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Results: 1 to 20 of 110

1.

Function annotation of hepatic retinoid x receptor α based on genome-wide DNA binding and transcriptome profiling.

Zhan Q, Fang Y, He Y, Liu HX, Fang J, Wan YJ.

PLoS One. 2012;7(11):e50013. doi: 10.1371/journal.pone.0050013. Epub 2012 Nov 15.

PMID:
23166811
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Sexually dimorphic genome-wide binding of retinoid X receptor alpha (RXRα) determines male-female differences in the expression of hepatic lipid processing genes in mice.

Kosters A, Sun D, Wu H, Tian F, Felix JC, Li W, Karpen SJ.

PLoS One. 2013 Aug 19;8(8):e71538. doi: 10.1371/journal.pone.0071538. eCollection 2013.

PMID:
23977068
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

The role of retinoic acid in hepatic lipid homeostasis defined by genomic binding and transcriptome profiling.

He Y, Gong L, Fang Y, Zhan Q, Liu HX, Lu Y, Guo GL, Lehman-McKeeman L, Fang J, Wan YJ.

BMC Genomics. 2013 Aug 28;14:575. doi: 10.1186/1471-2164-14-575.

PMID:
23981290
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Gene-specific alterations of hepatic gene expression by ligand activation or hepatocyte-selective inhibition of retinoid X receptor-α signalling during inflammation.

Kosters A, Tian F, Wan YJ, Karpen SJ.

Liver Int. 2012 Feb;32(2):321-30. doi: 10.1111/j.1478-3231.2011.02664.x. Epub 2011 Nov 1. Erratum in: Liver Int. 2013 Apr;33(4):652. Wan, Yvonne Yu-Jie [corrected to Wan, Yu-Jui Yvonne].

PMID:
22098603
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Mechanisms of resistance of hepatocyte retinoid X receptor alpha-null mice to WY-14,643-induced hepatocyte proliferation and cholestasis.

Gyamfi MA, Wan YJ.

J Biol Chem. 2009 Apr 3;284(14):9321-30. doi: 10.1074/jbc.M808861200. Epub 2009 Jan 27.

PMID:
19176532
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Heme-binding to the nuclear receptor retinoid X receptor alpha (RXRalpha) leads to the inhibition of the transcriptional activity.

Gotoh S, Ohgari Y, Nakamura T, Osumi T, Taketani S.

Gene. 2008 Nov 1;423(2):207-14. doi: 10.1016/j.gene.2008.07.006. Epub 2008 Jul 15.

PMID:
18675890
[PubMed - indexed for MEDLINE]
7.

Genome-wide analysis of FoxO1 binding in hepatic chromatin: potential involvement of FoxO1 in linking retinoid signaling to hepatic gluconeogenesis.

Shin DJ, Joshi P, Hong SH, Mosure K, Shin DG, Osborne TF.

Nucleic Acids Res. 2012 Dec;40(22):11499-509. doi: 10.1093/nar/gks932. Epub 2012 Oct 12.

PMID:
23066095
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Peroxisome proliferator-activated receptor alpha-mediated pathways are altered in hepatocyte-specific retinoid X receptor alpha-deficient mice.

Wan YJ, Cai Y, Lungo W, Fu P, Locker J, French S, Sucov HM.

J Biol Chem. 2000 Sep 8;275(36):28285-90.

PMID:
10866995
[PubMed - indexed for MEDLINE]
Free Article
9.

Genome-wide profiling of liver X receptor, retinoid X receptor, and peroxisome proliferator-activated receptor α in mouse liver reveals extensive sharing of binding sites.

Boergesen M, Pedersen TÅ, Gross B, van Heeringen SJ, Hagenbeek D, Bindesbøll C, Caron S, Lalloyer F, Steffensen KR, Nebb HI, Gustafsson JÅ, Stunnenberg HG, Staels B, Mandrup S.

Mol Cell Biol. 2012 Feb;32(4):852-67. doi: 10.1128/MCB.06175-11. Epub 2011 Dec 12.

PMID:
22158963
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Binding specificity and modulation of the ApoA-I promoter activity by homo- and heterodimers of nuclear receptors.

