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Results: 1 to 20 of 121

1.

Uncoupling and reactive oxygen species (ROS)--a double-edged sword for β-cell function? "Moderation in all things".

Collins S, Pi J, Yehuda-Shnaidman E.

Best Pract Res Clin Endocrinol Metab. 2012 Dec;26(6):753-8. doi: 10.1016/j.beem.2012.08.002. Epub 2012 Sep 18. Review.

PMID:
23168277
[PubMed - indexed for MEDLINE]
2.

Increasing uncoupling protein-2 in pancreatic beta cells does not alter glucose-induced insulin secretion but decreases production of reactive oxygen species.

Produit-Zengaffinen N, Davis-Lameloise N, Perreten H, Bécard D, Gjinovci A, Keller PA, Wollheim CB, Herrera P, Muzzin P, Assimacopoulos-Jeannet F.

Diabetologia. 2007 Jan;50(1):84-93. Epub 2006 Nov 28.

PMID:
17131143
[PubMed - indexed for MEDLINE]
3.

4-hydroxy-2-nonenal and uncoupling proteins: an approach for regulation of mitochondrial ROS production.

Echtay KS, Brand MD.

Redox Rep. 2007;12(1):26-9.

PMID:
17263904
[PubMed - indexed for MEDLINE]
4.

Reactive oxygen species and uncoupling protein 2 in pancreatic β-cell function.

Pi J, Collins S.

Diabetes Obes Metab. 2010 Oct;12 Suppl 2:141-8. doi: 10.1111/j.1463-1326.2010.01269.x. Review.

PMID:
21029311
[PubMed - indexed for MEDLINE]
5.

Autoregulation of free radicals via uncoupling protein control in pancreatic beta-cell mitochondria.

Heuett WJ, Periwal V.

Biophys J. 2010 Jan 20;98(2):207-17. doi: 10.1016/j.bpj.2009.10.012.

PMID:
20338842
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Uncoupling proteins and the control of mitochondrial reactive oxygen species production.

Mailloux RJ, Harper ME.

Free Radic Biol Med. 2011 Sep 15;51(6):1106-15. doi: 10.1016/j.freeradbiomed.2011.06.022. Epub 2011 Jun 24. Review.

PMID:
21762777
[PubMed - indexed for MEDLINE]
7.

Mitochondrial hormesis in pancreatic β cells: does uncoupling protein 2 play a role?

Li N, Stojanovski S, Maechler P.

Oxid Med Cell Longev. 2012;2012:740849. doi: 10.1155/2012/740849. Epub 2012 Sep 16. Review.

PMID:
23029600
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Uncoupling protein-2 (UCP2) induces mitochondrial proton leak and increases susceptibility of non-alcoholic steatohepatitis (NASH) liver to ischaemia-reperfusion injury.

Serviddio G, Bellanti F, Tamborra R, Rollo T, Capitanio N, Romano AD, Sastre J, Vendemiale G, Altomare E.

Gut. 2008 Jul;57(7):957-65. doi: 10.1136/gut.2007.147496. Epub 2008 Feb 28.

PMID:
18308829
[PubMed - indexed for MEDLINE]
9.

Glutathionylation state of uncoupling protein-2 and the control of glucose-stimulated insulin secretion.

Mailloux RJ, Fu A, Robson-Doucette C, Allister EM, Wheeler MB, Screaton R, Harper ME.

J Biol Chem. 2012 Nov 16;287(47):39673-85. doi: 10.1074/jbc.M112.393538. Epub 2012 Oct 3.

PMID:
23035124
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Mitochondrial UCP4 mediates an adaptive shift in energy metabolism and increases the resistance of neurons to metabolic and oxidative stress.

Liu D, Chan SL, de Souza-Pinto NC, Slevin JR, Wersto RP, Zhan M, Mustafa K, de Cabo R, Mattson MP.

Neuromolecular Med. 2006;8(3):389-414.

PMID:
16775390
[PubMed - indexed for MEDLINE]
11.

Mitochondrial proticity and ROS signaling: lessons from the uncoupling proteins.

