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Results: 1 to 20 of 99

1.

Structural insights into the specific anti-HIV property of actinohivin: structure of its complex with the α(1-2)mannobiose moiety of gp120.

Hoque MM, Suzuki K, Tsunoda M, Jiang J, Zhang F, Takahashi A, Ohbayashi N, Zhang X, Tanaka H, Omura S, Takénaka A.

Acta Crystallogr D Biol Crystallogr. 2012 Dec;68(Pt 12):1671-9. doi: 10.1107/S0907444912040498. Epub 2012 Nov 9.

PMID:
23151632
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The Characteristic Structure of Anti-HIV Actinohivin in Complex with Three HMTG D1 Chains of HIV-gp120.

Zhang F, Hoque MM, Jiang J, Suzuki K, Tsunoda M, Takeda Y, Ito Y, Kawai G, Tanaka H, Takénaka A.

Chembiochem. 2014 Dec 15;15(18):2766-73. doi: 10.1002/cbic.201402352. Epub 2014 Nov 17.

PMID:
25403811
[PubMed - in process]
3.

Mechanism by which the lectin actinohivin blocks HIV infection of target cells.

Tanaka H, Chiba H, Inokoshi J, Kuno A, Sugai T, Takahashi A, Ito Y, Tsunoda M, Suzuki K, Takénaka A, Sekiguchi T, Umeyama H, Hirabayashi J, Omura S.

Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15633-8. doi: 10.1073/pnas.0907572106. Epub 2009 Aug 26.

PMID:
19717426
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Actinohivin: specific amino acid residues essential for anti-HIV activity.

Takahashi A, Inokoshi J, Tsunoda M, Suzuki K, Takenaka A, Sekiguchi T, Omura S, Tanaka H.

J Antibiot (Tokyo). 2010 Nov;63(11):661-5. doi: 10.1038/ja.2010.106. Epub 2010 Sep 15.

PMID:
20842142
[PubMed - indexed for MEDLINE]
5.

Actinohivin, a novel anti-human immunodeficiency virus protein from an actinomycete, inhibits viral entry to cells by binding high-mannose type sugar chains of gp120.

Chiba H, Inokoshi J, Nakashima H, Omura S, Tanaka H.

Biochem Biophys Res Commun. 2004 Mar 26;316(1):203-10.

PMID:
15003531
[PubMed - indexed for MEDLINE]
6.

The high mannose-type glycan binding lectin actinohivin: dimerization greatly improves anti-HIV activity.

Takahashi A, Inokoshi J, Hachiya A, Oka S, Omura S, Tanaka H.

J Antibiot (Tokyo). 2011 Aug;64(8):551-7. doi: 10.1038/ja.2011.51. Epub 2011 Jun 22.

PMID:
21694730
[PubMed - indexed for MEDLINE]
7.

Peculiarity in crystal packing of anti-HIV lectin actinohivin in complex with α(1-2)mannobiose.

Suzuki K, Tsunoda M, Hoque MM, Zhang F, Jiang J, Zhang X, Ohbayashi N, Tanaka H, Takénaka A.

Acta Crystallogr D Biol Crystallogr. 2013 Sep;69(Pt 9):1818-25. doi: 10.1107/S0907444913017812. Epub 2013 Aug 17.

PMID:
23999305
[PubMed - indexed for MEDLINE]
8.

Crystallographic study of the interaction of the anti-HIV lectin actinohivin with the α(1-2)mannobiose moiety of gp120 HMTG.

Suzuki K, Ohbayashi N, Jiang J, Zhang X, Hoque MM, Tsunoda M, Murayama K, Tanaka H, Takénaka A.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Sep 1;68(Pt 9):1060-3. doi: 10.1107/S1744309112031077. Epub 2012 Aug 30.

PMID:
22949194
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Actinohivin, a broadly neutralizing prokaryotic lectin, inhibits HIV-1 infection by specifically targeting high-mannose-type glycans on the gp120 envelope.

Hoorelbeke B, Huskens D, Férir G, François KO, Takahashi A, Van Laethem K, Schols D, Tanaka H, Balzarini J.

Antimicrob Agents Chemother. 2010 Aug;54(8):3287-301. doi: 10.1128/AAC.00254-10. Epub 2010 May 24.

PMID:
20498311
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Essential regions for antiviral activities of actinohivin, a sugar-binding anti-human immunodeficiency virus protein from an actinomycete.

Takahashi A, Inokoshi J, Chiba H, Omura S, Tanaka H.

Arch Biochem Biophys. 2005 May 15;437(2):233-40. Epub 2005 Apr 5.

PMID:
15850563
[PubMed - indexed for MEDLINE]
11.
12.

Burkholderia oklahomensis agglutinin is a canonical two-domain OAA-family lectin: structures, carbohydrate binding and anti-HIV activity.

Whitley MJ, Furey W, Kollipara S, Gronenborn AM.

FEBS J. 2013 May;280(9):2056-67. doi: 10.1111/febs.12229. Epub 2013 Apr 2.

PMID:
23480609
[PubMed - indexed for MEDLINE]
Free PMC Article
13.
14.

Solution and crystal molecular dynamics simulation study of m4-cyanovirin-N mutants complexed with di-mannose.

Vorontsov II, Miyashita O.

Biophys J. 2009 Nov 4;97(9):2532-40. doi: 10.1016/j.bpj.2009.08.011.

PMID:
19883596
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Dissecting carbohydrate-Cyanovirin-N binding by structure-guided mutagenesis: functional implications for viral entry inhibition.

Barrientos LG, Matei E, Lasala F, Delgado R, Gronenborn AM.

Protein Eng Des Sel. 2006 Dec;19(12):525-35. Epub 2006 Sep 29.

PMID:
17012344
[PubMed - indexed for MEDLINE]
Free Article
18.

Solution structure of the monovalent lectin microvirin in complex with Man(alpha)(1-2)Man provides a basis for anti-HIV activity with low toxicity.

Shahzad-ul-Hussan S, Gustchina E, Ghirlando R, Clore GM, Bewley CA.

J Biol Chem. 2011 Jun 10;286(23):20788-96. doi: 10.1074/jbc.M111.232678. Epub 2011 Apr 6.

PMID:
21471192
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Insights into carbohydrate recognition by Narcissus pseudonarcissus lectin: the crystal structure at 2 A resolution in complex with alpha1-3 mannobiose.

Sauerborn MK, Wright LM, Reynolds CD, Grossmann JG, Rizkallah PJ.

J Mol Biol. 1999 Jul 2;290(1):185-99.

PMID:
10388566
[PubMed - indexed for MEDLINE]
20.

The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of alpha1-->2 mannose residues on the outer face of gp120.

Scanlan CN, Pantophlet R, Wormald MR, Ollmann Saphire E, Stanfield R, Wilson IA, Katinger H, Dwek RA, Rudd PM, Burton DR.

J Virol. 2002 Jul;76(14):7306-21.

PMID:
12072529
[PubMed - indexed for MEDLINE]
Free PMC Article

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