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Results: 1 to 20 of 92

1.

Involvement of the Ca2+-responsive transactivator in high glucose-induced β-cell apoptosis.

Men X, Peng L, Wang H, Zhang W, Xu S, Fang Q, Liu H, Yang W, Lou J.

J Endocrinol. 2013 Jan 18;216(2):231-43. doi: 10.1530/JOE-12-0286. Print 2013 Feb.

PMID:
23160962
[PubMed - indexed for MEDLINE]
Free Article
2.

TRIB3 [corrected] is implicated in glucotoxicity- and endoplasmic reticulum-stress-induced [corrected] beta-cell apoptosis.

Qian B, Wang H, Men X, Zhang W, Cai H, Xu S, Xu Y, Ye L, Wollheim CB, Lou J.

J Endocrinol. 2008 Dec;199(3):407-16. doi: 10.1677/JOE-08-0331. Epub 2008 Sep 25. Erratum in: J Endocrinol. 2009 Dec;203(3):399. J Endocrinol. 2009 Feb;200(2):243.

PMID:
18818302
[PubMed - indexed for MEDLINE]
Free Article
3.

α-lipoic acid inhibits high glucose-induced apoptosis in HIT-T15 cells.

Yang Y, Wang W, Liu Y, Guo T, Chen P, Ma K, Zhou C.

Dev Growth Differ. 2012 Jun;54(5):557-65. doi: 10.1111/j.1440-169X.2012.01356.x. Epub 2012 May 24.

PMID:
22620683
[PubMed - indexed for MEDLINE]
4.

Long-term exposure of INS-1 rat insulinoma cells to linoleic acid and glucose in vitro affects cell viability and function through mitochondrial-mediated pathways.

Tuo Y, Wang D, Li S, Chen C.

Endocrine. 2011 Apr;39(2):128-38. doi: 10.1007/s12020-010-9432-3. Epub 2010 Dec 15.

PMID:
21161439
[PubMed - indexed for MEDLINE]
5.

High glucose induces suppression of insulin signalling and apoptosis via upregulation of endogenous IL-1beta and suppressor of cytokine signalling-1 in mouse pancreatic beta cells.

Venieratos PD, Drossopoulou GI, Kapodistria KD, Tsilibary EC, Kitsiou PV.

Cell Signal. 2010 May;22(5):791-800. doi: 10.1016/j.cellsig.2010.01.003. Epub 2010 Jan 11.

PMID:
20067833
[PubMed - indexed for MEDLINE]
6.

The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients.

Marchetti P, Bugliani M, Lupi R, Marselli L, Masini M, Boggi U, Filipponi F, Weir GC, Eizirik DL, Cnop M.

Diabetologia. 2007 Dec;50(12):2486-94. Epub 2007 Sep 30.

PMID:
17906960
[PubMed - indexed for MEDLINE]
7.

SLC30A3 responds to glucose- and zinc variations in beta-cells and is critical for insulin production and in vivo glucose-metabolism during beta-cell stress.

Smidt K, Jessen N, Petersen AB, Larsen A, Magnusson N, Jeppesen JB, Stoltenberg M, Culvenor JG, Tsatsanis A, Brock B, Schmitz O, Wogensen L, Bush AI, Rungby J.

PLoS One. 2009 May 25;4(5):e5684. doi: 10.1371/journal.pone.0005684.

PMID:
19492079
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Adiponectin reduces glucotoxicity-induced apoptosis of INS-1 rat insulin-secreting cells on a microfluidic chip.

Lin P, Chen L, Li D, Liu J, Yang N, Sun Y, Xu Y, Fu Y, Hou X.

Tohoku J Exp Med. 2009 Jan;217(1):59-65.

PMID:
19155609
[PubMed - indexed for MEDLINE]
Free Article
9.

Prednisolone-induced beta cell dysfunction is associated with impaired endoplasmic reticulum homeostasis in INS-1E cells.

Linssen MM, van Raalte DH, Toonen EJ, Alkema W, van der Zon GC, Dokter WH, Diamant M, Guigas B, Ouwens DM.

Cell Signal. 2011 Nov;23(11):1708-15. doi: 10.1016/j.cellsig.2011.06.002. Epub 2011 Jun 13.

PMID:
21689745
[PubMed - indexed for MEDLINE]
10.

Crucial roles of neuronatin in insulin secretion and high glucose-induced apoptosis in pancreatic beta-cells.

Joe MK, Lee HJ, Suh YH, Han KL, Lim JH, Song J, Seong JK, Jung MH.

