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Results: 1 to 20 of 156

1.

The gamma chain subunit of Fc receptors is required for alpha-synuclein-induced pro-inflammatory signaling in microglia.

Cao S, Standaert DG, Harms AS.

J Neuroinflammation. 2012 Nov 27;9:259. doi: 10.1186/1742-2094-9-259.

PMID:
23186369
[PubMed - indexed for MEDLINE]
Free PMC Article
2.
3.

Aggregated alpha-synuclein activates microglia: a process leading to disease progression in Parkinson's disease.

Zhang W, Wang T, Pei Z, Miller DS, Wu X, Block ML, Wilson B, Zhang W, Zhou Y, Hong JS, Zhang J.

FASEB J. 2005 Apr;19(6):533-42.

PMID:
15791003
[PubMed - indexed for MEDLINE]
Free Article
4.

Nitrated alpha-synuclein-activated microglial profiling for Parkinson's disease.

Reynolds AD, Glanzer JG, Kadiu I, Ricardo-Dukelow M, Chaudhuri A, Ciborowski P, Cerny R, Gelman B, Thomas MP, Mosley RL, Gendelman HE.

J Neurochem. 2008 Mar;104(6):1504-25. Epub 2007 Nov 22.

PMID:
18036154
[PubMed - indexed for MEDLINE]
5.

Nitrated alpha-synuclein and microglial neuroregulatory activities.

Reynolds AD, Kadiu I, Garg SK, Glanzer JG, Nordgren T, Ciborowski P, Banerjee R, Gendelman HE.

J Neuroimmune Pharmacol. 2008 Jun;3(2):59-74. doi: 10.1007/s11481-008-9100-z. Epub 2008 Jan 17.

PMID:
18202920
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Neuroinflammation and α-synuclein dysfunction potentiate each other, driving chronic progression of neurodegeneration in a mouse model of Parkinson's disease.

Gao HM, Zhang F, Zhou H, Kam W, Wilson B, Hong JS.

Environ Health Perspect. 2011 Jun;119(6):807-14. doi: 10.1289/ehp.1003013. Epub 2011 Jan 18.

PMID:
21245015
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

In vivo modulation of polo-like kinases supports a key role for PLK2 in Ser129 α-synuclein phosphorylation in mouse brain.

Bergeron M, Motter R, Tanaka P, Fauss D, Babcock M, Chiou SS, Nelson S, San Pablo F, Anderson JP.

Neuroscience. 2014 Jan 3;256:72-82. doi: 10.1016/j.neuroscience.2013.09.061. Epub 2013 Oct 12.

PMID:
24128992
[PubMed - indexed for MEDLINE]
8.

Suppression of MAP kinases inhibits microglial activation and attenuates neuronal cell death induced by alpha-synuclein protofibrils.

Wilms H, Rosenstiel P, Romero-Ramos M, Arlt A, Schäfer H, Seegert D, Kahle PJ, Odoy S, Claasen JH, Holzknecht C, Brandenburg LO, Deuschl G, Schreiber S, Kirik D, Lucius R.

Int J Immunopathol Pharmacol. 2009 Oct-Dec;22(4):897-909.

PMID:
20074453
[PubMed - indexed for MEDLINE]
9.

Fcgamma receptor I- and III-mediated macrophage inflammatory protein 1alpha induction in primary human and murine microglia.

Song X, Shapiro S, Goldman DL, Casadevall A, Scharff M, Lee SC.

Infect Immun. 2002 Sep;70(9):5177-84.

PMID:
12183568
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

MHCII is required for α-synuclein-induced activation of microglia, CD4 T cell proliferation, and dopaminergic neurodegeneration.

Harms AS, Cao S, Rowse AL, Thome AD, Li X, Mangieri LR, Cron RQ, Shacka JJ, Raman C, Standaert DG.

J Neurosci. 2013 Jun 5;33(23):9592-600. doi: 10.1523/JNEUROSCI.5610-12.2013.

PMID:
23739956
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Neuron-derived IgG protects dopaminergic neurons from insult by 6-OHDA and activates microglia through the FcγR I and TLR4 pathways.

