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Down-regulation of the ALS3 gene as a consequent effect of RNA-mediated silencing of the EFG1 gene in Candida albicans.

Moazeni M, Khorramizadeh MR, Teimoori-Toolabi L, Noorbakhsh F, Fallahi AA, Rezaie S.

Iran Biomed J. 2012;16(4):172-8.


The effect of EFG1 gene silencing on down-regulation of SAP5 gene, by use of RNAi technology.

Moazeni M, Khoramizadeh MR, Teimoori-Toolabi L, Noorbakhsh F, Rezaie S.

Acta Med Iran. 2014;52(1):9-14.


RNA-mediated gene silencing in Candida albicans: inhibition of hyphae formation by use of RNAi technology.

Moazeni M, Khoramizadeh MR, Kordbacheh P, Sepehrizadeh Z, Zeraati H, Noorbakhsh F, Teimoori-Toolabi L, Rezaie S.

Mycopathologia. 2012 Sep;174(3):177-85. doi: 10.1007/s11046-012-9539-6. Epub 2012 Apr 7.


The Flo8 transcription factor is essential for hyphal development and virulence in Candida albicans.

Cao F, Lane S, Raniga PP, Lu Y, Zhou Z, Ramon K, Chen J, Liu H.

Mol Biol Cell. 2006 Jan;17(1):295-307. Epub 2005 Nov 2.


Developmental regulation of an adhesin gene during cellular morphogenesis in the fungal pathogen Candida albicans.

Argimón S, Wishart JA, Leng R, Macaskill S, Mavor A, Alexandris T, Nicholls S, Knight AW, Enjalbert B, Walmsley R, Odds FC, Gow NA, Brown AJ.

Eukaryot Cell. 2007 Apr;6(4):682-92. Epub 2007 Feb 2.


Candida albicans hyphal formation and the expression of the Efg1-regulated proteinases Sap4 to Sap6 are required for the invasion of parenchymal organs.

Felk A, Kretschmar M, Albrecht A, Schaller M, Beinhauer S, Nichterlein T, Sanglard D, Korting HC, Schäfer W, Hube B.

Infect Immun. 2002 Jul;70(7):3689-700.


Transcriptional regulators Cph1p and Efg1p mediate activation of the Candida albicans virulence gene SAP5 during infection.

Staib P, Kretschmar M, Nichterlein T, Hof H, Morschhäuser J.

Infect Immun. 2002 Feb;70(2):921-7.


Reduced expression of the hyphal-independent Candida albicans proteinase genes SAP1 and SAP3 in the efg1 mutant is associated with attenuated virulence during infection of oral epithelium.

Korting HC, Hube B, Oberbauer S, Januschke E, Hamm G, Albrecht A, Borelli C, Schaller M.

J Med Microbiol. 2003 Aug;52(Pt 8):623-32.


EFG1 is a major regulator of cell wall dynamics in Candida albicans as revealed by DNA microarrays.

Sohn K, Urban C, Brunner H, Rupp S.

Mol Microbiol. 2003 Jan;47(1):89-102.


Target specificity of the Candida albicans Efg1 regulator.

Lassak T, Schneider E, Bussmann M, Kurtz D, Manak JR, Srikantha T, Soll DR, Ernst JF.

Mol Microbiol. 2011 Nov;82(3):602-18. doi: 10.1111/j.1365-2958.2011.07837.x. Epub 2011 Oct 10.


Normal adaptation of Candida albicans to the murine gastrointestinal tract requires Efg1p-dependent regulation of metabolic and host defense genes.

Pierce JV, Dignard D, Whiteway M, Kumamoto CA.

Eukaryot Cell. 2013 Jan;12(1):37-49. doi: 10.1128/EC.00236-12. Epub 2012 Nov 2.


Efg1-mediated recruitment of NuA4 to promoters is required for hypha-specific Swi/Snf binding and activation in Candida albicans.

Lu Y, Su C, Mao X, Raniga PP, Liu H, Chen J.

Mol Biol Cell. 2008 Oct;19(10):4260-72. doi: 10.1091/mbc.E08-02-0173. Epub 2008 Aug 6.


Efg1 involved in drug resistance by regulating the expression of ERG3 in Candida albicans.

Lo HJ, Wang JS, Lin CY, Chen CG, Hsiao TY, Hsu CT, Su CL, Fann MJ, Ching YT, Yang YL.

Antimicrob Agents Chemother. 2005 Mar;49(3):1213-5.


Hypoxic adaptation by Efg1 regulates biofilm formation by Candida albicans.

Stichternoth C, Ernst JF.

Appl Environ Microbiol. 2009 Jun;75(11):3663-72. doi: 10.1128/AEM.00098-09. Epub 2009 Apr 3.


Adaptation of the Efg1p morphogenetic pathway in Candida albicans by negative autoregulation and PKA-dependent repression of the EFG1 gene.

Tebarth B, Doedt T, Krishnamurthy S, Weide M, Monterola F, Dominguez A, Ernst JF.

J Mol Biol. 2003 Jun 20;329(5):949-62.


DNA array studies demonstrate convergent regulation of virulence factors by Cph1, Cph2, and Efg1 in Candida albicans.

Lane S, Birse C, Zhou S, Matson R, Liu H.

J Biol Chem. 2001 Dec 28;276(52):48988-96. Epub 2001 Oct 10.


Hyphal chain formation in Candida albicans: Cdc28-Hgc1 phosphorylation of Efg1 represses cell separation genes.

Wang A, Raniga PP, Lane S, Lu Y, Liu H.

Mol Cell Biol. 2009 Aug;29(16):4406-16. doi: 10.1128/MCB.01502-08. Epub 2009 Jun 15.


Candida albicans Als1p: an adhesin that is a downstream effector of the EFG1 filamentation pathway.

Fu Y, Ibrahim AS, Sheppard DC, Chen YC, French SW, Cutler JE, Filler SG, Edwards JE Jr.

Mol Microbiol. 2002 Apr;44(1):61-72.


HWP1 functions in the morphological development of Candida albicans downstream of EFG1, TUP1, and RBF1.

Sharkey LL, McNemar MD, Saporito-Irwin SM, Sypherd PS, Fonzi WA.

J Bacteriol. 1999 Sep;181(17):5273-9.

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