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Mice fed with a high fat diet show a decrease in the expression of "toll like receptor (TLR)2 and TLR6 mRNAs in adipose and hepatic tissues.

Betanzos-Cabrera G, Estrada-Luna D, Belefant-Miller H, Cancino-Díaz JC.

Nutr Hosp. 2012 Jul-Aug;27(4):1196-203. doi: 10.3305/nh.2012.27.4.5842.


Carvacrol prevents diet-induced obesity by modulating gene expressions involved in adipogenesis and inflammation in mice fed with high-fat diet.

Cho S, Choi Y, Park S, Park T.

J Nutr Biochem. 2012 Feb;23(2):192-201. doi: 10.1016/j.jnutbio.2010.11.016. Epub 2011 Mar 29.


Dietary saturated fatty acids prime the NLRP3 inflammasome via TLR4 in dendritic cells-implications for diet-induced insulin resistance.

Reynolds CM, McGillicuddy FC, Harford KA, Finucane OM, Mills KH, Roche HM.

Mol Nutr Food Res. 2012 Aug;56(8):1212-22. doi: 10.1002/mnfr.201200058. Epub 2012 Jun 15.


Inflammatory role of Toll-like receptors in human and murine adipose tissue.

Poulain-Godefroy O, Le Bacquer O, Plancq P, Lecoeur C, Pattou F, Frühbeck G, Froguel P.

Mediators Inflamm. 2010;2010:823486. doi: 10.1155/2010/823486. Epub 2010 Mar 22.


Obesity activates toll-like receptor-mediated proinflammatory signaling cascades in the adipose tissue of mice.

Kim SJ, Choi Y, Choi YH, Park T.

J Nutr Biochem. 2012 Feb;23(2):113-22. doi: 10.1016/j.jnutbio.2010.10.012. Epub 2011 Mar 16.


Dietary capsaicin reduces obesity-induced insulin resistance and hepatic steatosis in obese mice fed a high-fat diet.

Kang JH, Goto T, Han IS, Kawada T, Kim YM, Yu R.

Obesity (Silver Spring). 2010 Apr;18(4):780-7. doi: 10.1038/oby.2009.301. Epub 2009 Oct 1.


Synergism of toll-like receptor 2 (TLR2), TLR4, and TLR6 ligation on the production of tumor necrosis factor (TNF)-alpha in a spontaneous arthritis animal model of interleukin (IL)-1 receptor antagonist-deficient mice.

Jung YO, Cho ML, Lee SY, Oh HJ, Park JS, Park MK, Park MJ, Ju JH, Kim SI, Park SH, Kim HY, Min JK.

Immunol Lett. 2009 Apr 27;123(2):138-43. doi: 10.1016/j.imlet.2009.03.004. Epub 2009 Mar 21.


Green tomato extract attenuates high-fat-diet-induced obesity through activation of the AMPK pathway in C57BL/6 mice.

Choi KM, Lee YS, Shin DM, Lee S, Yoo KS, Lee MK, Lee JH, Kim SY, Lee YM, Hong JT, Yun YP, Yoo HS.

J Nutr Biochem. 2013 Jan;24(1):335-42. doi: 10.1016/j.jnutbio.2012.06.018. Epub 2012 Sep 10.


Metabolic and immunomodulatory effects of n-3 fatty acids are different in mesenteric and epididymal adipose tissue of diet-induced obese mice.

Ludwig T, Worsch S, Heikenwalder M, Daniel H, Hauner H, Bader BL.

Am J Physiol Endocrinol Metab. 2013 Jun 1;304(11):E1140-56. doi: 10.1152/ajpendo.00171.2012. Epub 2013 Mar 12.


High fat diet-induced gut microbiota exacerbates inflammation and obesity in mice via the TLR4 signaling pathway.

Kim KA, Gu W, Lee IA, Joh EH, Kim DH.

PLoS One. 2012;7(10):e47713. doi: 10.1371/journal.pone.0047713. Epub 2012 Oct 16.


Adipose tissue inflammation contributes to short-term high-fat diet-induced hepatic insulin resistance.

Wiedemann MS, Wueest S, Item F, Schoenle EJ, Konrad D.

Am J Physiol Endocrinol Metab. 2013 Aug 1;305(3):E388-95. doi: 10.1152/ajpendo.00179.2013. Epub 2013 Jun 4.


TNFα gene knockout differentially affects lipid deposition in liver and skeletal muscle of high-fat-diet mice.

Salles J, Tardif N, Landrier JF, Mothe-Satney I, Guillet C, Boue-Vaysse C, Combaret L, Giraudet C, Patrac V, Bertrand-Michel J, Denis P, Chardigny JM, Boirie Y, Walrand S.

J Nutr Biochem. 2012 Dec;23(12):1685-93. doi: 10.1016/j.jnutbio.2011.12.001. Epub 2012 Mar 29.


Toll-like receptor 2-deficient mice are protected from insulin resistance and beta cell dysfunction induced by a high-fat diet.

Ehses JA, Meier DT, Wueest S, Rytka J, Boller S, Wielinga PY, Schraenen A, Lemaire K, Debray S, Van Lommel L, Pospisilik JA, Tschopp O, Schultze SM, Malipiero U, Esterbauer H, Ellingsgaard H, Rütti S, Schuit FC, Lutz TA, Böni-Schnetzler M, Konrad D, Donath MY.

Diabetologia. 2010 Aug;53(8):1795-806. doi: 10.1007/s00125-010-1747-3. Epub 2010 Apr 21.


Toll-like receptors 1 and 6 are involved in TLR2-mediated macrophage activation by hepatitis C virus core and NS3 proteins.

Chang S, Dolganiuc A, Szabo G.

J Leukoc Biol. 2007 Sep;82(3):479-87. Epub 2007 Jun 26.


Effects of a Lactobacillus paracasei B21060 based synbiotic on steatosis, insulin signaling and toll-like receptor expression in rats fed a high-fat diet.

Raso GM, Simeoli R, Iacono A, Santoro A, Amero P, Paciello O, Russo R, D'Agostino G, Di Costanzo M, Canani RB, Calignano A, Meli R.

J Nutr Biochem. 2014 Jan;25(1):81-90. doi: 10.1016/j.jnutbio.2013.09.006. Epub 2013 Oct 10.


Diet-induced obesity has a differential effect on adipose tissue and macrophage inflammatory responses of young and old mice.

Wu D, Ren Z, Pae M, Han SN, Meydani SN.

Biofactors. 2013 May-Jun;39(3):326-33. doi: 10.1002/biof.1075. Epub 2013 Jan 24.


Regulation of PPAR gamma gene expression by nutrition and obesity in rodents.

Vidal-Puig A, Jimenez-Liñan M, Lowell BB, Hamann A, Hu E, Spiegelman B, Flier JS, Moller DE.

J Clin Invest. 1996 Jun 1;97(11):2553-61.


Deficiency for costimulatory receptor 4-1BB protects against obesity-induced inflammation and metabolic disorders.

Kim CS, Kim JG, Lee BJ, Choi MS, Choi HS, Kawada T, Lee KU, Yu R.

Diabetes. 2011 Dec;60(12):3159-68. doi: 10.2337/db10-1805. Epub 2011 Oct 13.


Korean red ginseng (Panax ginseng) prevents obesity by inhibiting angiogenesis in high fat diet-induced obese C57BL/6J mice.

Lee H, Park D, Yoon M.

Food Chem Toxicol. 2013 Mar;53:402-8. doi: 10.1016/j.fct.2012.11.052. Epub 2012 Dec 8.

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