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Results: 1 to 20 of 121

1.

Spontaneous cell fusion of acute leukemia cells and macrophages observed in cells with leukemic potential.

Martin-Padura I, Marighetti P, Gregato G, Agliano A, Malazzi O, Mancuso P, Pruneri G, Viale A, Bertolini F.

Neoplasia. 2012 Nov;14(11):1057-66.

PMID:
23226099
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The AML1-ETO fusion gene and the FLT3 length mutation collaborate in inducing acute leukemia in mice.

Schessl C, Rawat VP, Cusan M, Deshpande A, Kohl TM, Rosten PM, Spiekermann K, Humphries RK, Schnittger S, Kern W, Hiddemann W, Quintanilla-Martinez L, Bohlander SK, Feuring-Buske M, Buske C.

J Clin Invest. 2005 Aug;115(8):2159-68. Epub 2005 Jul 14.

PMID:
16025155
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Upregulation of CD200R1 in lineage-negative leukemic cells is characteristic of AML1-ETO-positive leukemia in mice.

Kagiyama Y, Kitaura J, Togami K, Uchida T, Inoue D, Matsukawa T, Izawa K, Kawabata KC, Komeno Y, Oki T, Nakahara F, Sato K, Aburatani H, Kitamura T.

Int J Hematol. 2012 Nov;96(5):638-48. doi: 10.1007/s12185-012-1207-6. Epub 2012 Oct 25.

PMID:
23097187
[PubMed - indexed for MEDLINE]
4.

Translocation products in acute myeloid leukemia activate the Wnt signaling pathway in hematopoietic cells.

Müller-Tidow C, Steffen B, Cauvet T, Tickenbrock L, Ji P, Diederichs S, Sargin B, Köhler G, Stelljes M, Puccetti E, Ruthardt M, deVos S, Hiebert SW, Koeffler HP, Berdel WE, Serve H.

Mol Cell Biol. 2004 Apr;24(7):2890-904.

PMID:
15024077
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

C-KIT mutation cooperates with full-length AML1-ETO to induce acute myeloid leukemia in mice.

Wang YY, Zhao LJ, Wu CF, Liu P, Shi L, Liang Y, Xiong SM, Mi JQ, Chen Z, Ren R, Chen SJ.

Proc Natl Acad Sci U S A. 2011 Feb 8;108(6):2450-5. doi: 10.1073/pnas.1019625108. Epub 2011 Jan 24.

PMID:
21262832
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

ETO and AML1 phosphoproteins are expressed in CD34+ hematopoietic progenitors: implications for t(8;21) leukemogenesis and monitoring residual disease.

Erickson PF, Dessev G, Lasher RS, Philips G, Robinson M, Drabkin HA.

Blood. 1996 Sep 1;88(5):1813-23.

PMID:
8781439
[PubMed - indexed for MEDLINE]
Free Article
7.

AML1-ETO targets and suppresses cathepsin G, a serine protease, which is able to degrade AML1-ETO in t(8;21) acute myeloid leukemia.

Jin W, Wu K, Li YZ, Yang WT, Zou B, Zhang F, Zhang J, Wang KK.

Oncogene. 2013 Apr 11;32(15):1978-87. doi: 10.1038/onc.2012.204. Epub 2012 May 28.

PMID:
22641217
[PubMed - indexed for MEDLINE]
8.

AML1-ETO rapidly induces acute myeloblastic leukemia in cooperation with the Wilms tumor gene, WT1.

Nishida S, Hosen N, Shirakata T, Kanato K, Yanagihara M, Nakatsuka S, Hoshida Y, Nakazawa T, Harada Y, Tatsumi N, Tsuboi A, Kawakami M, Oka Y, Oji Y, Aozasa K, Kawase I, Sugiyama H.

Blood. 2006 Apr 15;107(8):3303-12. Epub 2005 Dec 27.

PMID:
16380455
[PubMed - indexed for MEDLINE]
Free Article
9.

The AML1 gene: a transcription factor involved in the pathogenesis of myeloid and lymphoid leukemias.

Lo Coco F, Pisegna S, Diverio D.

Haematologica. 1997 May-Jun;82(3):364-70. Review.

PMID:
9234595
[PubMed - indexed for MEDLINE]
Free Article
10.

RUNX1/AML1 DNA-binding domain and ETO/MTG8 NHR2-dimerization domain are critical to AML1-ETO9a leukemogenesis.

Yan M, Ahn EY, Hiebert SW, Zhang DE.

