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Regulation of mesenchymal stem cell chondrogenesis by glucose through protein kinase C/transforming growth factor signaling.

Tsai TL, Manner PA, Li WJ.

Osteoarthritis Cartilage. 2013 Feb;21(2):368-76. doi: 10.1016/j.joca.2012.11.001. Epub 2012 Nov 11.


A chondromimetic microsphere for in situ spatially controlled chondrogenic differentiation of human mesenchymal stem cells.

Ansboro S, Hayes JS, Barron V, Browne S, Howard L, Greiser U, Lalor P, Shannon F, Barry FP, Pandit A, Murphy JM.

J Control Release. 2014 Apr 10;179:42-51. doi: 10.1016/j.jconrel.2014.01.023. Epub 2014 Jan 31.


Mechanical load modulates chondrogenesis of human mesenchymal stem cells through the TGF-beta pathway.

Li Z, Kupcsik L, Yao SJ, Alini M, Stoddart MJ.

J Cell Mol Med. 2010 Jun;14(6A):1338-46. doi: 10.1111/j.1582-4934.2009.00780.x. Epub 2009 May 11.


Spatiotemporal regulation of chondrogenic differentiation with controlled delivery of transforming growth factor-β1 from gelatin microspheres in mesenchymal stem cell aggregates.

Solorio LD, Dhami CD, Dang PN, Vieregge EL, Alsberg E.

Stem Cells Transl Med. 2012 Aug;1(8):632-9. doi: 10.5966/sctm.2012-0039. Epub 2012 Jul 27.


Temporal exposure to chondrogenic factors modulates human mesenchymal stem cell chondrogenesis in hydrogels.

Buxton AN, Bahney CS, Yoo JU, Johnstone B.

Tissue Eng Part A. 2011 Feb;17(3-4):371-80. doi: 10.1089/ten.TEA.2009.0839. Epub 2010 Oct 25.


Stem cell shape regulates a chondrogenic versus myogenic fate through Rac1 and N-cadherin.

Gao L, McBeath R, Chen CS.

Stem Cells. 2010 Mar 31;28(3):564-72. doi: 10.1002/stem.308.


Involvement of Gas7 along the ERK1/2 MAP kinase and SOX9 pathway in chondrogenesis of human marrow-derived mesenchymal stem cells.

Chang Y, Ueng SW, Lin-Chao S, Chao CC.

Osteoarthritis Cartilage. 2008 Nov;16(11):1403-12. doi: 10.1016/j.joca.2008.03.018. Epub 2008 May 1.


Is continuous treatment with transforming growth factor-beta necessary to induce chondrogenic differentiation in mesenchymal stem cells?

Kim HJ, Kim YJ, Im GI.

Cells Tissues Organs. 2009;190(1):1-10. doi: 10.1159/000153041. Epub 2008 Aug 29.


Transforming growth factor-beta-mediated chondrogenesis of human mesenchymal progenitor cells involves N-cadherin and mitogen-activated protein kinase and Wnt signaling cross-talk.

Tuli R, Tuli S, Nandi S, Huang X, Manner PA, Hozack WJ, Danielson KG, Hall DJ, Tuan RS.

J Biol Chem. 2003 Oct 17;278(42):41227-36. Epub 2003 Jul 31.


Chondrogenic differentiation of ATDC5 and hMSCs could be induced by a novel scaffold-tricalcium phosphate-collagen-hyaluronan without any exogenous growth factors in vitro.

Meng F, He A, Zhang Z, Zhang Z, Lin Z, Yang Z, Long Y, Wu G, Kang Y, Liao W.

J Biomed Mater Res A. 2014 Aug;102(8):2725-35. doi: 10.1002/jbm.a.34948. Epub 2013 Sep 24.


Effect of IGF-I in the chondrogenesis of bone marrow mesenchymal stem cells in the presence or absence of TGF-beta signaling.

Longobardi L, O'Rear L, Aakula S, Johnstone B, Shimer K, Chytil A, Horton WA, Moses HL, Spagnoli A.

J Bone Miner Res. 2006 Apr;21(4):626-36. Epub 2006 Apr 5.


Pharmacological modulation of human mesenchymal stem cell chondrogenesis by a chemically oversulfated polysaccharide of marine origin: potential application to cartilage regenerative medicine.

Merceron C, Portron S, Vignes-Colombeix C, Rederstorff E, Masson M, Lesoeur J, Sourice S, Sinquin C, Colliec-Jouault S, Weiss P, Vinatier C, Guicheux J.

Stem Cells. 2012 Mar;30(3):471-80. doi: 10.1002/stem.1686.


Trichostatin A inhibits TGF-β1 induced in vitro chondrogenesis of hMSCs through Sp1 suppression.

Wang JP, Wen MH, Chen YT, Lee HH, Chiang ER, Lee YT, Liu CL, Chen TH, Hung SC.

Differentiation. 2011 Feb;81(2):119-26. doi: 10.1016/j.diff.2010.10.003. Epub 2010 Nov 12.


The effects of cyclic hydrostatic pressure on chondrogenesis and viability of human adipose- and bone marrow-derived mesenchymal stem cells in three-dimensional agarose constructs.

Puetzer J, Williams J, Gillies A, Bernacki S, Loboa EG.

Tissue Eng Part A. 2013 Jan;19(1-2):299-306. doi: 10.1089/ten.TEA.2012.0015. Epub 2012 Sep 26.


p38 mitogen-activated protein kinase functionally contributes to chondrogenesis induced by growth/differentiation factor-5 in ATDC5 cells.

Nakamura K, Shirai T, Morishita S, Uchida S, Saeki-Miura K, Makishima F.

Exp Cell Res. 1999 Aug 1;250(2):351-63.


Interplay between local versus soluble transforming growth factor-beta and fibrin scaffolds: role of cells and impact on human mesenchymal stem cell chondrogenesis.

Diederichs S, Baral K, Tanner M, Richter W.

Tissue Eng Part A. 2012 Jun;18(11-12):1140-50. doi: 10.1089/ten.TEA.2011.0426. Epub 2012 May 14.


Inhibition of TAK1 and/or JAK can rescue impaired chondrogenic differentiation of human mesenchymal stem cells in osteoarthritis-like conditions.

van Beuningen HM, de Vries-van Melle ML, Vitters EL, Schreurs W, van den Berg WB, van Osch GJ, van der Kraan PM.

Tissue Eng Part A. 2014 Aug;20(15-16):2243-52. doi: 10.1089/ten.TEA.2013.0553. Epub 2014 Mar 25.


Stage-dependent effect of TGF-beta1 on chondrogenic differentiation of human embryonic stem cells.

Yang Z, Sui L, Toh WS, Lee EH, Cao T.

Stem Cells Dev. 2009 Jul-Aug;18(6):929-40. doi: 10.1089/scd.2008.0219.


Chondrogenesis of periodontal ligament stem cells by transforming growth factor-β3 and bone morphogenetic protein-6 in a normal healthy impacted third molar.

Choi S, Cho TJ, Kwon SK, Lee G, Cho J.

Int J Oral Sci. 2013 Mar;5(1):7-13. doi: 10.1038/ijos.2013.19. Epub 2013 Apr 12.

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