Zhang J, Niu N, Wang M, McNutt MA, Zhang D, Zhang B, Lu S, Liu Y, Liu Z.

Int J Biochem Cell Biol. 2013 Aug;45(8):1911-20. doi: 10.1016/j.biocel.2013.06.005. Epub 2013 Jun 17.

PMID:
23791745
[PubMed - indexed for MEDLINE]
12.

Mineralocorticoid and glucocorticoid receptors differentially regulate NF-kappaB activity and pro-inflammatory cytokine production in murine BV-2 microglial cells.

Chantong B, Kratschmar DV, Nashev LG, Balazs Z, Odermatt A.

J Neuroinflammation. 2012 Nov 28;9:260. doi: 10.1186/1742-2094-9-260.

PMID:
23190711
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Regionally-specific microglial activation in young mice over-expressing human wildtype alpha-synuclein.

Watson MB, Richter F, Lee SK, Gabby L, Wu J, Masliah E, Effros RB, Chesselet MF.

Exp Neurol. 2012 Oct;237(2):318-34. doi: 10.1016/j.expneurol.2012.06.025. Epub 2012 Jun 27.

PMID:
22750327
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Heme activates TLR4-mediated inflammatory injury via MyD88/TRIF signaling pathway in intracerebral hemorrhage.

Lin S, Yin Q, Zhong Q, Lv FL, Zhou Y, Li JQ, Wang JZ, Su BY, Yang QW.

J Neuroinflammation. 2012 Mar 6;9:46. doi: 10.1186/1742-2094-9-46.

PMID:
22394415
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Neuroinflammation and oxidation/nitration of alpha-synuclein linked to dopaminergic neurodegeneration.

Gao HM, Kotzbauer PT, Uryu K, Leight S, Trojanowski JQ, Lee VM.

J Neurosci. 2008 Jul 23;28(30):7687-98. doi: 10.1523/JNEUROSCI.0143-07.2008.

PMID:
18650345
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Mutant alpha-synuclein overexpression mediates early proinflammatory activity.

Su X, Federoff HJ, Maguire-Zeiss KA.

Neurotox Res. 2009 Oct;16(3):238-54. doi: 10.1007/s12640-009-9053-x. Epub 2009 Apr 28.

PMID:
19526281
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Role of Fcgamma receptors in nigral cell injury induced by Parkinson disease immunoglobulin injection into mouse substantia nigra.

He Y, Le WD, Appel SH.

Exp Neurol. 2002 Aug;176(2):322-7.

PMID:
12359173
[PubMed - indexed for MEDLINE]
18.

Nitrated alpha-synuclein immunity accelerates degeneration of nigral dopaminergic neurons.

Benner EJ, Banerjee R, Reynolds AD, Sherman S, Pisarev VM, Tsiperson V, Nemachek C, Ciborowski P, Przedborski S, Mosley RL, Gendelman HE.

PLoS One. 2008 Jan 2;3(1):e1376. doi: 10.1371/journal.pone.0001376.

PMID:
18167537
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Alpha-synuclein aggregation and cell death triggered by energy deprivation and dopamine overload are counteracted by D2/D3 receptor activation.

Bellucci A, Collo G, Sarnico I, Battistin L, Missale C, Spano P.

J Neurochem. 2008 Jul;106(2):560-77. doi: 10.1111/j.1471-4159.2008.05406.x. Epub 2008 Apr 10.

PMID:
18410503
[PubMed - indexed for MEDLINE]
20.

Alpha-synuclein induces migration of BV-2 microglial cells by up-regulation of CD44 and MT1-MMP.

Kim S, Cho SH, Kim KY, Shin KY, Kim HS, Park CH, Chang KA, Lee SH, Cho D, Suh YH.

J Neurochem. 2009 Jun;109(5):1483-96. doi: 10.1111/j.1471-4159.2009.06075.x. Epub 2009 Mar 30.

PMID:
19457162
[PubMed - indexed for MEDLINE]

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