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Results: 1 to 20 of 107

1.

The SOSS1 single-stranded DNA binding complex promotes DNA end resection in concert with Exo1.

Yang SH, Zhou R, Campbell J, Chen J, Ha T, Paull TT.

EMBO J. 2013 Jan 9;32(1):126-39. doi: 10.1038/emboj.2012.314. Epub 2012 Nov 23.

PMID:
23178594
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

BLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair.

Nimonkar AV, Genschel J, Kinoshita E, Polaczek P, Campbell JL, Wyman C, Modrich P, Kowalczykowski SC.

Genes Dev. 2011 Feb 15;25(4):350-62. doi: 10.1101/gad.2003811.

PMID:
21325134
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Release of Ku and MRN from DNA ends by Mre11 nuclease activity and Ctp1 is required for homologous recombination repair of double-strand breaks.

Langerak P, Mejia-Ramirez E, Limbo O, Russell P.

PLoS Genet. 2011 Sep;7(9):e1002271. doi: 10.1371/journal.pgen.1002271. Epub 2011 Sep 8.

PMID:
21931565
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks.

Bolderson E, Tomimatsu N, Richard DJ, Boucher D, Kumar R, Pandita TK, Burma S, Khanna KK.

Nucleic Acids Res. 2010 Apr;38(6):1821-31. doi: 10.1093/nar/gkp1164. Epub 2009 Dec 17.

PMID:
20019063
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Human Ku70/80 protein blocks exonuclease 1-mediated DNA resection in the presence of human Mre11 or Mre11/Rad50 protein complex.

Sun J, Lee KJ, Davis AJ, Chen DJ.

J Biol Chem. 2012 Feb 10;287(7):4936-45. doi: 10.1074/jbc.M111.306167. Epub 2011 Dec 15.

PMID:
22179609
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Relationship of DNA degradation by Saccharomyces cerevisiae exonuclease 1 and its stimulation by RPA and Mre11-Rad50-Xrs2 to DNA end resection.

Cannavo E, Cejka P, Kowalczykowski SC.

Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):E1661-8. doi: 10.1073/pnas.1305166110. Epub 2013 Apr 15.

PMID:
23589858
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

DNA double-strand break repair pathway choice is directed by distinct MRE11 nuclease activities.

Shibata A, Moiani D, Arvai AS, Perry J, Harding SM, Genois MM, Maity R, van Rossum-Fikkert S, Kertokalio A, Romoli F, Ismail A, Ismalaj E, Petricci E, Neale MJ, Bristow RG, Masson JY, Wyman C, Jeggo PA, Tainer JA.

Mol Cell. 2014 Jan 9;53(1):7-18. doi: 10.1016/j.molcel.2013.11.003. Epub 2013 Dec 5.

PMID:
24316220
[PubMed - indexed for MEDLINE]
8.

RPA coordinates DNA end resection and prevents formation of DNA hairpins.

Chen H, Lisby M, Symington LS.

Mol Cell. 2013 May 23;50(4):589-600. doi: 10.1016/j.molcel.2013.04.032.

PMID:
23706822
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

hSSB1 interacts directly with the MRN complex stimulating its recruitment to DNA double-strand breaks and its endo-nuclease activity.

Richard DJ, Cubeddu L, Urquhart AJ, Bain A, Bolderson E, Menon D, White MF, Khanna KK.

Nucleic Acids Res. 2011 May;39(9):3643-51. doi: 10.1093/nar/gkq1340. Epub 2011 Jan 11.

PMID:
21227926
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Exo1 plays a major role in DNA end resection in humans and influences double-strand break repair and damage signaling decisions.

Tomimatsu N, Mukherjee B, Deland K, Kurimasa A, Bolderson E, Khanna KK, Burma S.

DNA Repair (Amst). 2012 Apr 1;11(4):441-8. doi: 10.1016/j.dnarep.2012.01.006. Epub 2012 Feb 11.

PMID:
22326273
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

hSSB1 rapidly binds at the sites of DNA double-strand breaks and is required for the efficient recruitment of the MRN complex.

Richard DJ, Savage K, Bolderson E, Cubeddu L, So S, Ghita M, Chen DJ, White MF, Richard K, Prise KM, Schettino G, Khanna KK.

Nucleic Acids Res. 2011 Mar;39(5):1692-702. doi: 10.1093/nar/gkq1098. Epub 2010 Nov 3.

PMID:
21051358
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes.

Zou L, Elledge SJ.

Science. 2003 Jun 6;300(5625):1542-8.

PMID:
12791985
[PubMed - indexed for MEDLINE]
Free Article
13.

DNA annealing by RAD52 protein is stimulated by specific interaction with the complex of replication protein A and single-stranded DNA.

Sugiyama T, New JH, Kowalczykowski SC.

Proc Natl Acad Sci U S A. 1998 May 26;95(11):6049-54.

PMID:
9600915
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Dynamic regulatory interactions of rad51, rad52, and replication protein-a in recombination intermediates.

Sugiyama T, Kantake N.

J Mol Biol. 2009 Jul 3;390(1):45-55. doi: 10.1016/j.jmb.2009.05.009. Epub 2009 May 13.

PMID:
19445949
[PubMed - indexed for MEDLINE]
15.

Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair.

Nimonkar AV, Ozsoy AZ, Genschel J, Modrich P, Kowalczykowski SC.

Proc Natl Acad Sci U S A. 2008 Nov 4;105(44):16906-11. doi: 10.1073/pnas.0809380105. Epub 2008 Oct 29.

PMID:
18971343
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

SOSS complexes participate in the maintenance of genomic stability.

Huang J, Gong Z, Ghosal G, Chen J.

Mol Cell. 2009 Aug 14;35(3):384-93. doi: 10.1016/j.molcel.2009.06.011.

PMID:
19683501
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

MRE11-RAD50-NBS1 complex dictates DNA repair independent of H2AX.

Yuan J, Chen J.

J Biol Chem. 2010 Jan 8;285(2):1097-104. doi: 10.1074/jbc.M109.078436. Epub 2009 Nov 12.

PMID:
19910469
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Cdk1 uncouples CtIP-dependent resection and Rad51 filament formation during M-phase double-strand break repair.

Peterson SE, Li Y, Chait BT, Gottesman ME, Baer R, Gautier J.

J Cell Biol. 2011 Sep 5;194(5):705-20. doi: 10.1083/jcb.201103103.

PMID:
21893598
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

DNA end resection by Dna2-Sgs1-RPA and its stimulation by Top3-Rmi1 and Mre11-Rad50-Xrs2.

Cejka P, Cannavo E, Polaczek P, Masuda-Sasa T, Pokharel S, Campbell JL, Kowalczykowski SC.

Nature. 2010 Sep 2;467(7311):112-6. doi: 10.1038/nature09355.

PMID:
20811461
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

DNA end resection by CtIP and exonuclease 1 prevents genomic instability.

Eid W, Steger M, El-Shemerly M, Ferretti LP, Peña-Diaz J, König C, Valtorta E, Sartori AA, Ferrari S.

EMBO Rep. 2010 Dec;11(12):962-8. doi: 10.1038/embor.2010.157. Epub 2010 Nov 5.

PMID:
21052091
[PubMed - indexed for MEDLINE]
Free PMC Article

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