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Items: 1 to 20 of 81

1.

Genetic elevation of sphingosine 1-phosphate suppresses dystrophic muscle phenotypes in Drosophila.

Pantoja M, Fischer KA, Ieronimakis N, Reyes M, Ruohola-Baker H.

Development. 2013 Jan 1;140(1):136-46. doi: 10.1242/dev.087791. Epub 2012 Nov 15.

2.

Molecular mechanism of sphingosine-1-phosphate action in Duchenne muscular dystrophy.

Nguyen-Tran DH, Hait NC, Sperber H, Qi J, Fischer K, Ieronimakis N, Pantoja M, Hays A, Allegood J, Reyes M, Spiegel S, Ruohola-Baker H.

Dis Model Mech. 2014 Jan;7(1):41-54. doi: 10.1242/dmm.013631. Epub 2013 Sep 25.

3.

Sphingosine-1-phosphate lyase downregulation promotes colon carcinogenesis through STAT3-activated microRNAs.

Degagné E, Pandurangan A, Bandhuvula P, Kumar A, Eltanawy A, Zhang M, Yoshinaga Y, Nefedov M, de Jong PJ, Fong LG, Young SG, Bittman R, Ahmedi Y, Saba JD.

J Clin Invest. 2014 Dec;124(12):5368-84. doi: 10.1172/JCI74188. Epub 2014 Oct 27.

4.

The spinster homolog, two of hearts, is required for sphingosine 1-phosphate signaling in zebrafish.

Osborne N, Brand-Arzamendi K, Ober EA, Jin SW, Verkade H, Holtzman NG, Yelon D, Stainier DY.

Curr Biol. 2008 Dec 9;18(23):1882-8. doi: 10.1016/j.cub.2008.10.061.

5.

The role of sphingosine-1-phosphate transporter Spns2 in immune system function.

Nijnik A, Clare S, Hale C, Chen J, Raisen C, Mottram L, Lucas M, Estabel J, Ryder E, Adissu H; Sanger Mouse Genetics Project, Adams NC, Ramirez-Solis R, White JK, Steel KP, Dougan G, Hancock RE.

J Immunol. 2012 Jul 1;189(1):102-11. doi: 10.4049/jimmunol.1200282. Epub 2012 Jun 4.

6.
7.

De novo biosynthesis of dihydrosphingosine-1-phosphate by sphingosine kinase 1 in mammalian cells.

Berdyshev EV, Gorshkova IA, Usatyuk P, Zhao Y, Saatian B, Hubbard W, Natarajan V.

Cell Signal. 2006 Oct;18(10):1779-92. Epub 2006 Mar 10.

PMID:
16529909
8.

Role of human sphingosine-1-phosphate phosphatase 1 in the regulation of intra- and extracellular sphingosine-1-phosphate levels and cell viability.

Johnson KR, Johnson KY, Becker KP, Bielawski J, Mao C, Obeid LM.

J Biol Chem. 2003 Sep 5;278(36):34541-7. Epub 2003 Jun 18.

9.

Sphingosine 1-phosphate induces MKP-1 expression via p38 MAPK- and CREB-mediated pathways in airway smooth muscle cells.

Che W, Manetsch M, Quante T, Rahman MM, Patel BS, Ge Q, Ammit AJ.

Biochim Biophys Acta. 2012 Oct;1823(10):1658-65. doi: 10.1016/j.bbamcr.2012.06.011. Epub 2012 Jun 25.

10.

Role of sphingosine kinases and lipid phosphate phosphatases in regulating spatial sphingosine 1-phosphate signalling in health and disease.

Pyne S, Lee SC, Long J, Pyne NJ.

Cell Signal. 2009 Jan;21(1):14-21. doi: 10.1016/j.cellsig.2008.08.008. Epub 2008 Aug 15. Review.

PMID:
18768158
11.

The reduction of allograft arteriosclerosis in intestinal transplant is associated with sphingosine kinase 1/sphingosine-1-phosphate signaling after fish oil treatment.

Li Q, Wang C, Zhang Q, Tang C, Li N, Li J.

Transplantation. 2012 May 27;93(10):989-96. doi: 10.1097/TP.0b013e31824d709d.

PMID:
22466786
12.

An autocrine sphingosine-1-phosphate signaling loop enhances NF-kappaB-activation and survival.

Blom T, Bergelin N, Meinander A, Löf C, Slotte JP, Eriksson JE, Törnquist K.

BMC Cell Biol. 2010 Jun 24;11:45. doi: 10.1186/1471-2121-11-45.

13.

Sphingosine 1-phosphate signal transduction in muscle cells.

Meacci E, Donati C, Farnararo M, Bruni P.

Ital J Biochem. 2003 Mar;52(1):25-7. Review.

PMID:
12833634
14.

Regulation of autophagy and its associated cell death by "sphingolipid rheostat": reciprocal role of ceramide and sphingosine 1-phosphate in the mammalian target of rapamycin pathway.

Taniguchi M, Kitatani K, Kondo T, Hashimoto-Nishimura M, Asano S, Hayashi A, Mitsutake S, Igarashi Y, Umehara H, Takeya H, Kigawa J, Okazaki T.

J Biol Chem. 2012 Nov 16;287(47):39898-910. doi: 10.1074/jbc.M112.416552. Epub 2012 Oct 3.

15.

S1P lyase in skeletal muscle regeneration and satellite cell activation: exposing the hidden lyase.

Saba JD, de la Garza-Rodea AS.

Biochim Biophys Acta. 2013 Jan;1831(1):167-75. doi: 10.1016/j.bbalip.2012.06.009. Epub 2012 Jun 28. Review.

16.

Sphingosine-1-phosphate signaling in skeletal muscle cells.

Meacci E, Bini F, Battistini C.

Methods Mol Biol. 2012;874:155-65. doi: 10.1007/978-1-61779-800-9_12.

PMID:
22528446
17.

Generation and metabolism of bioactive sphingosine-1-phosphate.

Le Stunff H, Milstien S, Spiegel S.

J Cell Biochem. 2004 Aug 1;92(5):882-99. Review.

PMID:
15258913
18.

Drosophila as a starting point for developing therapeutics for the rare disease Duchenne Muscular Dystrophy.

Pantoja M, Ruohola-Baker H.

Rare Dis. 2013 May 10;1:e24995. doi: 10.4161/rdis.24995. eCollection 2013.

19.

Sphingosine-1-phosphate and lipid phosphohydrolases.

Le Stunff H, Peterson C, Liu H, Milstien S, Spiegel S.

Biochim Biophys Acta. 2002 May 23;1582(1-3):8-17. Review.

PMID:
12069805
20.

The sphingosine 1-phosphate (S1P) signaling pathway is regulated during pregnancy in sheep.

Dunlap KA, Kwak HI, Burghardt RC, Bazer FW, Magness RR, Johnson GA, Bayless KJ.

Biol Reprod. 2010 May;82(5):876-87. doi: 10.1095/biolreprod.109.081604. Epub 2010 Jan 27.

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