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Results: 1 to 20 of 98

1.

Gene expression profiling of rotenone-mediated cortical neuronal death: evidence for inhibition of ubiquitin-proteasome system and autophagy-lysosomal pathway, and dysfunction of mitochondrial and calcium signaling.

Yap YW, Chen MJ, Peng ZF, Manikandan J, Ng JM, Llanos RM, La Fontaine S, Beart PM, Cheung NS.

Neurochem Int. 2013 Apr;62(5):653-63. doi: 10.1016/j.neuint.2012.11.011. Epub 2012 Nov 24.

PMID:
23186747
[PubMed - indexed for MEDLINE]
2.

Mitochondrial dysfunction precedes other sub-cellular abnormalities in an in vitro model linked with cell death in Parkinson's disease.

Yong-Kee CJ, Sidorova E, Hanif A, Perera G, Nash JE.

Neurotox Res. 2012 Feb;21(2):185-94. doi: 10.1007/s12640-011-9259-6. Epub 2011 Jul 20.

PMID:
21773851
[PubMed - indexed for MEDLINE]
3.

Gene profiling reveals hydrogen sulphide recruits death signaling via the N-methyl-D-aspartate receptor identifying commonalities with excitotoxicity.

Chen MJ, Peng ZF, Manikandan J, Melendez AJ, Tan GS, Chung CM, Li QT, Tan TM, Deng LW, Whiteman M, Beart PM, Moore PK, Cheung NS.

J Cell Physiol. 2011 May;226(5):1308-22. doi: 10.1002/jcp.22459.

PMID:
20945398
[PubMed - indexed for MEDLINE]
4.

Loss of caspase-2-dependent apoptosis induces autophagy after mitochondrial oxidative stress in primary cultures of young adult cortical neurons.

Tiwari M, Lopez-Cruzan M, Morgan WW, Herman B.

J Biol Chem. 2011 Mar 11;286(10):8493-506. doi: 10.1074/jbc.M110.163824. Epub 2011 Jan 7.

PMID:
21216964
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Rotenone inhibits autophagic flux prior to inducing cell death.

Mader BJ, Pivtoraiko VN, Flippo HM, Klocke BJ, Roth KA, Mangieri LR, Shacka JJ.

ACS Chem Neurosci. 2012 Dec 19;3(12):1063-72. doi: 10.1021/cn300145z. Epub 2012 Sep 13.

PMID:
23259041
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Intersecting pathways to neurodegeneration in Parkinson's disease: effects of the pesticide rotenone on DJ-1, alpha-synuclein, and the ubiquitin-proteasome system.

Betarbet R, Canet-Aviles RM, Sherer TB, Mastroberardino PG, McLendon C, Kim JH, Lund S, Na HM, Taylor G, Bence NF, Kopito R, Seo BB, Yagi T, Yagi A, Klinefelter G, Cookson MR, Greenamyre JT.

Neurobiol Dis. 2006 May;22(2):404-20. Epub 2006 Jan 24.

PMID:
16439141
[PubMed - indexed for MEDLINE]
7.

An in vitro model of Parkinson's disease: linking mitochondrial impairment to altered alpha-synuclein metabolism and oxidative damage.

Sherer TB, Betarbet R, Stout AK, Lund S, Baptista M, Panov AV, Cookson MR, Greenamyre JT.

J Neurosci. 2002 Aug 15;22(16):7006-15.

PMID:
12177198
[PubMed - indexed for MEDLINE]
Free Article
8.

Evidence for synergism between cell death mechanisms in a cellular model of neurodegeneration in Parkinson's disease.

Yong-Kee CJ, Warre R, Monnier PP, Lozano AM, Nash JE.

Neurotox Res. 2012 Nov;22(4):355-64. Epub 2012 Apr 20.

PMID:
22528248
[PubMed - indexed for MEDLINE]
9.

An inhibitor of mitochondrial complex I, rotenone, inactivates proteasome by oxidative modification and induces aggregation of oxidized proteins in SH-SY5Y cells.

Shamoto-Nagai M, Maruyama W, Kato Y, Isobe K, Tanaka M, Naoi M, Osawa T.

J Neurosci Res. 2003 Nov 15;74(4):589-97.

PMID:
14598303
[PubMed - indexed for MEDLINE]
10.

Involvement of macroautophagy in the dissolution of neuronal inclusions.

