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Results: 1 to 20 of 145

1.

Stimulation of the chemosensory TRPA1 cation channel by volatile toxic substances promotes cell survival of small cell lung cancer cells.

Schaefer EA, Stohr S, Meister M, Aigner A, Gudermann T, Buech TR.

Biochem Pharmacol. 2013 Feb 1;85(3):426-38. doi: 10.1016/j.bcp.2012.11.019. Epub 2012 Dec 5.

PMID:
23219522
[PubMed - indexed for MEDLINE]
2.

Functional expression of the transient receptor potential channel TRPA1, a sensor for toxic lung inhalants, in pulmonary epithelial cells.

Büch TR, Schäfer EA, Demmel MT, Boekhoff I, Thiermann H, Gudermann T, Steinritz D, Schmidt A.

Chem Biol Interact. 2013 Dec 5;206(3):462-71. doi: 10.1016/j.cbi.2013.08.012. Epub 2013 Aug 30.

PMID:
23994502
[PubMed - indexed for MEDLINE]
3.

Differentiation dependent expression of TRPA1 and TRPM8 channels in IMR-32 human neuroblastoma cells.

Louhivuori LM, Bart G, Larsson KP, Louhivuori V, Näsman J, Nordström T, Koivisto AP, Akerman KE.

J Cell Physiol. 2009 Oct;221(1):67-74. doi: 10.1002/jcp.21828.

PMID:
19507192
[PubMed - indexed for MEDLINE]
4.

Overexpression of human transient receptor potential M5 upregulates endogenous human transient receptor potential A1 in a stable HEK cell line.

Buber MT, Cerne R, Cortés RY, Bryant RW, Lee SP.

Assay Drug Dev Technol. 2010 Dec;8(6):695-702. doi: 10.1089/adt.2010.0316. Epub 2010 Dec 6.

PMID:
21133676
[PubMed - indexed for MEDLINE]
5.

Expression of functional TRPA1 receptor on human lung fibroblast and epithelial cells.

Mukhopadhyay I, Gomes P, Aranake S, Shetty M, Karnik P, Damle M, Kuruganti S, Thorat S, Khairatkar-Joshi N.

J Recept Signal Transduct Res. 2011 Oct;31(5):350-8. doi: 10.3109/10799893.2011.602413. Epub 2011 Aug 17.

PMID:
21848366
[PubMed - indexed for MEDLINE]
6.

QGP-1 cells release 5-HT via TRPA1 activation; a model of human enterochromaffin cells.

Doihara H, Nozawa K, Kojima R, Kawabata-Shoda E, Yokoyama T, Ito H.

Mol Cell Biochem. 2009 Nov;331(1-2):239-45. doi: 10.1007/s11010-009-0165-7. Epub 2009 Jun 9.

PMID:
19507004
[PubMed - indexed for MEDLINE]
7.

Dynamic changes in the TRPA1 selectivity filter lead to progressive but reversible pore dilation.

Banke TG, Chaplan SR, Wickenden AD.

Am J Physiol Cell Physiol. 2010 Jun;298(6):C1457-68. doi: 10.1152/ajpcell.00489.2009. Epub 2010 Mar 24.

PMID:
20457836
[PubMed - indexed for MEDLINE]
Free Article
8.

Stimulation of human TRPA1 channels by clinical concentrations of the antirheumatic drug auranofin.

Hatano N, Suzuki H, Muraki Y, Muraki K.

Am J Physiol Cell Physiol. 2013 Feb 15;304(4):C354-61. doi: 10.1152/ajpcell.00096.2012. Epub 2012 Dec 5.

PMID:
23220116
[PubMed - indexed for MEDLINE]
Free Article
9.

Enhanced activation of the transient receptor potential channel TRPA1 by ajoene, an allicin derivative.

Yassaka RT, Inagaki H, Fujino T, Nakatani K, Kubo T.

Neurosci Res. 2010 Jan;66(1):99-105. doi: 10.1016/j.neures.2009.09.1712. Epub 2009 Oct 4.

PMID:
19808063
[PubMed - indexed for MEDLINE]
10.

Methylglyoxal activates the human transient receptor potential ankyrin 1 channel.

Ohkawara S, Tanaka-Kagawa T, Furukawa Y, Jinno H.

J Toxicol Sci. 2012;37(4):831-5.

PMID:
22863862
[PubMed - indexed for MEDLINE]
Free Article
11.

Selective blockade of TRPA1 channel attenuates pathological pain without altering noxious cold sensation or body temperature regulation.

Chen J, Joshi SK, DiDomenico S, Perner RJ, Mikusa JP, Gauvin DM, Segreti JA, Han P, Zhang XF, Niforatos W, Bianchi BR, Baker SJ, Zhong C, Simler GH, McDonald HA, Schmidt RG, McGaraughty SP, Chu KL, Faltynek CR, Kort ME, Reilly RM, Kym PR.

Pain. 2011 May;152(5):1165-72. doi: 10.1016/j.pain.2011.01.049. Epub 2011 Mar 12.

PMID:
21402443
[PubMed - indexed for MEDLINE]
12.

The potential role of transient receptor potential type A1 as a mechanoreceptor in human periodontal ligament cells.

Tsutsumi T, Kajiya H, Fukawa T, Sasaki M, Nemoto T, Tsuzuki T, Takahashi Y, Fujii S, Maeda H, Okabe K.

Eur J Oral Sci. 2013 Dec;121(6):538-44. doi: 10.1111/eos.12083. Epub 2013 Aug 31.

PMID:
24206072
[PubMed - indexed for MEDLINE]
13.

Activation of TRPA1 by luminal stimuli induces EP4-mediated anion secretion in human and rat colon.

Kaji I, Yasuoka Y, Karaki S, Kuwahara A.

Am J Physiol Gastrointest Liver Physiol. 2012 Apr;302(7):G690-701. doi: 10.1152/ajpgi.00289.2011. Epub 2011 Dec 29.

PMID:
22207576
[PubMed - indexed for MEDLINE]
Free Article
14.

Molecular cloning and characterization of dog TRPA1 and AITC stimulate the gastrointestinal motility through TRPA1 in conscious dogs.

Doihara H, Nozawa K, Kawabata-Shoda E, Kojima R, Yokoyama T, Ito H.

Eur J Pharmacol. 2009 Sep 1;617(1-3):124-9. doi: 10.1016/j.ejphar.2009.06.038. Epub 2009 Jul 1.

PMID:
19576208
[PubMed - indexed for MEDLINE]
15.

NPPB structure-specifically activates TRPA1 channels.

Liu K, Samuel M, Ho M, Harrison RK, Paslay JW.

Biochem Pharmacol. 2010 Jul 1;80(1):113-21. doi: 10.1016/j.bcp.2010.03.005. Epub 2010 Mar 10.

PMID:
20226176
[PubMed - indexed for MEDLINE]
16.

Inhibition of TRPA1 channel activity in sensory neurons by the glial cell line-derived neurotrophic factor family member, artemin.

Yoshida N, Kobayashi K, Yu L, Wang S, Na R, Yamamoto S, Noguchi K, Dai Y.

Mol Pain. 2011 May 27;7:41. doi: 10.1186/1744-8069-7-41.

PMID:
21619614
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Specific hydroxy fatty acids in royal jelly activate TRPA1.

Terada Y, Narukawa M, Watanabe T.

J Agric Food Chem. 2011 Mar 23;59(6):2627-35. doi: 10.1021/jf1041646. Epub 2011 Feb 24.

PMID:
21348496
[PubMed - indexed for MEDLINE]
18.

TRPA1 is functionally expressed in melanoma cells but is not critical for impaired proliferation caused by allyl isothiocyanate or cinnamaldehyde.

Oehler B, Scholze A, Schaefer M, Hill K.

Naunyn Schmiedebergs Arch Pharmacol. 2012 Jun;385(6):555-63. doi: 10.1007/s00210-012-0747-x. Epub 2012 Mar 18.

PMID:
22426997
[PubMed - indexed for MEDLINE]
19.

Relative contributions of TRPA1 and TRPV1 channels in the activation of vagal bronchopulmonary C-fibres by the endogenous autacoid 4-oxononenal.

Taylor-Clark TE, McAlexander MA, Nassenstein C, Sheardown SA, Wilson S, Thornton J, Carr MJ, Undem BJ.

J Physiol. 2008 Jul 15;586(14):3447-59. doi: 10.1113/jphysiol.2008.153585. Epub 2008 May 22.

PMID:
18499726
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Galangal pungent component, 1'-acetoxychavicol acetate, activates TRPA1.

Narukawa M, Koizumi K, Iwasaki Y, Kubota K, Watanabe T.

Biosci Biotechnol Biochem. 2010;74(8):1694-6. Epub 2010 Aug 7.

PMID:
20699565
[PubMed - indexed for MEDLINE]
Free Article

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