Tzameli I, Zannis VI.

J Biol Chem. 1996 Apr 5;271(14):8402-15.

PMID:
8626539
[PubMed - indexed for MEDLINE]
Free Article
11.

Inflammatory mediators increase SUMOylation of retinoid X receptor α in a c-Jun N-terminal kinase-dependent manner in human hepatocellular carcinoma cells.

Schneider Aguirre R, Karpen SJ.

Mol Pharmacol. 2013 Aug;84(2):218-26. doi: 10.1124/mol.113.085555. Epub 2013 May 20.

PMID:
23690070
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Farnesoid X receptor directly regulates xenobiotic detoxification genes in the long-lived Little mice.

Jiang Y, Jin J, Iakova P, Hernandez JC, Jawanmardi N, Sullivan E, Guo GL, Timchenko NA, Darlington GJ.

Mech Ageing Dev. 2013 Sep;134(9):407-15. doi: 10.1016/j.mad.2013.08.003. Epub 2013 Sep 2.

PMID:
24007921
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Ligand-activated PPARbeta efficiently represses the induction of LXR-dependent promoter activity through competition with RXR.

Matsusue K, Miyoshi A, Yamano S, Gonzalez FJ.

Mol Cell Endocrinol. 2006 Aug 15;256(1-2):23-33.

PMID:
16806672
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Retinoid X receptor alpha regulates glutathione homeostasis and xenobiotic detoxification processes in mouse liver.

Wu Y, Zhang X, Bardag-Gorce F, Robel RC, Aguilo J, Chen L, Zeng Y, Hwang K, French SW, Lu SC, Wan YJ.

Mol Pharmacol. 2004 Mar;65(3):550-7.

PMID:
14978233
[PubMed - indexed for MEDLINE]
Free Article
15.

Downregulation of liver X receptor-alpha in mouse kidney and HK-2 proximal tubular cells by LPS and cytokines.

Wang Y, Moser AH, Shigenaga JK, Grunfeld C, Feingold KR.

J Lipid Res. 2005 Nov;46(11):2377-87. Epub 2005 Aug 16.

PMID:
16106051
[PubMed - indexed for MEDLINE]
Free Article
16.

Coordinated control of bile acids and lipogenesis through FXR-dependent regulation of fatty acid synthase.

Matsukuma KE, Bennett MK, Huang J, Wang L, Gil G, Osborne TF.

J Lipid Res. 2006 Dec;47(12):2754-61. Epub 2006 Sep 6.

PMID:
16957179
[PubMed - indexed for MEDLINE]
Free Article
17.

Redundant roles for cJun-N-terminal kinase 1 and 2 in interleukin-1beta-mediated reduction and modification of murine hepatic nuclear retinoid X receptor alpha.

Kosters A, White DD, Sun H, Thevananther S, Karpen SJ.

J Hepatol. 2009 Nov;51(5):898-908. doi: 10.1016/j.jhep.2009.06.029. Epub 2009 Aug 20.

PMID:
19767119
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Dissecting the retinoid-induced differentiation of F9 embryonal stem cells by integrative genomics.

Mendoza-Parra MA, Walia M, Sankar M, Gronemeyer H.

Mol Syst Biol. 2011 Oct 11;7:538. doi: 10.1038/msb.2011.73.

PMID:
21988834
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Retinoid X receptor regulates Nur77/TR3-dependent apoptosis [corrected] by modulating its nuclear export and mitochondrial targeting.

Cao X, Liu W, Lin F, Li H, Kolluri SK, Lin B, Han YH, Dawson MI, Zhang XK.

Mol Cell Biol. 2004 Nov;24(22):9705-25. Erratum in: Mol Cell Biol. 2005 Jan;25(1):524.

PMID:
15509776
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Nuclear export of retinoid X receptor alpha in response to interleukin-1beta-mediated cell signaling: roles for JNK and SER260.

Zimmerman TL, Thevananther S, Ghose R, Burns AR, Karpen SJ.

J Biol Chem. 2006 Jun 2;281(22):15434-40. Epub 2006 Mar 21.

PMID:
16551633
[PubMed - indexed for MEDLINE]
Free Article

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