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Items: 1 to 20 of 110

1.

Hypoxia modulates A431 cellular pathways association to tumor radioresistance and enhanced migration revealed by comprehensive proteomic and functional studies.

Ren Y, Hao P, Dutta B, Cheow ES, Sim KH, Gan CS, Lim SK, Sze SK.

Mol Cell Proteomics. 2013 Feb;12(2):485-98. doi: 10.1074/mcp.M112.018325. Epub 2012 Nov 30.

2.

STAT1-dependent expression of energy metabolic pathways links tumour growth and radioresistance to the Warburg effect.

Pitroda SP, Wakim BT, Sood RF, Beveridge MG, Beckett MA, MacDermed DM, Weichselbaum RR, Khodarev NN.

BMC Med. 2009 Nov 5;7:68. doi: 10.1186/1741-7015-7-68.

3.

Induction of MET by ionizing radiation and its role in radioresistance and invasive growth of cancer.

De Bacco F, Luraghi P, Medico E, Reato G, Girolami F, Perera T, Gabriele P, Comoglio PM, Boccaccio C.

J Natl Cancer Inst. 2011 Apr 20;103(8):645-61. doi: 10.1093/jnci/djr093. Epub 2011 Apr 4.

4.

Adenovirus-mediated expression of a dominant negative Ku70 fragment radiosensitizes human tumor cells under aerobic and hypoxic conditions.

He F, Li L, Kim D, Wen B, Deng X, Gutin PH, Ling CC, Li GC.

Cancer Res. 2007 Jan 15;67(2):634-42.

5.

Clinicopathological significance of KU70/KU80, a key DNA damage repair protein in breast cancer.

Alshareeda AT, Negm OH, Albarakati N, Green AR, Nolan C, Sultana R, Madhusudan S, Benhasouna A, Tighe P, Ellis IO, Rakha EA.

Breast Cancer Res Treat. 2013 Jun;139(2):301-10. doi: 10.1007/s10549-013-2542-x. Epub 2013 Apr 28.

PMID:
23624778
6.

Adenovirus-mediated heat-activated antisense Ku70 expression radiosensitizes tumor cells in vitro and in vivo.

Li GC, He F, Shao X, Urano M, Shen L, Kim D, Borrelli M, Leibel SA, Gutin PH, Ling CC.

Cancer Res. 2003 Jun 15;63(12):3268-74.

7.

Hypoxia-induced changes to integrin α 3 glycosylation facilitate invasion in epidermoid carcinoma cell line A431.

Ren Y, Hao P, Law SK, Sze SK.

Mol Cell Proteomics. 2014 Nov;13(11):3126-37. doi: 10.1074/mcp.M114.038505. Epub 2014 Jul 30.

8.

KNK437, abrogates hypoxia-induced radioresistance by dual targeting of the AKT and HIF-1α survival pathways.

Oommen D, Prise KM.

Biochem Biophys Res Commun. 2012 May 11;421(3):538-43. doi: 10.1016/j.bbrc.2012.04.040. Epub 2012 Apr 13.

PMID:
22521642
9.
10.

DNA-dependent protein kinase is involved in heat shock protein-mediated accumulation of hypoxia-inducible factor-1alpha in hypoxic preconditioned HepG2 cells.

Kang MJ, Jung SM, Kim MJ, Bae JH, Kim HB, Kim JY, Park SJ, Song HS, Kim DW, Kang CD, Kim SH.

FEBS J. 2008 Dec;275(23):5969-81. doi: 10.1111/j.1742-4658.2008.06725.x.

11.

Proteomic analysis of gene expression following hypoxia and reoxygenation reveals proteins involved in the recovery from endoplasmic reticulum and oxidative stress.

Magagnin MG, Sergeant K, van den Beucken T, Rouschop KM, Jutten B, Seigneuric R, Lambin P, Devreese B, Koritzinsky M, Wouters BG.

Radiother Oncol. 2007 Jun;83(3):340-5. Epub 2007 May 24.

PMID:
17531340
12.

Regulation of DNA repair mechanism in human glioma xenograft cells both in vitro and in vivo in nude mice.

Ponnala S, Veeravalli KK, Chetty C, Dinh DH, Rao JS.

PLoS One. 2011;6(10):e26191. doi: 10.1371/journal.pone.0026191. Epub 2011 Oct 14.

13.

Response to multiple radiation doses of human colorectal carcinoma cells infected with recombinant adenovirus containing dominant-negative Ku70 fragment.

Urano M, He F, Minami A, Ling CC, Li GC.

Int J Radiat Oncol Biol Phys. 2010 Jul 1;77(3):877-85. doi: 10.1016/j.ijrobp.2009.12.062.

14.
15.

DNA ends alter the molecular composition and localization of Ku multicomponent complexes.

Adelmant G, Calkins AS, Garg BK, Card JD, Askenazi M, Miron A, Sobhian B, Zhang Y, Nakatani Y, Silver PA, Iglehart JD, Marto JA, Lazaro JB.

Mol Cell Proteomics. 2012 Aug;11(8):411-21. doi: 10.1074/mcp.M111.013581. Epub 2012 Apr 24.

16.

MiR-210 promotes a hypoxic phenotype and increases radioresistance in human lung cancer cell lines.

Grosso S, Doyen J, Parks SK, Bertero T, Paye A, Cardinaud B, Gounon P, Lacas-Gervais S, Noël A, Pouysségur J, Barbry P, Mazure NM, Mari B.

Cell Death Dis. 2013 Mar 14;4:e544. doi: 10.1038/cddis.2013.71.

17.

The radiosensitizing effect of Ku70/80 knockdown in MCF10A cells irradiated with X-rays and p(66)+Be(40) neutrons.

Vandersickel V, Mancini M, Slabbert J, Marras E, Thierens H, Perletti G, Vral A.

Radiat Oncol. 2010 Apr 27;5:30. doi: 10.1186/1748-717X-5-30.

18.

Hypoxia inducible factor 1α-mediated LOX expression correlates with migration and invasion in epithelial ovarian cancer.

Ji F, Wang Y, Qiu L, Li S, Zhu J, Liang Z, Wan Y, Di W.

Int J Oncol. 2013 May;42(5):1578-88. doi: 10.3892/ijo.2013.1878. Epub 2013 Mar 29.

19.

Establishment of ku70-deficient lung epithelial cell lines and their hypersensitivity to low-dose x-irradiation.

Koike M, Yutoku Y, Koike A.

J Vet Med Sci. 2011 May;73(5):549-54. Epub 2010 Dec 13.

20.

Hypoxia activated EGFR signaling induces epithelial to mesenchymal transition (EMT).

Misra A, Pandey C, Sze SK, Thanabalu T.

PLoS One. 2012;7(11):e49766. doi: 10.1371/journal.pone.0049766. Epub 2012 Nov 21.

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