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Results: 1 to 20 of 129

1.

Combined oral prolonged-release oxycodone and naloxone in chronic pain management.

Mercadante S, Giarratano A.

Expert Opin Investig Drugs. 2013 Jan;22(1):161-6. doi: 10.1517/13543784.2013.752460. Epub 2012 Dec 8. Review.

PMID:
23215628
[PubMed - indexed for MEDLINE]
2.

Analgesic efficacy and safety of oxycodone in combination with naloxone as prolonged release tablets in patients with moderate to severe chronic pain.

Vondrackova D, Leyendecker P, Meissner W, Hopp M, Szombati I, Hermanns K, Ruckes C, Weber S, Grothe B, Fleischer W, Reimer K.

J Pain. 2008 Dec;9(12):1144-54. doi: 10.1016/j.jpain.2008.06.014. Epub 2008 Aug 16.

PMID:
18708300
[PubMed - indexed for MEDLINE]
3.

Single- and multiple-dose pharmacokinetic evaluation of oxycodone and naloxone in an opioid agonist/antagonist prolonged-release combination in healthy adult volunteers.

Smith K, Hopp M, Mundin G, Leyendecker P, Bailey P, Grothe B, Uhl R, Reimer K.

Clin Ther. 2008 Nov;30(11):2051-68. doi: 10.1016/j.clinthera.2008.11.008.

PMID:
19108793
[PubMed - indexed for MEDLINE]
4.

Combined prolonged-release oxycodone and naloxone improves bowel function in patients receiving opioids for moderate-to-severe non-malignant chronic pain: a randomised controlled trial.

Löwenstein O, Leyendecker P, Hopp M, Schutter U, Rogers PD, Uhl R, Bond S, Kremers W, Nichols T, Krain B, Reimer K.

Expert Opin Pharmacother. 2009 Mar;10(4):531-43. doi: 10.1517/14656560902796798 .

PMID:
19243306
[PubMed - indexed for MEDLINE]
5.

Long-term efficacy and safety of combined prolonged-release oxycodone and naloxone in the management of non-cancer chronic pain.

Sandner-Kiesling A, Leyendecker P, Hopp M, Tarau L, Lejcko J, Meissner W, Sevcik P, Hakl M, Hrib R, Uhl R, Dürr H, Reimer K.

Int J Clin Pract. 2010 May;64(6):763-74. doi: 10.1111/j.1742-1241.2010.02360.x. Epub 2010 Mar 29.

PMID:
20370845
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Fixed-ratio combination oxycodone/naloxone compared with oxycodone alone for the relief of opioid-induced constipation in moderate-to-severe noncancer pain.

Simpson K, Leyendecker P, Hopp M, Müller-Lissner S, Löwenstein O, De Andrés J, Troy Ferrarons J, Bosse B, Krain B, Nichols T, Kremers W, Reimer K.

Curr Med Res Opin. 2008 Dec;24(12):3503-12. doi: 10.1185/03007990802584454 .

PMID:
19032132
[PubMed - indexed for MEDLINE]
7.

Bowel function during pain therapy with oxycodone/naloxone prolonged-release tablets in patients with advanced cancer.

Clemens KE, Quednau I, Klaschik E.

Int J Clin Pract. 2011 Apr;65(4):472-8. doi: 10.1111/j.1742-1241.2011.02634.x.

PMID:
21401835
[PubMed - indexed for MEDLINE]
8.

A randomized, double-blind, active-controlled, double-dummy, parallel-group study to determine the safety and efficacy of oxycodone/naloxone prolonged-release tablets in patients with moderate/severe, chronic cancer pain.

Ahmedzai SH, Nauck F, Bar-Sela G, Bosse B, Leyendecker P, Hopp M.

Palliat Med. 2012 Jan;26(1):50-60. doi: 10.1177/0269216311418869. Epub 2011 Sep 21.

PMID:
21937568
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Prolonged-release oxycodone/naloxone in nonmalignant pain: single-center study in patients with constipation.

Gatti A, Casali M, Lazzari M, Tufaro G, Gafforio P, Silvestri C, Marcassa C, Sabato AF.

Adv Ther. 2013 Jan;30(1):41-59. doi: 10.1007/s12325-012-0074-0. Epub 2012 Dec 21.

