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Items: 1 to 20 of 115

1.

Multiple novel alternative splicing forms of FBXW7α have a translational modulatory function and show specific alteration in human cancer.

Liu Y, Ren S, Castellanos-Martin A, Perez-Losada J, Kwon YW, Huang Y, Wang Z, Abad M, Cruz-Hernandez JJ, Rodriguez CA, Sun Y, Mao JH.

PLoS One. 2012;7(11):e49453. doi: 10.1371/journal.pone.0049453. Epub 2012 Nov 14.

2.

The FBXW7 beta-form is suppressed in human glioma cells.

Gu Z, Inomata K, Ishizawa K, Horii A.

Biochem Biophys Res Commun. 2007 Mar 23;354(4):992-8. Epub 2007 Jan 24.

PMID:
17274947
3.

Inactivation of FBXW7/hCDC4-β expression by promoter hypermethylation is associated with favorable prognosis in primary breast cancer.

Akhoondi S, Lindström L, Widschwendter M, Corcoran M, Bergh J, Spruck C, Grandér D, Sangfelt O.

Breast Cancer Res. 2010;12(6):R105. doi: 10.1186/bcr2788. Epub 2010 Dec 1.

4.

FBXW7/hCDC4 is a general tumor suppressor in human cancer.

Akhoondi S, Sun D, von der Lehr N, Apostolidou S, Klotz K, Maljukova A, Cepeda D, Fiegl H, Dafou D, Marth C, Mueller-Holzner E, Corcoran M, Dagnell M, Nejad SZ, Nayer BN, Zali MR, Hansson J, Egyhazi S, Petersson F, Sangfelt P, Nordgren H, Grander D, Reed SI, Widschwendter M, Sangfelt O, Spruck C.

Cancer Res. 2007 Oct 1;67(19):9006-12. Erratum in: Cancer Res. 2008 Feb 15;68(4):1245. Dofou, Dimitra [corrected to Dafou, Dimitra].

5.

MYC, FBXW7 and TP53 copy number variation and expression in gastric cancer.

Calcagno DQ, Freitas VM, Leal MF, de Souza CR, Demachki S, Montenegro R, Assumpção PP, Khayat AS, Smith Mde A, dos Santos AK, Burbano RR.

BMC Gastroenterol. 2013 Sep 23;13:141. doi: 10.1186/1471-230X-13-141.

6.

Reduced expression of ubiquitin ligase FBXW7 mRNA is associated with poor prognosis in breast cancer patients.

Ibusuki M, Yamamoto Y, Shinriki S, Ando Y, Iwase H.

Cancer Sci. 2011 Feb;102(2):439-45. doi: 10.1111/j.1349-7006.2010.01801.x. Epub 2010 Dec 7.

7.

The Fbxw7/hCdc4 tumor suppressor in human cancer.

Tan Y, Sangfelt O, Spruck C.

Cancer Lett. 2008 Nov 18;271(1):1-12. doi: 10.1016/j.canlet.2008.04.036. Epub 2008 Jun 9. Review.

PMID:
18541364
8.
9.

MicroRNA-223 functions as an oncogene in human gastric cancer by targeting FBXW7/hCdc4.

Li J, Guo Y, Liang X, Sun M, Wang G, De W, Wu W.

J Cancer Res Clin Oncol. 2012 May;138(5):763-74. doi: 10.1007/s00432-012-1154-x. Epub 2012 Jan 22.

PMID:
22270966
10.

Loss of FBXW7, a cell cycle regulating gene, in colorectal cancer: clinical significance.

Iwatsuki M, Mimori K, Ishii H, Yokobori T, Takatsuno Y, Sato T, Toh H, Onoyama I, Nakayama KI, Baba H, Mori M.

Int J Cancer. 2010 Apr 15;126(8):1828-37. doi: 10.1002/ijc.24879.

11.

Role of Fbxw7 expression in hepatocellular carcinoma and adjacent non-tumor liver tissue.

