib Med Chem. 2013 Apr;28(2):375-83. doi: 10.3109/14756366.2012.668541. Epub 2012 Apr 2.

PMID:
22468752
[PubMed - indexed for MEDLINE]
10.

Synthesis of substituted benzylamino- and heterocyclylmethylamino carbodithioate derivatives of 4-(3H)-quinazolinone and their cytotoxic activity.

Cao SL, Feng YP, Zheng XL, Jiang YY, Zhang M, Wang Y, Xu M.

Arch Pharm (Weinheim). 2006 May;339(5):250-4.

PMID:
16619282
[PubMed - indexed for MEDLINE]
11.

Synthesis and in vitro antitumour activity evaluation of 1-aryl-1H,3H-thiazolo[4,3-b]quinazolines.

Grasso S, Micale N, Monforte AM, Monforte P, Polimeni S, ZappalĂ  M.

Eur J Med Chem. 2000 Dec;35(12):1115-9.

PMID:
11248410
[PubMed - indexed for MEDLINE]
12.

Design, synthesis and biological evaluation of novel quinazoline derivatives as potential antitumor agents: molecular docking study.

El-Azab AS, Al-Omar MA, Abdel-Aziz AA, Abdel-Aziz NI, el-Sayed MA, Aleisa AM, Sayed-Ahmed MM, Abdel-Hamide SG.

Eur J Med Chem. 2010 Sep;45(9):4188-98. doi: 10.1016/j.ejmech.2010.06.013. Epub 2010 Jun 16.

PMID:
20599299
[PubMed - indexed for MEDLINE]
13.

Substituted quinazolines, part 3. Synthesis, in vitro antitumor activity and molecular modeling study of certain 2-thieno-4(3H)-quinazolinone analogs.

Al-Obaid AM, Abdel-Hamide SG, El-Kashef HA, Abdel-Aziz AA, El-Azab AS, Al-Khamees HA, El-Subbagh HI.

Eur J Med Chem. 2009 Jun;44(6):2379-91. doi: 10.1016/j.ejmech.2008.09.015. Epub 2008 Sep 23.

PMID:
18950904
[PubMed - indexed for MEDLINE]
14.

Substituted quinazolines, part 2. Synthesis and in-vitro anticancer evaluation of new 2-substituted mercapto-3H-quinazoline analogs.

Khalil AA, Abdel-Hamide SG, Al-Obaid AM, El-Subbagh HI.

Arch Pharm (Weinheim). 2003 Apr;336(2):95-103.

PMID:
12761762
[PubMed - indexed for MEDLINE]
15.

Design and synthesis of novel quinazoline nitrogen mustard derivatives as potential therapeutic agents for cancer.

Li S, Wang X, He Y, Zhao M, Chen Y, Xu J, Feng M, Chang J, Ning H, Qi C.

Eur J Med Chem. 2013 Sep;67:293-301. doi: 10.1016/j.ejmech.2013.06.055. Epub 2013 Jul 4.

PMID:
23871909
[PubMed - indexed for MEDLINE]
16.

Synthesis of new 3-(3-phenyl-isoxazol-5-yl) or 3-[(3-phenyl-isoxazol-5-yl)-amino] substituted 4(3H)-quinazolinone derivatives with antineoplastic activity.

Raffa D, Daidone G, Schillaci D, Maggio B, Plescia F.

Pharmazie. 1999 Apr;54(4):251-4.

PMID:
10234736
[PubMed - indexed for MEDLINE]
17.

Synthesis and biological evaluation of novel 2-(2-arylmethylene)hydrazinyl-4-aminoquinazoline derivatives as potent antitumor agents.

Jiang N, Zhai X, Zhao Y, Liu Y, Qi B, Tao H, Gong P.

Eur J Med Chem. 2012 Aug;54:534-41. doi: 10.1016/j.ejmech.2012.05.039. Epub 2012 Jun 7.

PMID:
22727449
[PubMed - indexed for MEDLINE]
18.

[Synthesis and antitumor activity of C3 heterocyclic-substituted fluoroquinolone derivatives (I): ciprofloxacin aminothiodiazole Schiff-bases].

Hu GQ, Wu XK, Wang X, Zhang ZQ, Xie SQ, Huang WL, Zhang HB.

Yao Xue Xue Bao. 2008 Nov;43(11):1112-5. Chinese.

PMID:
19239029
[PubMed - indexed for MEDLINE]
19.

Design, synthesis and biological evaluation of novel quinazoline derivatives as potential anti-cancer agents.

Alafeefy AM, Ashour AE.

J Enzyme Inhib Med Chem. 2012 Aug;27(4):541-5. doi: 10.3109/14756366.2011.601302. Epub 2011 Aug 18.

PMID:
21851213
[PubMed - indexed for MEDLINE]
20.

Quinazoline-tyrphostin as a new class of antitumor agents, molecular properties prediction, synthesis and biological testing.

Alafeefy AM, Alqasoumi SI, Ashour AE, Masand V, Al-Jaber NA, Ben Hadda T, Mohamed MA.

Eur J Med Chem. 2012 Jul;53:133-40. doi: 10.1016/j.ejmech.2012.03.044. Epub 2012 Apr 5.

PMID:
22520152
[PubMed - indexed for MEDLINE]
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