Blood. 2009 Jan 22;113(4):883-6. doi: 10.1182/blood-2008-04-153742. Epub 2008 Nov 25.

PMID:
19036704
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The myeloid master regulator transcription factor PU.1 is inactivated by AML1-ETO in t(8;21) myeloid leukemia.

Vangala RK, Heiss-Neumann MS, Rangatia JS, Singh SM, Schoch C, Tenen DG, Hiddemann W, Behre G.

Blood. 2003 Jan 1;101(1):270-7. Epub 2002 Aug 29.

PMID:
12393465
[PubMed - indexed for MEDLINE]
Free Article
12.

ERG and FLI1 binding sites demarcate targets for aberrant epigenetic regulation by AML1-ETO in acute myeloid leukemia.

Martens JH, Mandoli A, Simmer F, Wierenga BJ, Saeed S, Singh AA, Altucci L, Vellenga E, Stunnenberg HG.

Blood. 2012 Nov 8;120(19):4038-48. doi: 10.1182/blood-2012-05-429050. Epub 2012 Sep 14.

PMID:
22983443
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

AML1-ETO driven acute leukemia: insights into pathogenesis and potential therapeutic approaches.

Hatlen MA, Wang L, Nimer SD.

Front Med. 2012 Sep;6(3):248-62. doi: 10.1007/s11684-012-0206-6. Epub 2012 Aug 9. Review.

PMID:
22875638
[PubMed - indexed for MEDLINE]
14.

The ordered acquisition of Class II and Class I mutations directs formation of human t(8;21) acute myelogenous leukemia stem cell.

Shima T, Miyamoto T, Kikushige Y, Yuda J, Tochigi T, Yoshimoto G, Kato K, Takenaka K, Iwasaki H, Mizuno S, Goto N, Akashi K.

Exp Hematol. 2014 Nov;42(11):955-65.e1-5. doi: 10.1016/j.exphem.2014.07.267. Epub 2014 Aug 4.

PMID:
25101977
[PubMed - indexed for MEDLINE]
15.

ETO, but not leukemogenic fusion protein AML1/ETO, augments RBP-Jkappa/SHARP-mediated repression of notch target genes.

Salat D, Liefke R, Wiedenmann J, Borggrefe T, Oswald F.

Mol Cell Biol. 2008 May;28(10):3502-12. doi: 10.1128/MCB.01966-07. Epub 2008 Mar 10.

PMID:
18332109
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

A histone acetyltransferase p300 inhibitor C646 induces cell cycle arrest and apoptosis selectively in AML1-ETO-positive AML cells.

Gao XN, Lin J, Ning QY, Gao L, Yao YS, Zhou JH, Li YH, Wang LL, Yu L.

PLoS One. 2013;8(2):e55481. doi: 10.1371/journal.pone.0055481. Epub 2013 Feb 4.

PMID:
23390536
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

AML1/ETO proteins control POU4F1/BRN3A expression and function in t(8;21) acute myeloid leukemia.

Dunne J, Gascoyne DM, Lister TA, Brady HJ, Heidenreich O, Young BD.

Cancer Res. 2010 May 15;70(10):3985-95. doi: 10.1158/0008-5472.CAN-09-3604. Epub 2010 May 11.

PMID:
20460523
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Leukemogenic AML1-ETO fusion protein upregulates expression of connexin 43: the role in AML 1-ETO-induced growth arrest in leukemic cells.

Li X, Xu YB, Wang Q, Lu Y, Zheng Y, Wang YC, Lübbert M, Zhao KW, Chen GQ.

J Cell Physiol. 2006 Sep;208(3):594-601.

PMID:
16741927
[PubMed - indexed for MEDLINE]
19.

Hematopoietic stem cell expansion and distinct myeloid developmental abnormalities in a murine model of the AML1-ETO translocation.

de Guzman CG, Warren AJ, Zhang Z, Gartland L, Erickson P, Drabkin H, Hiebert SW, Klug CA.

Mol Cell Biol. 2002 Aug;22(15):5506-17.

PMID:
12101243
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Persistence of multipotent progenitors expressing AML1/ETO transcripts in long-term remission patients with t(8;21) acute myelogenous leukemia.

Miyamoto T, Nagafuji K, Akashi K, Harada M, Kyo T, Akashi T, Takenaka K, Mizuno S, Gondo H, Okamura T, Dohy H, Niho Y.

Blood. 1996 Jun 1;87(11):4789-96.

PMID:
8639850
[PubMed - indexed for MEDLINE]
Free Article
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