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Results: 1 to 20 of 138

1.

Cardioprotective effect of salvianolic acid B against arsenic trioxide-induced injury in cardiac H9c2 cells via the PI3K/Akt signal pathway.

Wang M, Sun GB, Sun X, Wang HW, Meng XB, Qin M, Sun J, Luo Y, Sun XB.

Toxicol Lett. 2013 Feb 4;216(2-3):100-7. doi: 10.1016/j.toxlet.2012.11.023. Epub 2012 Nov 30.

PMID:
23201927
[PubMed - indexed for MEDLINE]
2.

E3 ubiquitin ligase Cbl-b potentiates the apoptotic action of arsenic trioxide by inhibiting the PI3K/Akt pathway.

Yingchun L, Xiujuan Q, Jinglei Q, Ye Z, Jing L, Yuee T, Xuejun H, Kezuo H, Yunpeng L.

Braz J Med Biol Res. 2011 Feb;44(2):105-11. Epub 2010 Dec 17.

PMID:
21180886
[PubMed - indexed for MEDLINE]
Free Article
3.

Salvianolic acid A demonstrates cardioprotective effects in rat hearts and cardiomyocytes after ischemia/reperfusion injury.

Pan H, Li D, Fang F, Chen D, Qi L, Zhang R, Xu T, Sun H.

J Cardiovasc Pharmacol. 2011 Nov;58(5):535-42. doi: 10.1097/FJC.0b013e31822de355.

PMID:
21795988
[PubMed - indexed for MEDLINE]
4.

Picroside II protects cardiomyocytes from hypoxia/reoxygenation-induced apoptosis by activating the PI3K/Akt and CREB pathways.

Meng FJ, Jiao SM, Yu B.

Int J Mol Med. 2012 Aug;30(2):263-70. doi: 10.3892/ijmm.2012.987. Epub 2012 May 9.

PMID:
22581361
[PubMed - indexed for MEDLINE]
5.

Salvianolic acid B inhibits hydrogen peroxide-induced endothelial cell apoptosis through regulating PI3K/Akt signaling.

Liu CL, Xie LX, Li M, Durairajan SS, Goto S, Huang JD.

PLoS One. 2007 Dec 19;2(12):e1321.

PMID:
18091994
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Cardioprotective effect of Danshensu against myocardial ischemia/reperfusion injury and inhibits apoptosis of H9c2 cardiomyocytes via Akt and ERK1/2 phosphorylation.

Yin Y, Guan Y, Duan J, Wei G, Zhu Y, Quan W, Guo C, Zhou D, Wang Y, Xi M, Wen A.

Eur J Pharmacol. 2013 Jan 15;699(1-3):219-26. doi: 10.1016/j.ejphar.2012.11.005. Epub 2012 Nov 29.

PMID:
23200898
[PubMed - indexed for MEDLINE]
7.

αB-crystallin regulates oxidative stress-induced apoptosis in cardiac H9c2 cells via the PI3K/AKT pathway.

Xu F, Yu H, Liu J, Cheng L.

Mol Biol Rep. 2013 Mar;40(3):2517-26. doi: 10.1007/s11033-012-2332-2. Epub 2012 Dec 1.

PMID:
23212619
[PubMed - indexed for MEDLINE]
8.

Metallothionein prevention of arsenic trioxide-induced cardiac cell death is associated with its inhibition of mitogen-activated protein kinases activation in vitro and in vivo.

Miao X, Tang Z, Wang Y, Su G, Sun W, Wei W, Li W, Miao L, Cai L, Tan Y, Liu Q.

Toxicol Lett. 2013 Jul 18;220(3):277-85. doi: 10.1016/j.toxlet.2013.04.025. Epub 2013 May 9.

PMID:
23664956
[PubMed - indexed for MEDLINE]
9.

Arsenic trioxide induces apoptosis and G2/M phase arrest by inducing Cbl to inhibit PI3K/Akt signaling and thereby regulate p53 activation.

Li Y, Qu X, Qu J, Zhang Y, Liu J, Teng Y, Hu X, Hou K, Liu Y.

Cancer Lett. 2009 Nov 1;284(2):208-15. doi: 10.1016/j.canlet.2009.04.035. Epub 2009 May 19.

PMID:
19457607
[PubMed - indexed for MEDLINE]
10.

Quercetin protects oligodendrocyte precursor cells from oxygen/glucose deprivation injury in vitro via the activation of the PI3K/Akt signaling pathway.

Wang XQ, Yao RQ, Liu X, Huang JJ, Qi DS, Yang LH.

Brain Res Bull. 2011 Oct 10;86(3-4):277-84. doi: 10.1016/j.brainresbull.2011.07.014. Epub 2011 Jul 23.

PMID:
21803128
[PubMed - indexed for MEDLINE]
11.

