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Items: 1 to 20 of 119

1.

SnapShot: mTORC1 signaling at the lysosomal surface.

Bar-Peled L, Sabatini DM.

Cell. 2012 Dec 7;151(6):1390-1390.e1. doi: 10.1016/j.cell.2012.11.038. No abstract available.

2.

Disruption of the Rag-Ragulator Complex by c17orf59 Inhibits mTORC1.

Schweitzer LD, Comb WC, Bar-Peled L, Sabatini DM.

Cell Rep. 2015 Sep 1;12(9):1445-55. doi: 10.1016/j.celrep.2015.07.052. Epub 2015 Aug 20.

3.

mTORC1: turning off is just as important as turning on.

Benjamin D, Hall MN.

Cell. 2014 Feb 13;156(4):627-8. doi: 10.1016/j.cell.2014.01.057.

4.

Crosstalk between mTOR complexes.

Xie J, Proud CG.

Nat Cell Biol. 2013 Nov;15(11):1263-5. doi: 10.1038/ncb2877.

PMID:
24189516
5.

dRAGging amino acid-mTORC1 signaling by SH3BP4.

Kim YM, Kim DH.

Mol Cells. 2013 Jan;35(1):1-6. doi: 10.1007/s10059-013-2249-1. Epub 2012 Dec 26. Review.

6.

p18/LAMTOR1: a late endosome/lysosome-specific anchor protein for the mTORC1/MAPK signaling pathway.

Nada S, Mori S, Takahashi Y, Okada M.

Methods Enzymol. 2014;535:249-63. doi: 10.1016/B978-0-12-397925-4.00015-8.

PMID:
24377928
7.

Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids.

Sancak Y, Bar-Peled L, Zoncu R, Markhard AL, Nada S, Sabatini DM.

Cell. 2010 Apr 16;141(2):290-303. doi: 10.1016/j.cell.2010.02.024. Epub 2010 Apr 8.

8.

Amino acids and mTORC1: from lysosomes to disease.

Efeyan A, Zoncu R, Sabatini DM.

Trends Mol Med. 2012 Sep;18(9):524-33. doi: 10.1016/j.molmed.2012.05.007. Epub 2012 Jun 28. Review.

9.

Regulation of mTORC1 by amino acids.

Bar-Peled L, Sabatini DM.

Trends Cell Biol. 2014 Jul;24(7):400-6. doi: 10.1016/j.tcb.2014.03.003. Epub 2014 Mar 31. Review.

10.

Cell signalling: where the mTOR action is.

Wrighton KH.

Nat Rev Mol Cell Biol. 2013 Apr;14(4):191. No abstract available.

PMID:
23847773
11.

Dual specificity kinase DYRK3 couples stress granule condensation/dissolution to mTORC1 signaling.

Wippich F, Bodenmiller B, Trajkovska MG, Wanka S, Aebersold R, Pelkmans L.

Cell. 2013 Feb 14;152(4):791-805. doi: 10.1016/j.cell.2013.01.033.

12.

Metabolism. Differential regulation of mTORC1 by leucine and glutamine.

Jewell JL, Kim YC, Russell RC, Yu FX, Park HW, Plouffe SW, Tagliabracci VS, Guan KL.

Science. 2015 Jan 9;347(6218):194-8. doi: 10.1126/science.1259472. Epub 2015 Jan 7.

13.
14.

RalGAPs regulate mTORC1 signaling.

[No authors listed]

Cancer Discov. 2014 Mar;4(3):OF18. doi: 10.1158/2159-8290.CD-RW2014-011. Epub 2014 Jan 16.

15.

CELL SIGNALING. Seeing mTORC1 specificity.

Buel GR, Blenis J.

Science. 2016 Jan 1;351(6268):25-6. doi: 10.1126/science.aad9696. No abstract available.

PMID:
26721988
16.

The lysosomal v-ATPase-Ragulator complex is a common activator for AMPK and mTORC1, acting as a switch between catabolism and anabolism.

Zhang CS, Jiang B, Li M, Zhu M, Peng Y, Zhang YL, Wu YQ, Li TY, Liang Y, Lu Z, Lian G, Liu Q, Guo H, Yin Z, Ye Z, Han J, Wu JW, Yin H, Lin SY, Lin SC.

Cell Metab. 2014 Sep 2;20(3):526-40. doi: 10.1016/j.cmet.2014.06.014. Epub 2014 Jul 4.

17.

Energy depletion of bovine mammary epithelial cells activates AMPK and suppresses protein synthesis through inhibition of mTORC1 signaling.

Burgos SA, Kim JJ, Dai M, Cant JP.

Horm Metab Res. 2013 Mar;45(3):183-9. doi: 10.1055/s-0032-1323742. Epub 2012 Sep 12.

PMID:
22972179
18.

Leucyl-tRNA synthetase: double duty in amino acid sensing.

Durán RV, Hall MN.

Cell Res. 2012 Aug;22(8):1207-9. doi: 10.1038/cr.2012.68. Epub 2012 Apr 24. Erratum in: Cell Res. 2012 Oct;22(10):1509.

19.

p62 loss reprograms stromal metabolism to promote tumor growth.

[No authors listed]

Cancer Discov. 2014 Sep;4(9):OF17. doi: 10.1158/2159-8290.CD-RW2014-152. Epub 2014 Jul 17.

20.

Beyond indigestion: emerging roles for lysosome-based signaling in human disease.

Ferguson SM.

Curr Opin Cell Biol. 2015 Aug;35:59-68. doi: 10.1016/j.ceb.2015.04.014. Epub 2015 May 15. Review.

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