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Items: 1 to 20 of 100

1.

Lack of Sir2 increases acetate consumption and decreases extracellular pro-aging factors.

Casatta N, Porro A, Orlandi I, Brambilla L, Vai M.

Biochim Biophys Acta. 2013 Mar;1833(3):593-601. doi: 10.1016/j.bbamcr.2012.11.008. Epub 2012 Nov 16.

2.

Wine yeast sirtuins and Gcn5p control aging and metabolism in a natural growth medium.

Orozco H, Matallana E, Aranda A.

Mech Ageing Dev. 2012 May;133(5):348-58. doi: 10.1016/j.mad.2012.03.013. Epub 2012 Apr 2.

PMID:
22738658
3.

Genetic manipulation of longevity-related genes as a tool to regulate yeast life span and metabolite production during winemaking.

Orozco H, Matallana E, Aranda A.

Microb Cell Fact. 2013 Jan 2;12:1. doi: 10.1186/1475-2859-12-1.

4.

Growth phase-dependent roles of Sir2 in oxidative stress resistance and chronological lifespan in yeast.

Kang WK, Kim YH, Kim BS, Kim JY.

J Microbiol. 2014 Aug;52(8):652-8. doi: 10.1007/s12275-014-4173-2. Epub 2014 Jul 5.

PMID:
24997552
5.

Ethanol and acetate acting as carbon/energy sources negatively affect yeast chronological aging.

Orlandi I, Ronzulli R, Casatta N, Vai M.

Oxid Med Cell Longev. 2013;2013:802870. doi: 10.1155/2013/802870. Epub 2013 Aug 25.

6.

Sir2-dependent asymmetric segregation of damaged proteins in ubp10 null mutants is independent of genomic silencing.

Orlandi I, Bettiga M, Alberghina L, Nyström T, Vai M.

Biochim Biophys Acta. 2010 May;1803(5):630-8. doi: 10.1016/j.bbamcr.2010.02.009. Epub 2010 Mar 4.

7.

Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration.

Lin SJ, Kaeberlein M, Andalis AA, Sturtz LA, Defossez PA, Culotta VC, Fink GR, Guarente L.

Nature. 2002 Jul 18;418(6895):344-8.

PMID:
12124627
8.

The enigmatic role of Sir2 in aging.

Kennedy BK, Smith ED, Kaeberlein M.

Cell. 2005 Nov 18;123(4):548-50.

9.

NQR1 controls lifespan by regulating the promotion of respiratory metabolism in yeast.

Jiménez-Hidalgo M, Santos-Ocaña C, Padilla S, Villalba JM, López-Lluch G, Martín-Montalvo A, Minor RK, Sinclair DA, de Cabo R, Navas P.

Aging Cell. 2009 Apr;8(2):140-51. doi: 10.1111/j.1474-9726.2009.00461.x. Epub 2009 Feb 23.

10.

Sir2 blocks extreme life-span extension.

Fabrizio P, Gattazzo C, Battistella L, Wei M, Cheng C, McGrew K, Longo VD.

Cell. 2005 Nov 18;123(4):655-67.

11.

Deteriorated stress response in stationary-phase yeast: Sir2 and Yap1 are essential for Hsf1 activation by heat shock and oxidative stress, respectively.

Nussbaum I, Weindling E, Jubran R, Cohen A, Bar-Nun S.

PLoS One. 2014 Oct 30;9(10):e111505. doi: 10.1371/journal.pone.0111505. eCollection 2014.

12.
13.

Proteasomes, Sir2, and Hxk2 form an interconnected aging network that impinges on the AMPK/Snf1-regulated transcriptional repressor Mig1.

Yao Y, Tsuchiyama S, Yang C, Bulteau AL, He C, Robison B, Tsuchiya M, Miller D, Briones V, Tar K, Potrero A, Friguet B, Kennedy BK, Schmidt M.

PLoS Genet. 2015 Jan 28;11(1):e1004968. doi: 10.1371/journal.pgen.1004968. eCollection 2015 Jan.

14.

Sir2 is induced by oxidative stress in a yeast model of Huntington disease and its activation reduces protein aggregation.

Sorolla MA, Nierga C, Rodríguez-Colman MJ, Reverter-Branchat G, Arenas A, Tamarit J, Ros J, Cabiscol E.

Arch Biochem Biophys. 2011 Jun 1;510(1):27-34. doi: 10.1016/j.abb.2011.04.002. Epub 2011 Apr 13.

PMID:
21513696
15.

A novel assay for replicative lifespan in Saccharomyces cerevisiae.

Jarolim S, Millen J, Heeren G, Laun P, Goldfarb DS, Breitenbach M.

FEMS Yeast Res. 2004 Nov;5(2):169-77.

16.

Nicotinamide supplementation phenocopies SIR2 inactivation by modulating carbon metabolism and respiration during yeast chronological aging.

Orlandi I, Coppola DP, Strippoli M, Ronzulli R, Vai M.

Mech Ageing Dev. 2016 Jun 16. pii: S0047-6374(16)30092-6. doi: 10.1016/j.mad.2016.06.006. [Epub ahead of print]

17.

SNCA (α-synuclein)-induced toxicity in yeast cells is dependent on sirtuin 2 (Sir2)-mediated mitophagy.

Sampaio-Marques B, Felgueiras C, Silva A, Rodrigues M, Tenreiro S, Franssens V, Reichert AS, Outeiro TF, Winderickx J, Ludovico P.

Autophagy. 2012 Oct;8(10):1494-509. doi: 10.4161/auto.21275. Epub 2012 Aug 23.

PMID:
22914317
18.
19.

Sir2 plays a key role in cell fate determination upon SAPK activation.

Vendrell A, Posas F.

Aging (Albany NY). 2011 Dec;3(12):1163-8.

20.
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