DIDS attenuates staurosporine-induced cardiomyocyte apoptosis by PI3K/Akt signaling pathway: activation of eNOS/NO and inhibition of Bax translocation.

Liu AH, Cao YN, Liu HT, Zhang WW, Liu Y, Shi TW, Jia GL, Wang XM.

Cell Physiol Biochem. 2008;22(1-4):177-86. doi: 10.1159/000149795. Epub 2008 Jul 25.

PMID:
18769044
[PubMed - indexed for MEDLINE]
12.

Resveratrol protects against arsenic trioxide-induced cardiotoxicity in vitro and in vivo.

Zhao XY, Li GY, Liu Y, Chai LM, Chen JX, Zhang Y, Du ZM, Lu YJ, Yang BF.

Br J Pharmacol. 2008 May;154(1):105-13. doi: 10.1038/bjp.2008.81. Epub 2008 Mar 10.

PMID:
18332854
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Asperosaponin VI protects cardiac myocytes from hypoxia-induced apoptosis via activation of the PI3K/Akt and CREB pathways.

Li C, Tian J, Li G, Jiang W, Xing Y, Hou J, Zhu H, Xu H, Zhang G, Liu Z, Ye Z.

Eur J Pharmacol. 2010 Dec 15;649(1-3):100-7. doi: 10.1016/j.ejphar.2010.08.060. Epub 2010 Sep 20.

PMID:
20863824
[PubMed - indexed for MEDLINE]
14.

Arsenic trioxide induces autophagy and apoptosis in human glioma cells in vitro and in vivo through downregulation of survivin.

Chiu HW, Ho YS, Wang YJ.

J Mol Med (Berl). 2011 Sep;89(9):927-41. doi: 10.1007/s00109-011-0763-1. Epub 2011 May 19.

PMID:
21594580
[PubMed - indexed for MEDLINE]
15.

Increased apoptotic efficacy of lonidamine plus arsenic trioxide combination in human leukemia cells. Reactive oxygen species generation and defensive protein kinase (MEK/ERK, Akt/mTOR) modulation.

Calviño E, Estañ MC, Simón GP, Sancho P, Boyano-Adánez Mdel C, de Blas E, Bréard J, Aller P.

Biochem Pharmacol. 2011 Dec 1;82(11):1619-29. doi: 10.1016/j.bcp.2011.08.017. Epub 2011 Aug 27.

PMID:
21889928
[PubMed - indexed for MEDLINE]
16.

Activation of Akt/GSK-3beta signaling pathway is involved in intermedin(1-53) protection against myocardial apoptosis induced by ischemia/reperfusion.

Song JQ, Teng X, Cai Y, Tang CS, Qi YF.

Apoptosis. 2009 Sep;14(9):1061-9. doi: 10.1007/s10495-009-0382-2.

PMID:
19634012
[PubMed - indexed for MEDLINE]
17.

Direct stimulation of adult neural stem/progenitor cells in vitro and neurogenesis in vivo by salvianolic acid B.

Zhuang P, Zhang Y, Cui G, Bian Y, Zhang M, Zhang J, Liu Y, Yang X, Isaiah AO, Lin Y, Jiang Y.

PLoS One. 2012;7(4):e35636. doi: 10.1371/journal.pone.0035636. Epub 2012 Apr 24.

PMID:
22545124
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

5-AIQ inhibits H2O2-induced apoptosis through reactive oxygen species scavenging and Akt/GSK-3β signaling pathway in H9c2 cardiomyocytes.

Park ES, Kang JC, Kang DH, Jang YC, Yi KY, Chung HJ, Park JS, Kim B, Feng ZP, Shin HS.

Toxicol Appl Pharmacol. 2013 Apr 1;268(1):90-8. doi: 10.1016/j.taap.2013.01.004. Epub 2013 Jan 23.

PMID:
23352507
[PubMed - indexed for MEDLINE]
19.

Anti-apoptotic effect of heat shock protein 90 on hypoxia-mediated cardiomyocyte damage is mediated via the phosphatidylinositol 3-kinase/AKT pathway.

Wang W, Peng Y, Wang Y, Zhao X, Yuan Z.

Clin Exp Pharmacol Physiol. 2009 Sep;36(9):899-903. doi: 10.1111/j.1440-1681.2009.05167.x. Epub 2009 Mar 2.

PMID:
19298537
[PubMed - indexed for MEDLINE]
20.

Salidroside protects PC12 cells from MPP⁺-induced apoptosis via activation of the PI3K/Akt pathway.

Zhang L, Ding W, Sun H, Zhou Q, Huang J, Li X, Xie Y, Chen J.

Food Chem Toxicol. 2012 Aug;50(8):2591-7. doi: 10.1016/j.fct.2012.05.045. Epub 2012 Jun 1.

PMID:
22664423
[PubMed - indexed for MEDLINE]

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