PMID:
23269562
[PubMed - indexed for MEDLINE]
10.

Prolonged-release oxycodone/naloxone in postoperative pain management: from a randomized clinical trial to usual clinical practice.

Kuusniemi K, Zöllner J, Sjövall S, Huhtala J, Karjalainen P, Kokki M, Lemken J, Oppermann J, Kokki H.

J Int Med Res. 2012;40(5):1775-93.

PMID:
23206459
[PubMed - indexed for MEDLINE]
11.
12.

Combined oral prolonged-release oxycodone and naloxone in opioid-induced bowel dysfunction: review of efficacy and safety data in the treatment of patients experiencing chronic pain.

Clemens KE, Mikus G.

Expert Opin Pharmacother. 2010 Feb;11(2):297-310. doi: 10.1517/14656560903483222. Review.

PMID:
20030568
[PubMed - indexed for MEDLINE]
13.

Prolonged-release oxycodone/naloxone in the treatment of neuropathic pain - results from a large observational study.

Hermanns K, Junker U, Nolte T.

Expert Opin Pharmacother. 2012 Feb;13(3):299-311. doi: 10.1517/14656566.2012.648615. Epub 2012 Jan 6.

PMID:
22224497
[PubMed - indexed for MEDLINE]
14.

Opioids and the management of chronic severe pain in the elderly: consensus statement of an International Expert Panel with focus on the six clinically most often used World Health Organization Step III opioids (buprenorphine, fentanyl, hydromorphone, methadone, morphine, oxycodone).

Pergolizzi J, Böger RH, Budd K, Dahan A, Erdine S, Hans G, Kress HG, Langford R, Likar R, Raffa RB, Sacerdote P.

Pain Pract. 2008 Jul-Aug;8(4):287-313. doi: 10.1111/j.1533-2500.2008.00204.x. Epub 2008 May 23.

PMID:
18503626
[PubMed - indexed for MEDLINE]
15.

The role of opioid receptor antagonists in the treatment of opioid-induced constipation: a review.

Leppert W.

Adv Ther. 2010 Oct;27(10):714-30. doi: 10.1007/s12325-010-0063-0. Epub 2010 Aug 26. Review.

PMID:
20799006
[PubMed - indexed for MEDLINE]
16.

Meeting the challenges of opioid-induced constipation in chronic pain management - a novel approach.

Reimer K, Hopp M, Zenz M, Maier C, Holzer P, Mikus G, Bosse B, Smith K, Buschmann-Kramm C, Leyendecker P.

Pharmacology. 2009;83(1):10-7. doi: 10.1159/000165778. Epub 2008 Oct 28. Review.

PMID:
18957874
[PubMed - indexed for MEDLINE]
17.

Innovative pain therapy with a fixed combination of prolonged-release oxycodone/naloxone: a large observational study under conditions of daily practice.

Schutter U, Grunert S, Meyer C, Schmidt T, Nolte T.

Curr Med Res Opin. 2010 Jun;26(6):1377-87. doi: 10.1185/03007991003787318.

PMID:
20380506
[PubMed - indexed for MEDLINE]
18.

A comparison of oxycodone prolonged-release vs. oxycodone + naloxone prolonged-release after laparoscopic hysterectomy.

Comelon M, Wisloeff-Aase K, Raeder J, Draegni T, Undersrud H, Qvigstad E, Bjerkelund CE, Lenz H.

Acta Anaesthesiol Scand. 2013 Apr;57(4):509-17. doi: 10.1111/aas.12051. Epub 2013 Jan 10.

PMID:
23301686
[PubMed - indexed for MEDLINE]
19.

Targinact--opioid pain relief without constipation?

[No authors listed]

Drug Ther Bull. 2010 Dec;48(12):138-41. doi: 10.1136/dtb.2010.12.0061.

PMID:
21123290
[PubMed - indexed for MEDLINE]
20.

[New study demonstrates dual effect of an oxycodone/naloxone combination. Strong pain palliation and preserving intestinal function].

[No authors listed]

MMW Fortschr Med. 2007 Nov 29;149(48):50. German. No abstract available.

PMID:
18161439
[PubMed - indexed for MEDLINE]

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