Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 156

1.

A plaque-specific antibody clears existing β-amyloid plaques in Alzheimer's disease mice.

Demattos RB, Lu J, Tang Y, Racke MM, Delong CA, Tzaferis JA, Hole JT, Forster BM, McDonnell PC, Liu F, Kinley RD, Jordan WH, Hutton ML.

Neuron. 2012 Dec 6;76(5):908-20. doi: 10.1016/j.neuron.2012.10.029.

PMID:
23217740
[PubMed - indexed for MEDLINE]
Free Article
2.

An effector-reduced anti-β-amyloid (Aβ) antibody with unique aβ binding properties promotes neuroprotection and glial engulfment of Aβ.

Adolfsson O, Pihlgren M, Toni N, Varisco Y, Buccarello AL, Antoniello K, Lohmann S, Piorkowska K, Gafner V, Atwal JK, Maloney J, Chen M, Gogineni A, Weimer RM, Mortensen DL, Friesenhahn M, Ho C, Paul R, Pfeifer A, Muhs A, Watts RJ.

J Neurosci. 2012 Jul 11;32(28):9677-89. doi: 10.1523/JNEUROSCI.4742-11.2012.

PMID:
22787053
[PubMed - indexed for MEDLINE]
Free Article
3.

Neutralization of soluble, synaptotoxic amyloid β species by antibodies is epitope specific.

Zago W, Buttini M, Comery TA, Nishioka C, Gardai SJ, Seubert P, Games D, Bard F, Schenk D, Kinney GG.

J Neurosci. 2012 Feb 22;32(8):2696-702. doi: 10.1523/JNEUROSCI.1676-11.2012.

PMID:
22357853
[PubMed - indexed for MEDLINE]
Free Article
4.

Passive immunization against pyroglutamate-3 amyloid-β reduces plaque burden in Alzheimer-like transgenic mice: a pilot study.

Frost JL, Liu B, Kleinschmidt M, Schilling S, Demuth HU, Lemere CA.

Neurodegener Dis. 2012;10(1-4):265-70. doi: 10.1159/000335913. Epub 2012 Feb 16.

PMID:
22343072
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Immunization targeting a minor plaque constituent clears β-amyloid and rescues behavioral deficits in an Alzheimer's disease mouse model.

Morales-Corraliza J, Schmidt SD, Mazzella MJ, Berger JD, Wilson DA, Wesson DW, Jucker M, Levy E, Nixon RA, Mathews PM.

Neurobiol Aging. 2013 Jan;34(1):137-45. doi: 10.1016/j.neurobiolaging.2012.04.007. Epub 2012 May 18.

PMID:
22608241
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Sustained levels of antibodies against Aβ in amyloid-rich regions of the CNS following intravenous dosing in human APP transgenic mice.

Bard F, Fox M, Friedrich S, Seubert P, Schenk D, Kinney GG, Yednock T.

Exp Neurol. 2012 Nov;238(1):38-43. doi: 10.1016/j.expneurol.2012.07.022. Epub 2012 Aug 7.

PMID:
22892246
[PubMed - indexed for MEDLINE]
7.

Chronic intranasal treatment with an anti-Aβ(30-42) scFv antibody ameliorates amyloid pathology in a transgenic mouse model of Alzheimer's disease.

Cattepoel S, Hanenberg M, Kulic L, Nitsch RM.

PLoS One. 2011 Apr 5;6(4):e18296. doi: 10.1371/journal.pone.0018296.

PMID:
21483675
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

CD40L disruption enhances Abeta vaccine-mediated reduction of cerebral amyloidosis while minimizing cerebral amyloid angiopathy and inflammation.

Obregon D, Hou H, Bai Y, Nikolic WV, Mori T, Luo D, Zeng J, Ehrhart J, Fernandez F, Morgan D, Giunta B, Town T, Tan J.

Neurobiol Dis. 2008 Feb;29(2):336-53. Epub 2007 Oct 16.

PMID:
18055209
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Limited clearance of pre-existing amyloid plaques after intracerebral injection of Abeta antibodies in two mouse models of Alzheimer disease.

Tucker SM, Borchelt DR, Troncoso JC.

J Neuropathol Exp Neurol. 2008 Jan;67(1):30-40.

PMID:
18091561
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Amelioration of cognitive deficits in plaque-bearing Alzheimer's disease model mice through selective reduction of nascent soluble Aβ42 without affecting other Aβ pools.

Mitani Y, Yarimizu J, Akashiba H, Shitaka Y, Ni K, Matsuoka N.

J Neurochem. 2013 May;125(3):465-72. doi: 10.1111/jnc.12125. Epub 2013 Jan 8.

