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Results: 1 to 20 of 100

1.

Nucleoside/nucleotide analogue polymerase inhibitors in development.

Pockros PJ.

Clin Liver Dis. 2013 Feb;17(1):105-10. doi: 10.1016/j.cld.2012.09.007. Review.

PMID:
23177286
[PubMed - indexed for MEDLINE]
2.

New NS5B polymerase inhibitors for hepatitis C.

Legrand-Abravanel F, Nicot F, Izopet J.

Expert Opin Investig Drugs. 2010 Aug;19(8):963-75. doi: 10.1517/13543784.2010.500285. Review.

PMID:
20629614
[PubMed - indexed for MEDLINE]
3.

The HCV NS5B nucleoside and non-nucleoside inhibitors.

Membreno FE, Lawitz EJ.

Clin Liver Dis. 2011 Aug;15(3):611-26. doi: 10.1016/j.cld.2011.05.003. Review.

PMID:
21867940
[PubMed - indexed for MEDLINE]
4.

Efficacy of nucleotide polymerase inhibitor sofosbuvir plus the NS5A inhibitor ledipasvir or the NS5B non-nucleoside inhibitor GS-9669 against HCV genotype 1 infection.

Gane EJ, Stedman CA, Hyland RH, Ding X, Svarovskaia E, Subramanian GM, Symonds WT, McHutchison JG, Pang PS.

Gastroenterology. 2014 Mar;146(3):736-743.e1. doi: 10.1053/j.gastro.2013.11.007. Epub 2013 Nov 18.

PMID:
24262278
[PubMed - indexed for MEDLINE]
5.

Non-nucleoside inhibitors of the HCV NS5B polymerase: progress in the discovery and development of novel agents for the treatment of HCV infections.

Beaulieu PL.

Curr Opin Investig Drugs. 2007 Aug;8(8):614-34. Review.

PMID:
17668364
[PubMed - indexed for MEDLINE]
6.

A novel promising therapeutic option against hepatitis C virus: an oral nucleotide NS5B polymerase inhibitor sofosbuvir.

Gentile I, Borgia F, Buonomo AR, Castaldo G, Borgia G.

Curr Med Chem. 2013;20(30):3733-42. Review.

PMID:
23848533
[PubMed - indexed for MEDLINE]
7.

Nucleoside, nucleotide, and non-nucleoside inhibitors of hepatitis C virus NS5B RNA-dependent RNA-polymerase.

Sofia MJ, Chang W, Furman PA, Mosley RT, Ross BS.

J Med Chem. 2012 Mar 22;55(6):2481-531. doi: 10.1021/jm201384j. Epub 2012 Jan 23. Review. No abstract available.

PMID:
22185586
[PubMed - indexed for MEDLINE]
8.

Sofosbuvir for the treatment of hepatitis C virus.

Asselah T.

Expert Opin Pharmacother. 2014 Jan;15(1):121-30. doi: 10.1517/14656566.2014.857656. Epub 2013 Nov 30. Review.

PMID:
24289735
[PubMed - indexed for MEDLINE]
9.

Current perspective of HCV NS5B inhibitors: a review.

Patil VM, Gupta SP, Samanta S, Masand N.

Curr Med Chem. 2011;18(36):5564-97. Review.

PMID:
22172066
[PubMed - indexed for MEDLINE]
10.

Progress in the development of anti-hepatitis C virus nucleoside and nucleotide prodrugs.

Madela K, McGuigan C.

Future Med Chem. 2012 Apr;4(5):625-50. doi: 10.4155/fmc.12.10. Review.

PMID:
22458682
[PubMed - indexed for MEDLINE]
11.
12.

All-oral therapy with nucleotide inhibitors sofosbuvir and GS-0938 for 14 days in treatment-naive genotype 1 hepatitis C (nuclear).

Lawitz EJ, Rodriguez-Torres M, Denning J, Mathias A, Mo H, Gao B, Cornpropst MT, Berrey MM, Symonds WT.

J Viral Hepat. 2013 Oct;20(10):699-707. doi: 10.1111/jvh.12091. Epub 2013 Mar 31.

PMID:
24010644
[PubMed - indexed for MEDLINE]
13.

Inhibition of native hepatitis C virus replicase by nucleotide and non-nucleoside inhibitors.

Ma H, Leveque V, De Witte A, Li W, Hendricks T, Clausen SM, Cammack N, Klumpp K.

Virology. 2005 Feb 5;332(1):8-15.

PMID:
15661135
[PubMed - indexed for MEDLINE]
Free Article
14.

Non-nucleoside inhibitors of the HCV polymerase.

Sarisky RT.

J Antimicrob Chemother. 2004 Jul;54(1):14-6. Epub 2004 Jun 9. Review.

PMID:
15190019
[PubMed - indexed for MEDLINE]
Free Article
15.

RNA dependent RNA polymerase of HCV: a potential target for the development of antiviral drugs.

Waheed Y, Bhatti A, Ashraf M.

Infect Genet Evol. 2013 Mar;14:247-57. doi: 10.1016/j.meegid.2012.12.004. Epub 2013 Jan 2.

PMID:
23291407
[PubMed - indexed for MEDLINE]
16.

Hepatitis C therapy with HCV NS5B polymerase inhibitors.

Soriano V, Vispo E, de Mendoza C, Labarga P, Fernandez-Montero JV, Poveda E, TreviƱo A, Barreiro P.

Expert Opin Pharmacother. 2013 Jun;14(9):1161-70. doi: 10.1517/14656566.2013.795543. Epub 2013 Apr 27. Review.

PMID:
23621117
[PubMed - indexed for MEDLINE]
17.

Nucleoside analog inhibitors of hepatitis C virus replication.

Carroll SS, Olsen DB.

Infect Disord Drug Targets. 2006 Mar;6(1):17-29. Review.

PMID:
16787301
[PubMed - indexed for MEDLINE]
18.

Progress towards improving antiviral therapy for hepatitis C with hepatitis C virus polymerase inhibitors. Part I: Nucleoside analogues.

Brown NA.

Expert Opin Investig Drugs. 2009 Jun;18(6):709-25. doi: 10.1517/13543780902854194 . Review.

PMID:
19426125
[PubMed - indexed for MEDLINE]
19.

2'-deoxy-4'-azido nucleoside analogs are highly potent inhibitors of hepatitis C virus replication despite the lack of 2'-alpha-hydroxyl groups.

Klumpp K, Kalayanov G, Ma H, Le Pogam S, Leveque V, Jiang WR, Inocencio N, De Witte A, Rajyaguru S, Tai E, Chanda S, Irwin MR, Sund C, Winqist A, Maltseva T, Eriksson S, Usova E, Smith M, Alker A, Najera I, Cammack N, Martin JA, Johansson NG, Smith DB.

J Biol Chem. 2008 Jan 25;283(4):2167-75. Epub 2007 Nov 14.

PMID:
18003608
[PubMed - indexed for MEDLINE]
Free Article
20.

Sofosbuvir, a nucleotide polymerase inhibitor, for the treatment of chronic hepatitis C virus infection.

Herbst DA Jr, Reddy KR.

Expert Opin Investig Drugs. 2013 Apr;22(4):527-36. doi: 10.1517/13543784.2013.775246. Epub 2013 Mar 1. Review.

PMID:
23448131
[PubMed - indexed for MEDLINE]

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