Rideout HJ, Lang-Rollin I, Stefanis L.

Int J Biochem Cell Biol. 2004 Dec;36(12):2551-62.

PMID:
15325592
[PubMed - indexed for MEDLINE]
11.

Microarray analysis of ethanol-treated cortical neurons reveals disruption of genes related to the ubiquitin-proteasome pathway and protein synthesis.

Gutala R, Wang J, Kadapakkam S, Hwang Y, Ticku M, Li MD.

Alcohol Clin Exp Res. 2004 Dec;28(12):1779-88.

PMID:
15608593
[PubMed - indexed for MEDLINE]
12.

Rapamycin protects against rotenone-induced apoptosis through autophagy induction.

Pan T, Rawal P, Wu Y, Xie W, Jankovic J, Le W.

Neuroscience. 2009 Dec 1;164(2):541-51. doi: 10.1016/j.neuroscience.2009.08.014. Epub 2009 Aug 12.

PMID:
19682553
[PubMed - indexed for MEDLINE]
13.

Does impairment of the ubiquitin-proteasome system or the autophagy-lysosome pathway predispose individuals to neurodegenerative disorders such as Parkinson's disease?

Matsuda N, Tanaka K.

J Alzheimers Dis. 2010;19(1):1-9. doi: 10.3233/JAD-2010-1231. Review.

PMID:
20061621
[PubMed - indexed for MEDLINE]
14.

Low dose rotenone treatment causes selective transcriptional activation of cell death related pathways in dopaminergic neurons in vivo.

Meurers BH, Zhu C, Fernagut PO, Richter F, Hsia YC, Fleming SM, Oh M, Elashoff D, Dicarlo CD, Seaman RL, Chesselet MF.

Neurobiol Dis. 2009 Feb;33(2):182-92. doi: 10.1016/j.nbd.2008.10.001. Epub 2008 Oct 26.

PMID:
19013527
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Transcriptome analysis reveals link between proteasomal and mitochondrial pathways in Parkinson's disease.

Duke DC, Moran LB, Kalaitzakis ME, Deprez M, Dexter DT, Pearce RK, Graeber MB.

Neurogenetics. 2006 Jul;7(3):139-48. Epub 2006 May 13.

PMID:
16699787
[PubMed - indexed for MEDLINE]
16.

Mechanisms of rotenone-induced proteasome inhibition.

Chou AP, Li S, Fitzmaurice AG, Bronstein JM.

Neurotoxicology. 2010 Aug;31(4):367-72. doi: 10.1016/j.neuro.2010.04.006. Epub 2010 Apr 22.

PMID:
20417232
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

The mitochondrial complex I inhibitor rotenone triggers a cerebral tauopathy.

Höglinger GU, Lannuzel A, Khondiker ME, Michel PP, Duyckaerts C, Féger J, Champy P, Prigent A, Medja F, Lombes A, Oertel WH, Ruberg M, Hirsch EC.

J Neurochem. 2005 Nov;95(4):930-9. Epub 2005 Aug 10.

PMID:
16219024
[PubMed - indexed for MEDLINE]
18.

Mitochondrial electron-transport-chain inhibitors of complexes I and II induce autophagic cell death mediated by reactive oxygen species.

Chen Y, McMillan-Ward E, Kong J, Israels SJ, Gibson SB.

J Cell Sci. 2007 Dec 1;120(Pt 23):4155-66.

PMID:
18032788
[PubMed - indexed for MEDLINE]
Free Article
19.

Neuroprotection of kaempferol by autophagy in models of rotenone-mediated acute toxicity: possible implications for Parkinson's disease.

Filomeni G, Graziani I, De Zio D, Dini L, Centonze D, Rotilio G, Ciriolo MR.

Neurobiol Aging. 2012 Apr;33(4):767-85. doi: 10.1016/j.neurobiolaging.2010.05.021. Epub 2010 Jul 1.

PMID:
20594614
[PubMed - indexed for MEDLINE]
20.

The role of ubiquitin linkages on alpha-synuclein induced-toxicity in a Drosophila model of Parkinson's disease.

Lee FK, Wong AK, Lee YW, Wan OW, Chan HY, Chung KK.

J Neurochem. 2009 Jul;110(1):208-19. doi: 10.1111/j.1471-4159.2009.06124.x. Epub 2009 Apr 27.

PMID:
19457126
[PubMed - indexed for MEDLINE]

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