PMID:
23240999
[PubMed - indexed for MEDLINE]
11.

Robust amyloid clearance in a mouse model of Alzheimer's disease provides novel insights into the mechanism of amyloid-beta immunotherapy.

Wang A, Das P, Switzer RC 3rd, Golde TE, Jankowsky JL.

J Neurosci. 2011 Mar 16;31(11):4124-36. doi: 10.1523/JNEUROSCI.5077-10.2011.

PMID:
21411653
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Stromal cell-derived factor 1α decreases β-amyloid deposition in Alzheimer's disease mouse model.

Wang Q, Xu Y, Chen JC, Qin YY, Liu M, Liu Y, Xie MJ, Yu ZY, Zhu Z, Wang W.

Brain Res. 2012 Jun 12;1459:15-26. doi: 10.1016/j.brainres.2012.04.011. Epub 2012 Apr 17.

PMID:
22560596
[PubMed - indexed for MEDLINE]
13.

Transgenic mice as a model of pre-clinical Alzheimer's disease.

Ferretti MT, Partridge V, Leon WC, Canneva F, Allard S, Arvanitis DN, Vercauteren F, Houle D, Ducatenzeiler A, Klein WL, Glabe CG, Szyf M, Cuello AC.

Curr Alzheimer Res. 2011 Feb;8(1):4-23.

PMID:
21143159
[PubMed - indexed for MEDLINE]
14.

Nitration of tyrosine 10 critically enhances amyloid β aggregation and plaque formation.

Kummer MP, Hermes M, Delekarte A, Hammerschmidt T, Kumar S, Terwel D, Walter J, Pape HC, König S, Roeber S, Jessen F, Klockgether T, Korte M, Heneka MT.

Neuron. 2011 Sep 8;71(5):833-44. doi: 10.1016/j.neuron.2011.07.001.

PMID:
21903077
[PubMed - indexed for MEDLINE]
Free Article
15.

Dynamic analysis of amyloid β-protein in behaving mice reveals opposing changes in ISF versus parenchymal Aβ during age-related plaque formation.

Hong S, Quintero-Monzon O, Ostaszewski BL, Podlisny DR, Cavanaugh WT, Yang T, Holtzman DM, Cirrito JR, Selkoe DJ.

J Neurosci. 2011 Nov 2;31(44):15861-9. doi: 10.1523/JNEUROSCI.3272-11.2011.

PMID:
22049429
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Amyloid-beta levels are significantly reduced and spatial memory defects are rescued in a novel neuroserpin-deficient Alzheimer's disease transgenic mouse model.

Fabbro S, Schaller K, Seeds NW.

J Neurochem. 2011 Sep;118(5):928-38. doi: 10.1111/j.1471-4159.2011.07359.x. Epub 2011 Jul 18.

PMID:
21689108
[PubMed - indexed for MEDLINE]
17.

Antibodies against beta-amyloid reduce Abeta oligomers, glycogen synthase kinase-3beta activation and tau phosphorylation in vivo and in vitro.

Ma QL, Lim GP, Harris-White ME, Yang F, Ambegaokar SS, Ubeda OJ, Glabe CG, Teter B, Frautschy SA, Cole GM.

J Neurosci Res. 2006 Feb 15;83(3):374-84.

PMID:
16385556
[PubMed - indexed for MEDLINE]
18.

Active Aβ vaccination fails to enhance amyloid clearance in a mouse model of Alzheimer's disease with Aβ42-driven pathology.

Nemirovsky A, Shapiro J, Baron R, Kompaniets A, Monsonego A.

J Neuroimmunol. 2012 Jun 15;247(1-2):95-9. doi: 10.1016/j.jneuroim.2012.03.017. Epub 2012 Apr 10.

PMID:
22498096
[PubMed - indexed for MEDLINE]
19.

Immunization with the SDPM1 peptide lowers amyloid plaque burden and improves cognitive function in the APPswePSEN1(A246E) transgenic mouse model of Alzheimer's disease.

Wang CM, Devries S, Camboni M, Glass M, Martin PT.

Neurobiol Dis. 2010 Sep;39(3):409-22. doi: 10.1016/j.nbd.2010.05.013. Epub 2010 May 20.

PMID:
20493257
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Characterizing the appearance and growth of amyloid plaques in APP/PS1 mice.

Yan P, Bero AW, Cirrito JR, Xiao Q, Hu X, Wang Y, Gonzales E, Holtzman DM, Lee JM.

J Neurosci. 2009 Aug 26;29(34):10706-14. doi: 10.1523/JNEUROSCI.2637-09.2009.

PMID:
19710322
[PubMed - indexed for MEDLINE]
Free PMC Article

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk