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Items: 1 to 20 of 107

1.

Tanshinones: sources, pharmacokinetics and anti-cancer activities.

Zhang Y, Jiang P, Ye M, Kim SH, Jiang C, Lü J.

Int J Mol Sci. 2012 Oct 22;13(10):13621-66. doi: 10.3390/ijms131013621. Review.

2.

Tanshinones from Chinese medicinal herb Danshen (Salvia miltiorrhiza Bunge) suppress prostate cancer growth and androgen receptor signaling.

Zhang Y, Won SH, Jiang C, Lee HJ, Jeong SJ, Lee EO, Zhang J, Ye M, Kim SH, Lü J.

Pharm Res. 2012 Jun;29(6):1595-608. doi: 10.1007/s11095-012-0670-3. Epub 2012 Jan 27.

PMID:
22281759
3.

Modulation of esterified drug metabolism by tanshinones from Salvia miltiorrhiza ("Danshen").

Hatfield MJ, Tsurkan LG, Hyatt JL, Edwards CC, Lemoff A, Jeffries C, Yan B, Potter PM.

J Nat Prod. 2013 Jan 25;76(1):36-44. doi: 10.1021/np300628a. Epub 2013 Jan 3.

4.

Bioactive tanshinones in Salvia miltiorrhiza inhibit the growth of prostate cancer cells in vitro and in mice.

Gong Y, Li Y, Lu Y, Li L, Abdolmaleky H, Blackburn GL, Zhou JR.

Int J Cancer. 2011 Sep 1;129(5):1042-52. doi: 10.1002/ijc.25678. Epub 2010 Nov 3.

5.

Evaluation and SAR analysis of the cytotoxicity of tanshinones in colon cancer cells.

Wang L, Liu A, Zhang FL, Yeung JH, Li XQ, Cho CH.

Chin J Nat Med. 2014 Mar;12(3):167-71. doi: 10.1016/S1875-5364(14)60028-5.

PMID:
24702801
6.

Cytotoxicity of major tanshinones isolated from Danshen (Salvia miltiorrhiza) on HepG2 cells in relation to glutathione perturbation.

Lee WY, Chiu LC, Yeung JH.

Food Chem Toxicol. 2008 Jan;46(1):328-38. Epub 2007 Aug 21.

PMID:
17892911
7.

New developments in the chemistry and biology of the bioactive constituents of Tanshen.

Wang X, Morris-Natschke SL, Lee KH.

Med Res Rev. 2007 Jan;27(1):133-48. Review.

PMID:
16888751
8.

The anticancer properties of Salvia miltiorrhiza Bunge (Danshen): a systematic review.

Chen X, Guo J, Bao J, Lu J, Wang Y.

Med Res Rev. 2014 Jul;34(4):768-94. doi: 10.1002/med.21304. Epub 2013 Oct 7. Review.

PMID:
24123144
9.

Effects of tanshinones from Salvia miltiorrhiza on CYP2C19 activity in human liver microsomes: enzyme kinetic and molecular docking studies.

Hu T, Zhou X, Wang L, Or PM, Yeung JH, Kwan YW, Cho CH.

Chem Biol Interact. 2015 Mar 25;230:1-8. doi: 10.1016/j.cbi.2015.02.006. Epub 2015 Feb 14.

PMID:
25686904
10.

Reversal of P-glycoprotein (P-gp) mediated multidrug resistance in colon cancer cells by cryptotanshinone and dihydrotanshinone of Salvia miltiorrhiza.

Hu T, To KK, Wang L, Zhang L, Lu L, Shen J, Chan RL, Li M, Yeung JH, Cho CH.

Phytomedicine. 2014 Sep 25;21(11):1264-72. doi: 10.1016/j.phymed.2014.06.013. Epub 2014 Jul 25.

PMID:
25172788
11.

Biosynthesis, total syntheses, and antitumor activity of tanshinones and their analogs as potential therapeutic agents.

Dong Y, Morris-Natschke SL, Lee KH.

Nat Prod Rep. 2011 Mar;28(3):529-42. doi: 10.1039/c0np00035c. Epub 2011 Jan 12. Review.

PMID:
21225077
12.

New abietane norditerpenoid from Salvia miltiorrhiza with cytotoxic activities.

Yao F, Zhang DW, Qu GW, Li GS, Dai SJ.

J Asian Nat Prod Res. 2012;14(9):913-7. doi: 10.1080/10286020.2012.699962. Epub 2012 Aug 28.

PMID:
22924543
13.

Abietane diterpenes from Salvia miltiorrhiza inhibit the activation of hypoxia-inducible factor-1.

Dat NT, Jin X, Lee JH, Lee D, Hong YS, Lee K, Kim YH, Lee JJ.

J Nat Prod. 2007 Jul;70(7):1093-7. Epub 2007 Jun 21.

PMID:
17583950
14.

In Salvia miltiorrhiza, phenolic acids possess protective properties against amyloid β-induced cytotoxicity, and tanshinones act as acetylcholinesterase inhibitors.

Zhou Y, Li W, Xu L, Chen L.

Environ Toxicol Pharmacol. 2011 May;31(3):443-52. doi: 10.1016/j.etap.2011.02.006. Epub 2011 Feb 26.

PMID:
21787715
15.

[Growth inhibition of tanshinones on SPC-A-1 cell line and their structure-activity relationship].

Shi H, Zhang Q, Li H, Chu T, Jin H, Mao S.

Zhongguo Fei Ai Za Zhi. 2011 Jan;14(1):7-12. doi: 10.3779/j.issn.1009-3419.2011.01.02. Chinese.

16.

Molecular evidence of cryptotanshinone for treatment and prevention of human cancer.

Chen W, Lu Y, Chen G, Huang S.

Anticancer Agents Med Chem. 2013 Sep;13(7):979-87. Review.

17.

CYP76AH1 catalyzes turnover of miltiradiene in tanshinones biosynthesis and enables heterologous production of ferruginol in yeasts.

Guo J, Zhou YJ, Hillwig ML, Shen Y, Yang L, Wang Y, Zhang X, Liu W, Peters RJ, Chen X, Zhao ZK, Huang L.

Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):12108-13. doi: 10.1073/pnas.1218061110. Epub 2013 Jun 28.

18.

In vivo angiogenesis screening and mechanism of action of novel tanshinone derivatives produced by one-pot combinatorial modification of natural tanshinone mixture from Salvia miltiorrhiza.

Zhang ZR, Li JH, Li S, Liu AL, Hoi PM, Tian HY, Ye WC, Lee SM, Jiang RW.

PLoS One. 2014 Jul 3;9(7):e100416. doi: 10.1371/journal.pone.0100416. eCollection 2014.

19.

Comprehensive multi-channel multi-dimensional counter-current chromatography for separation of tanshinones from Salvia miltiorrhiza Bunge.

Meng J, Yang Z, Liang J, Zhou H, Wu S.

J Chromatogr A. 2014 Jan 3;1323:73-81. doi: 10.1016/j.chroma.2013.10.095. Epub 2013 Nov 6.

PMID:
24296293
20.

Angiogenesis: from plants to blood vessels.

Fan TP, Yeh JC, Leung KW, Yue PY, Wong RN.

Trends Pharmacol Sci. 2006 Jun;27(6):297-309. Epub 2006 May 11. Review.

PMID:
16697473
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