Cell Signal. 2008 May;20(5):907-15. doi: 10.1016/j.cellsig.2008.01.005. Epub 2008 Jan 18.

PMID:
18289831
[PubMed - indexed for MEDLINE]
11.

Overexpression of the coactivator bridge-1 results in insulin deficiency and diabetes.

Volinic JL, Lee JH, Eto K, Kaur V, Thomas MK.

Mol Endocrinol. 2006 Jan;20(1):167-82. Epub 2005 Aug 11.

PMID:
16099819
[PubMed - indexed for MEDLINE]
12.

Leptin decreases apoptosis and alters BCL-2 : Bax ratio in clonal rodent pancreatic beta-cells.

Brown JE, Dunmore SJ.

Diabetes Metab Res Rev. 2007 Sep;23(6):497-502.

PMID:
17318810
[PubMed - indexed for MEDLINE]
13.

Insulin counteracts glucotoxic effects by suppressing thioredoxin-interacting protein production in INS-1E beta cells and in Psammomys obesus pancreatic islets.

Shaked M, Ketzinel-Gilad M, Ariav Y, Cerasi E, Kaiser N, Leibowitz G.

Diabetologia. 2009 Apr;52(4):636-44. doi: 10.1007/s00125-009-1274-2. Epub 2009 Feb 13.

PMID:
19214472
[PubMed - indexed for MEDLINE]
14.

Modulation of palmitate-induced endoplasmic reticulum stress and apoptosis in pancreatic β-cells by stearoyl-CoA desaturase and Elovl6.

Green CD, Olson LK.

Am J Physiol Endocrinol Metab. 2011 Apr;300(4):E640-9. doi: 10.1152/ajpendo.00544.2010. Epub 2011 Jan 25.

PMID:
21266672
[PubMed - indexed for MEDLINE]
Free Article
15.

Dynamin-related protein 1 mediates high glucose induced pancreatic beta cell apoptosis.

Men X, Wang H, Li M, Cai H, Xu S, Zhang W, Xu Y, Ye L, Yang W, Wollheim CB, Lou J.

Int J Biochem Cell Biol. 2009 Apr;41(4):879-90. doi: 10.1016/j.biocel.2008.08.031. Epub 2008 Sep 2.

PMID:
18805504
[PubMed - indexed for MEDLINE]
16.

Diazoxide prevents diabetes through inhibiting pancreatic beta-cells from apoptosis via Bcl-2/Bax rate and p38-beta mitogen-activated protein kinase.

Huang Q, Bu S, Yu Y, Guo Z, Ghatnekar G, Bu M, Yang L, Lu B, Feng Z, Liu S, Wang F.

Endocrinology. 2007 Jan;148(1):81-91. Epub 2006 Oct 19.

PMID:
17053028
[PubMed - indexed for MEDLINE]
17.

ERp46 is reduced by high glucose and regulates insulin content in pancreatic beta-cells.

Alberti A, Karamessinis P, Peroulis M, Kypreou K, Kavvadas P, Pagakis S, Politis PK, Charonis A.

Am J Physiol Endocrinol Metab. 2009 Sep;297(3):E812-21. doi: 10.1152/ajpendo.00053.2009. Epub 2009 Jul 21.

PMID:
19622788
[PubMed - indexed for MEDLINE]
Free Article
18.

The effect of chromium on rat insulinoma cells in high glucose conditions.

Kwon MJ, Chung HS, Yoon CS, Ko JH, Jun HJ, Kim TK, Lee SH, Ko KS, Rhee BD, Kim MK, Park JH.

Life Sci. 2010 Sep 25;87(13-14):401-4. doi: 10.1016/j.lfs.2010.08.001. Epub 2010 Aug 17.

PMID:
20723550
[PubMed - indexed for MEDLINE]
19.

Chronic exposure to free fatty acids or high glucose induces apoptosis in rat pancreatic islets: possible role of oxidative stress.

Piro S, Anello M, Di Pietro C, Lizzio MN, Patanè G, Rabuazzo AM, Vigneri R, Purrello M, Purrello F.

Metabolism. 2002 Oct;51(10):1340-7.

PMID:
12370856
[PubMed - indexed for MEDLINE]
20.

Transcription factor 7-like 2 regulates beta-cell survival and function in human pancreatic islets.

Shu L, Sauter NS, Schulthess FT, Matveyenko AV, Oberholzer J, Maedler K.

Diabetes. 2008 Mar;57(3):645-53. Epub 2007 Dec 10.

PMID:
18071026
[PubMed - indexed for MEDLINE]
Free Article

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