Mailloux RJ, Harper ME.

Trends Endocrinol Metab. 2012 Sep;23(9):451-8. doi: 10.1016/j.tem.2012.04.004. Epub 2012 May 15. Review.

PMID:
22591987
[PubMed - indexed for MEDLINE]
12.

Mitochondrial Ca2+, the secret behind the function of uncoupling proteins 2 and 3?

Graier WF, Trenker M, Malli R.

Cell Calcium. 2008 Jul;44(1):36-50. doi: 10.1016/j.ceca.2008.01.001. Epub 2008 Feb 20.

PMID:
18282596
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Uncoupling protein-3 lowers reactive oxygen species production in isolated mitochondria.

Toime LJ, Brand MD.

Free Radic Biol Med. 2010 Aug 15;49(4):606-11. doi: 10.1016/j.freeradbiomed.2010.05.010. Epub 2010 May 21.

PMID:
20493945
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Type 1 diabetic akita mouse hearts are insulin sensitive but manifest structurally abnormal mitochondria that remain coupled despite increased uncoupling protein 3.

Bugger H, Boudina S, Hu XX, Tuinei J, Zaha VG, Theobald HA, Yun UJ, McQueen AP, Wayment B, Litwin SE, Abel ED.

Diabetes. 2008 Nov;57(11):2924-32. doi: 10.2337/db08-0079. Epub 2008 Aug 4.

PMID:
18678617
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Cold tolerance of UCP1-ablated mice: a skeletal muscle mitochondria switch toward lipid oxidation with marked UCP3 up-regulation not associated with increased basal, fatty acid- or ROS-induced uncoupling or enhanced GDP effects.

Shabalina IG, Hoeks J, Kramarova TV, Schrauwen P, Cannon B, Nedergaard J.

Biochim Biophys Acta. 2010 Jun-Jul;1797(6-7):968-80. doi: 10.1016/j.bbabio.2010.02.033. Epub 2010 Mar 19.

PMID:
20227385
[PubMed - indexed for MEDLINE]
Free Article
16.

Mitochondrial ('mild') uncoupling and ROS production: physiologically relevant or not?

Shabalina IG, Nedergaard J.

Biochem Soc Trans. 2011 Oct;39(5):1305-9. doi: 10.1042/BST0391305. Review.

PMID:
21936806
[PubMed - indexed for MEDLINE]
17.

Mitochondrial uncoupling and lifespan.

Mookerjee SA, Divakaruni AS, Jastroch M, Brand MD.

Mech Ageing Dev. 2010 Jul-Aug;131(7-8):463-72. doi: 10.1016/j.mad.2010.03.010. Epub 2010 Apr 2. Review.

PMID:
20363244
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Regulation of mitochondrial uncoupling respiration during exercise in rat heart: role of reactive oxygen species (ROS) and uncoupling protein 2.

Bo H, Jiang N, Ma G, Qu J, Zhang G, Cao D, Wen L, Liu S, Ji LL, Zhang Y.

Free Radic Biol Med. 2008 Apr 1;44(7):1373-81. doi: 10.1016/j.freeradbiomed.2007.12.033. Epub 2008 Jan 4.

PMID:
18226608
[PubMed - indexed for MEDLINE]
19.

Respiratory uncoupling by UCP1 and UCP2 and superoxide generation in endothelial cell mitochondria.

Fink BD, Reszka KJ, Herlein JA, Mathahs MM, Sivitz WI.

Am J Physiol Endocrinol Metab. 2005 Jan;288(1):E71-9. Epub 2004 Aug 31.

PMID:
15339748
[PubMed - indexed for MEDLINE]
Free Article
20.

Mitochondria contribute to LPS-induced MAPK activation via uncoupling protein UCP2 in macrophages.

Emre Y, Hurtaud C, Nübel T, Criscuolo F, Ricquier D, Cassard-Doulcier AM.

Biochem J. 2007 Mar 1;402(2):271-8.

PMID:
17073824
[PubMed - indexed for MEDLINE]
Free PMC Article
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