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Results: 1 to 20 of 147

1.

Attenuating endoplasmic reticulum stress as a novel therapeutic strategy in pulmonary hypertension.

Dromparis P, Paulin R, Stenson TH, Haromy A, Sutendra G, Michelakis ED.

Circulation. 2013 Jan 1;127(1):115-25. doi: 10.1161/CIRCULATIONAHA.112.133413. Epub 2012 Nov 13.

PMID:
23149668
[PubMed - indexed for MEDLINE]
Free Article
2.

Reduction of endoplasmic reticulum stress by 4-phenylbutyric acid prevents the development of hypoxia-induced pulmonary arterial hypertension.

Koyama M, Furuhashi M, Ishimura S, Mita T, Fuseya T, Okazaki Y, Yoshida H, Tsuchihashi K, Miura T.

Am J Physiol Heart Circ Physiol. 2014 May;306(9):H1314-23. doi: 10.1152/ajpheart.00869.2013. Epub 2014 Mar 7.

PMID:
24610918
[PubMed - indexed for MEDLINE]
3.

The role of Nogo and the mitochondria-endoplasmic reticulum unit in pulmonary hypertension.

Sutendra G, Dromparis P, Wright P, Bonnet S, Haromy A, Hao Z, McMurtry MS, Michalak M, Vance JE, Sessa WC, Michelakis ED.

Sci Transl Med. 2011 Jun 22;3(88):88ra55. doi: 10.1126/scitranslmed.3002194.

PMID:
21697531
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Uncoupling protein 2 deficiency mimics the effects of hypoxia and endoplasmic reticulum stress on mitochondria and triggers pseudohypoxic pulmonary vascular remodeling and pulmonary hypertension.

Dromparis P, Paulin R, Sutendra G, Qi AC, Bonnet S, Michelakis ED.

Circ Res. 2013 Jul 5;113(2):126-36. doi: 10.1161/CIRCRESAHA.112.300699. Epub 2013 May 7.

PMID:
23652801
[PubMed - indexed for MEDLINE]
Free Article
5.

Glucose-induced beta cell dysfunction in vivo in rats: link between oxidative stress and endoplasmic reticulum stress.

Tang C, Koulajian K, Schuiki I, Zhang L, Desai T, Ivovic A, Wang P, Robson-Doucette C, Wheeler MB, Minassian B, Volchuk A, Giacca A.

Diabetologia. 2012 May;55(5):1366-79. doi: 10.1007/s00125-012-2474-8. Epub 2012 Mar 1.

PMID:
22396011
[PubMed - indexed for MEDLINE]
6.

Nitrite potently inhibits hypoxic and inflammatory pulmonary arterial hypertension and smooth muscle proliferation via xanthine oxidoreductase-dependent nitric oxide generation.

Zuckerbraun BS, Shiva S, Ifedigbo E, Mathier MA, Mollen KP, Rao J, Bauer PM, Choi JJ, Curtis E, Choi AM, Gladwin MT.

Circulation. 2010 Jan 5;121(1):98-109. doi: 10.1161/CIRCULATIONAHA.109.891077. Epub 2009 Dec 21.

PMID:
20026772
[PubMed - indexed for MEDLINE]
Free Article
7.

Endoplasmic reticulum stress participates in aortic valve calcification in hypercholesterolemic animals.

Cai Z, Li F, Gong W, Liu W, Duan Q, Chen C, Ni L, Xia Y, Cianflone K, Dong N, Wang DW.

Arterioscler Thromb Vasc Biol. 2013 Oct;33(10):2345-54. doi: 10.1161/ATVBAHA.112.300226. Epub 2013 Aug 8.

PMID:
23928865
[PubMed - indexed for MEDLINE]
8.

Sodium 4-phenylbutyrate protects against liver ischemia reperfusion injury by inhibition of endoplasmic reticulum-stress mediated apoptosis.

Vilatoba M, Eckstein C, Bilbao G, Smyth CA, Jenkins S, Thompson JA, Eckhoff DE, Contreras JL.

Surgery. 2005 Aug;138(2):342-51.

PMID:
16153446
[PubMed - indexed for MEDLINE]
9.

4-Phenylbutyric acid reduces endoplasmic reticulum stress, trypsin activation, and acinar cell apoptosis while increasing secretion in rat pancreatic acini.

Malo A, Krüger B, Göke B, Kubisch CH.

Pancreas. 2013 Jan;42(1):92-101. doi: 10.1097/MPA.0b013e318259f6ca. Erratum in: Pancreas. 2013 Mar;42(2):388.

PMID:
22889983
[PubMed - indexed for MEDLINE]
10.

Aberrant endoplasmic reticulum stress in vascular smooth muscle increases vascular contractility and blood pressure in mice deficient of AMP-activated protein kinase-α2 in vivo.

Liang B, Wang S, Wang Q, Zhang W, Viollet B, Zhu Y, Zou MH.