Imura S, Tovuu LO, Utsunomiya T, Morine Y, Ikemoto T, Arakawa Y, Kanamoto M, Iwahashi S, Saito Y, Takasu C, Yamada S, Ishikawa D, Bando Y, Shimada M.

J Gastroenterol Hepatol. 2014 Oct;29(10):1822-9. doi: 10.1111/jgh.12623.

PMID:
24731221
12.

The tumor suppressor gene FBXW7 is disrupted by a constitutional t(3;4)(q21;q31) in a patient with renal cell cancer.

Kuiper RP, Vreede L, Venkatachalam R, Ricketts C, Kamping E, Verwiel E, Govaerts L, Debiec-Rychter M, Lerut E, van Erp F, Hoogerbrugge N, van Kempen L, Schoenmakers EF, Bonne A, Maher ER, Geurts van Kessel A.

Cancer Genet Cytogenet. 2009 Dec;195(2):105-11. doi: 10.1016/j.cancergencyto.2009.07.001.

PMID:
19963109
13.

Expression of mouse Fbxw7 isoforms is regulated in a cell cycle- or p53-dependent manner.

Matsumoto A, Onoyama I, Nakayama KI.

Biochem Biophys Res Commun. 2006 Nov 10;350(1):114-9. Epub 2006 Sep 12.

PMID:
16989775
14.

Copy number loss of FBXW7 is related to gene expression and poor prognosis in esophageal squamous cell carcinoma.

Yokobori T, Mimori K, Iwatsuki M, Ishii H, Tanaka F, Sato T, Toh H, Sudo T, Iwaya T, Tanaka Y, Onoyama I, Kuwano H, Nakayama KI, Mori M.

Int J Oncol. 2012 Jul;41(1):253-9. doi: 10.3892/ijo.2012.1436. Epub 2012 Apr 19.

PMID:
22576686
15.

FBXW7 influences murine intestinal homeostasis and cancer, targeting Notch, Jun, and DEK for degradation.

Babaei-Jadidi R, Li N, Saadeddin A, Spencer-Dene B, Jandke A, Muhammad B, Ibrahim EE, Muraleedharan R, Abuzinadah M, Davis H, Lewis A, Watson S, Behrens A, Tomlinson I, Nateri AS.

J Exp Med. 2011 Feb 14;208(2):295-312. doi: 10.1084/jem.20100830. Epub 2011 Jan 31.

16.

Fbxw7 contributes to tumor suppression by targeting multiple proteins for ubiquitin-dependent degradation.

Fujii Y, Yada M, Nishiyama M, Kamura T, Takahashi H, Tsunematsu R, Susaki E, Nakagawa T, Matsumoto A, Nakayama KI.

Cancer Sci. 2006 Aug;97(8):729-36.

17.

p53-Altered FBXW7 expression determines poor prognosis in gastric cancer cases.

Yokobori T, Mimori K, Iwatsuki M, Ishii H, Onoyama I, Fukagawa T, Kuwano H, Nakayama KI, Mori M.

Cancer Res. 2009 May 1;69(9):3788-94. doi: 10.1158/0008-5472.CAN-08-2846. Epub 2009 Apr 14.

18.

Fbxw7 acts as an E3 ubiquitin ligase that targets c-Myb for nemo-like kinase (NLK)-induced degradation.

Kanei-Ishii C, Nomura T, Takagi T, Watanabe N, Nakayama KI, Ishii S.

J Biol Chem. 2008 Nov 7;283(45):30540-8. doi: 10.1074/jbc.M804340200. Epub 2008 Sep 2.

19.

FBXW7 and DNA copy number instability.

Byrd KN, Huey B, Roydasgupta R, Fridlyand J, Snijders AM, Albertson DG.

Breast Cancer Res Treat. 2008 May;109(1):47-54. Epub 2007 Jun 23.

PMID:
17588203
20.

Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene.

Mao JH, Perez-Losada J, Wu D, Delrosario R, Tsunematsu R, Nakayama KI, Brown K, Bryson S, Balmain A.

Nature. 2004 Dec 9;432(7018):775-9.

PMID:
15592418
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