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Items: 1 to 20 of 109

1.

A role for Jag2 in promoting uveal melanoma dissemination and growth.

Asnaghi L, Handa JT, Merbs SL, Harbour JW, Eberhart CG.

Invest Ophthalmol Vis Sci. 2013 Jan 9;54(1):295-306. doi: 10.1167/iovs.12-10209.

2.

EMT-associated factors promote invasive properties of uveal melanoma cells.

Asnaghi L, Gezgin G, Tripathy A, Handa JT, Merbs SL, van der Velden PA, Jager MJ, Harbour JW, Eberhart CG.

Mol Vis. 2015 Aug 25;21:919-29. eCollection 2015.

3.

Notch signaling promotes growth and invasion in uveal melanoma.

Asnaghi L, Ebrahimi KB, Schreck KC, Bar EE, Coonfield ML, Bell WR, Handa J, Merbs SL, Harbour JW, Eberhart CG.

Clin Cancer Res. 2012 Feb 1;18(3):654-65. doi: 10.1158/1078-0432.CCR-11-1406. Epub 2012 Jan 6.

4.

Hypoxia promotes uveal melanoma invasion through enhanced Notch and MAPK activation.

Asnaghi L, Lin MH, Lim KS, Lim KJ, Tripathy A, Wendeborn M, Merbs SL, Handa JT, Sodhi A, Bar EE, Eberhart CG.

PLoS One. 2014 Aug 28;9(8):e105372. doi: 10.1371/journal.pone.0105372. eCollection 2014.

5.

Involvement of PI3K/Akt signaling pathway in hepatocyte growth factor-induced migration of uveal melanoma cells.

Ye M, Hu D, Tu L, Zhou X, Lu F, Wen B, Wu W, Lin Y, Zhou Z, Qu J.

Invest Ophthalmol Vis Sci. 2008 Feb;49(2):497-504. doi: 10.1167/iovs.07-0975.

PMID:
18234991
6.

Loss of CCM3 impairs DLL4-Notch signalling: implication in endothelial angiogenesis and in inherited cerebral cavernous malformations.

You C, Sandalcioglu IE, Dammann P, Felbor U, Sure U, Zhu Y.

J Cell Mol Med. 2013 Mar;17(3):407-18. doi: 10.1111/jcmm.12022. Epub 2013 Feb 7.

7.

Distinct biological roles for the notch ligands Jagged-1 and Jagged-2.

Choi K, Ahn YH, Gibbons DL, Tran HT, Creighton CJ, Girard L, Minna JD, Qin FX, Kurie JM.

J Biol Chem. 2009 Jun 26;284(26):17766-74. doi: 10.1074/jbc.M109.003111. Epub 2009 Apr 27.

8.

Neuralized1 causes apoptosis and downregulates Notch target genes in medulloblastoma.

Teider N, Scott DK, Neiss A, Weeraratne SD, Amani VM, Wang Y, Marquez VE, Cho YJ, Pomeroy SL.

Neuro Oncol. 2010 Dec;12(12):1244-56. doi: 10.1093/neuonc/noq091. Epub 2010 Sep 16.

9.

Notch-Hes1 pathway contributes to the cochlear prosensory formation potentially through the transcriptional down-regulation of p27Kip1.

Murata J, Ohtsuka T, Tokunaga A, Nishiike S, Inohara H, Okano H, Kageyama R.

J Neurosci Res. 2009 Dec;87(16):3521-34. doi: 10.1002/jnr.22169.

PMID:
19598246
10.

MicroRNA-124a is epigenetically regulated and acts as a tumor suppressor by controlling multiple targets in uveal melanoma.

Chen X, He D, Dong XD, Dong F, Wang J, Wang L, Tang J, Hu DN, Yan D, Tu L.

Invest Ophthalmol Vis Sci. 2013 Mar 1;54(3):2248-56. doi: 10.1167/iovs.12-10977.

PMID:
23404119
11.

JAG2 induction in hypoxic tumor cells alters Notch signaling and enhances endothelial cell tube formation.

Pietras A, von Stedingk K, Lindgren D, Påhlman S, Axelson H.

Mol Cancer Res. 2011 May;9(5):626-36. doi: 10.1158/1541-7786.MCR-10-0508. Epub 2011 Mar 14.

12.
13.

Critical role of the NOTCH ligand JAG2 in self-renewal of myeloma cells.

Chiron D, Maïga S, Descamps G, Moreau P, Le Gouill S, Marionneau S, Ouiller T, Moreaux J, Klein B, Bataille R, Amiot M, Pellat-Deceunynck C.

Blood Cells Mol Dis. 2012 Apr 15;48(4):247-53. doi: 10.1016/j.bcmd.2012.01.006. Epub 2012 Feb 15.

PMID:
22341562
14.

How the NOTCH pathway contributes to the ability of osteosarcoma cells to metastasize.

Hughes DP.

Cancer Treat Res. 2009;152:479-96. doi: 10.1007/978-1-4419-0284-9_28. Review.

PMID:
20213410
15.

Mutant GNAQ promotes cell viability and migration of uveal melanoma cells through the activation of Notch signaling.

Liu H, Lei C, Long K, Yang X, Zhu Z, Zhang L, Liu J.

Oncol Rep. 2015 Jul;34(1):295-301. doi: 10.3892/or.2015.3949. Epub 2015 May 5.

PMID:
25955651
16.

The insulin-like growth factor-I receptor inhibitor picropodophyllin causes tumor regression and attenuates mechanisms involved in invasion of uveal melanoma cells.

Girnita A, All-Ericsson C, Economou MA, Aström K, Axelson M, Seregard S, Larsson O, Girnita L.

Clin Cancer Res. 2006 Feb 15;12(4):1383-91.

17.

Mda-9/syntenin is expressed in uveal melanoma and correlates with metastatic progression.

Gangemi R, Mirisola V, Barisione G, Fabbi M, Brizzolara A, Lanza F, Mosci C, Salvi S, Gualco M, Truini M, Angelini G, Boccardo S, Cilli M, Airoldi I, Queirolo P, Jager MJ, Daga A, Pfeffer U, Ferrini S.

PLoS One. 2012;7(1):e29989. doi: 10.1371/journal.pone.0029989. Epub 2012 Jan 13.

18.

MicroRNA-34a inhibits uveal melanoma cell proliferation and migration through downregulation of c-Met.

Yan D, Zhou X, Chen X, Hu DN, Dong XD, Wang J, Lu F, Tu L, Qu J.

Invest Ophthalmol Vis Sci. 2009 Apr;50(4):1559-65. doi: 10.1167/iovs.08-2681. Epub 2008 Nov 21.

PMID:
19029026
19.

17-AAG and 17-DMAG-induced inhibition of cell proliferation through B-Raf downregulation in WT B-Raf-expressing uveal melanoma cell lines.

Babchia N, Calipel A, Mouriaux F, Faussat AM, Mascarelli F.

Invest Ophthalmol Vis Sci. 2008 Jun;49(6):2348-56. doi: 10.1167/iovs.07-1305. Epub 2008 Feb 15.

PMID:
18281615
20.

Critical role of notch signaling in osteosarcoma invasion and metastasis.

Zhang P, Yang Y, Zweidler-McKay PA, Hughes DP.

Clin Cancer Res. 2008 May 15;14(10):2962-9. doi: 10.1158/1078-0432.CCR-07-1992. Retraction in: Zhang P, Yang Y, Zweidler-McKay P, Hughes DP. Clin Cancer Res. 2013 Sep 15;19(18):5256-7.

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