Arterioscler Thromb Vasc Biol. 2013 Mar;33(3):595-604. doi: 10.1161/ATVBAHA.112.300606. Epub 2013 Jan 3.

PMID:
23288166
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Dehydroepiandrosterone inhibits the Src/STAT3 constitutive activation in pulmonary arterial hypertension.

Paulin R, Meloche J, Jacob MH, Bisserier M, Courboulin A, Bonnet S.

Am J Physiol Heart Circ Physiol. 2011 Nov;301(5):H1798-809. doi: 10.1152/ajpheart.00654.2011. Epub 2011 Sep 2.

PMID:
21890685
[PubMed - indexed for MEDLINE]
Free Article
12.

YC-1 attenuates hypoxia-induced pulmonary arterial hypertension in mice.

Huh JW, Kim SY, Lee JH, Lee YS.

Pulm Pharmacol Ther. 2011 Dec;24(6):638-46. doi: 10.1016/j.pupt.2011.09.003. Epub 2011 Sep 24.

PMID:
21963997
[PubMed - indexed for MEDLINE]
13.

Effect of tauroursodeoxycholic acid on endoplasmic reticulum stress-induced caspase-12 activation.

Xie Q, Khaoustov VI, Chung CC, Sohn J, Krishnan B, Lewis DE, Yoffe B.

Hepatology. 2002 Sep;36(3):592-601.

PMID:
12198651
[PubMed - indexed for MEDLINE]
14.

Sodium 4-phenylbutyrate protects against cerebral ischemic injury.

Qi X, Hosoi T, Okuma Y, Kaneko M, Nomura Y.

Mol Pharmacol. 2004 Oct;66(4):899-908. Epub 2004 Jun 29.

PMID:
15226415
[PubMed - indexed for MEDLINE]
Free Article
15.

Cross-talk between the unfolded protein response and nuclear factor-κB signalling pathways regulates cytokine-mediated beta cell death in MIN6 cells and isolated mouse islets.

Chan JY, Biden TJ, Laybutt DR.

Diabetologia. 2012 Nov;55(11):2999-3009. doi: 10.1007/s00125-012-2657-3. Epub 2012 Jul 28.

PMID:
22893028
[PubMed - indexed for MEDLINE]
16.

Rescue treatment with a Rho-kinase inhibitor normalizes right ventricular function and reverses remodeling in juvenile rats with chronic pulmonary hypertension.

Xu EZ, Kantores C, Ivanovska J, Engelberts D, Kavanagh BP, McNamara PJ, Jankov RP.

Am J Physiol Heart Circ Physiol. 2010 Dec;299(6):H1854-64. doi: 10.1152/ajpheart.00595.2010. Epub 2010 Oct 1.

PMID:
20889845
[PubMed - indexed for MEDLINE]
Free Article
17.

Suppressive effects of 4-phenylbutyrate on the aggregation of Pael receptors and endoplasmic reticulum stress.

Kubota K, Niinuma Y, Kaneko M, Okuma Y, Sugai M, Omura T, Uesugi M, Uehara T, Hosoi T, Nomura Y.

J Neurochem. 2006 Jun;97(5):1259-68. Epub 2006 Mar 15.

PMID:
16539653
[PubMed - indexed for MEDLINE]
18.

Tauroursodeoxycholic acid reduces endoplasmic reticulum stress, trypsin activation, and acinar cell apoptosis while increasing secretion in rat pancreatic acini.

Malo A, Krüger B, Seyhun E, Schäfer C, Hoffmann RT, Göke B, Kubisch CH.

Am J Physiol Gastrointest Liver Physiol. 2010 Oct;299(4):G877-86. doi: 10.1152/ajpgi.00423.2009. Epub 2010 Jul 29.

PMID:
20671193
[PubMed - indexed for MEDLINE]
Free Article
19.

Dichloroacetate prevents and reverses pulmonary hypertension by inducing pulmonary artery smooth muscle cell apoptosis.

McMurtry MS, Bonnet S, Wu X, Dyck JR, Haromy A, Hashimoto K, Michelakis ED.

Circ Res. 2004 Oct 15;95(8):830-40. Epub 2004 Sep 16.

PMID:
15375007
[PubMed - indexed for MEDLINE]
Free Article
20.

Attenuation of endoplasmic reticulum stress using the chemical chaperone 4-phenylbutyric acid prevents cardiac fibrosis induced by isoproterenol.

Ayala P, Montenegro J, Vivar R, Letelier A, Urroz PA, Copaja M, Pivet D, Humeres C, Troncoso R, Vicencio JM, Lavandero S, Díaz-Araya G.

Exp Mol Pathol. 2012 Feb;92(1):97-104. doi: 10.1016/j.yexmp.2011.10.012. Epub 2011 Nov 10.

PMID:
22101259
[PubMed - indexed for MEDLINE]

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