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TLR4 as receptor for HMGB1 induced muscle dysfunction in myositis.

Zong M, Bruton JD, Grundtman C, Yang H, Li JH, Alexanderson H, Palmblad K, Andersson U, Harris HE, Lundberg IE, Westerblad H.

Ann Rheum Dis. 2013 Aug;72(8):1390-9. doi: 10.1136/annrheumdis-2012-202207. Epub 2012 Nov 12.


Effects of HMGB1 on in vitro responses of isolated muscle fibers and functional aspects in skeletal muscles of idiopathic inflammatory myopathies.

Grundtman C, Bruton J, Yamada T, Ostberg T, Pisetsky DS, Harris HE, Andersson U, Lundberg IE, Westerblad H.

FASEB J. 2010 Feb;24(2):570-8. doi: 10.1096/fj.09-144782. Epub 2009 Oct 16.


HMGB1 and TLR4 mediate skeletal muscle recovery in a murine model of hindlimb ischemia.

Sachdev U, Cui X, Tzeng E.

J Vasc Surg. 2013 Aug;58(2):460-9. doi: 10.1016/j.jvs.2012.11.071. Epub 2013 Feb 12.


High-mobility group box-1 impairs memory in mice through both toll-like receptor 4 and Receptor for Advanced Glycation End Products.

Mazarati A, Maroso M, Iori V, Vezzani A, Carli M.

Exp Neurol. 2011 Dec;232(2):143-8. doi: 10.1016/j.expneurol.2011.08.012. Epub 2011 Aug 22.


High mobility group box 1 promotes small intestinal damage induced by nonsteroidal anti-inflammatory drugs through Toll-like receptor 4.

Nadatani Y, Watanabe T, Tanigawa T, Machida H, Okazaki H, Yamagami H, Watanabe K, Tominaga K, Fujiwara Y, Arakawa T.

Am J Pathol. 2012 Jul;181(1):98-110. doi: 10.1016/j.ajpath.2012.03.039. Epub 2012 May 22.


High-mobility group box 1 inhibits gastric ulcer healing through Toll-like receptor 4 and receptor for advanced glycation end products.

Nadatani Y, Watanabe T, Tanigawa T, Ohkawa F, Takeda S, Higashimori A, Sogawa M, Yamagami H, Shiba M, Watanabe K, Tominaga K, Fujiwara Y, Takeuchi K, Arakawa T.

PLoS One. 2013 Nov 11;8(11):e80130. doi: 10.1371/journal.pone.0080130. eCollection 2013.


Reactive oxygen species and fatigue-induced prolonged low-frequency force depression in skeletal muscle fibres of rats, mice and SOD2 overexpressing mice.

Bruton JD, Place N, Yamada T, Silva JP, Andrade FH, Dahlstedt AJ, Zhang SJ, Katz A, Larsson NG, Westerblad H.

J Physiol. 2008 Jan 1;586(1):175-84. Epub 2007 Nov 15.


Receptor for advanced glycation end products and its ligand high-mobility group box-1 mediate allergic airway sensitization and airway inflammation.

Ullah MA, Loh Z, Gan WJ, Zhang V, Yang H, Li JH, Yamamoto Y, Schmidt AM, Armour CL, Hughes JM, Phipps S, Sukkar MB.

J Allergy Clin Immunol. 2014 Aug;134(2):440-50. doi: 10.1016/j.jaci.2013.12.1035. Epub 2014 Feb 4.


Receptor for Advanced Glycation Endproducts is upregulated in temporal lobe epilepsy and contributes to experimental seizures.

Iori V, Maroso M, Rizzi M, Iyer AM, Vertemara R, Carli M, Agresti A, Antonelli A, Bianchi ME, Aronica E, Ravizza T, Vezzani A.

Neurobiol Dis. 2013 Oct;58:102-14. doi: 10.1016/j.nbd.2013.03.006. Epub 2013 Mar 21.


High-mobility group box 1 promotes metalloproteinase-9 upregulation through Toll-like receptor 4 after cerebral ischemia.

Qiu J, Xu J, Zheng Y, Wei Y, Zhu X, Lo EH, Moskowitz MA, Sims JR.

Stroke. 2010 Sep;41(9):2077-82. doi: 10.1161/STROKEAHA.110.590463. Epub 2010 Jul 29.


High-mobility group box 1 inhibits HCO(3)(-) absorption in medullary thick ascending limb through a basolateral receptor for advanced glycation end products pathway.

Good DW, George T, Watts BA 3rd.

Am J Physiol Renal Physiol. 2015 Oct 15;309(8):F720-30. doi: 10.1152/ajprenal.00227.2015. Epub 2015 Jul 15.


HMGB1 signals through toll-like receptor (TLR) 4 and TLR2.

Yu M, Wang H, Ding A, Golenbock DT, Latz E, Czura CJ, Fenton MJ, Tracey KJ, Yang H.

Shock. 2006 Aug;26(2):174-9.


High-mobility group box-1 in ischemia-reperfusion injury of the heart.

Andrassy M, Volz HC, Igwe JC, Funke B, Eichberger SN, Kaya Z, Buss S, Autschbach F, Pleger ST, Lukic IK, Bea F, Hardt SE, Humpert PM, Bianchi ME, Mairbäurl H, Nawroth PP, Remppis A, Katus HA, Bierhaus A.

Circulation. 2008 Jun 24;117(25):3216-26. doi: 10.1161/CIRCULATIONAHA.108.769331.


KATP channel deficiency in mouse flexor digitorum brevis causes fibre damage and impairs Ca2+ release and force development during fatigue in vitro.

Cifelli C, Bourassa F, Gariépy L, Banas K, Benkhalti M, Renaud JM.

J Physiol. 2007 Jul 15;582(Pt 2):843-57. Epub 2007 May 17.


The effects of the myosin-II inhibitor N-benzyl-p-toluene sulphonamide on fatigue in mouse single intact toe muscle fibres.

Bruton J, Pinniger GJ, Lännergren J, Westerblad H.

Acta Physiol (Oxf). 2006 Jan;186(1):59-66.


HMGB1 enhances the proinflammatory activity of lipopolysaccharide by promoting the phosphorylation of MAPK p38 through receptor for advanced glycation end products.

Qin YH, Dai SM, Tang GS, Zhang J, Ren D, Wang ZW, Shen Q.

J Immunol. 2009 Nov 15;183(10):6244-50. doi: 10.4049/jimmunol.0900390.


[Effect of high mobility group box 1 (HMGB1) in cultured human periodontal ligament cells].

Hasegawa N.

Kokubyo Gakkai Zasshi. 2008 Oct;75(3):155-61. Japanese.


Extracellular high mobility group box-1 inhibits R5 and X4 HIV-1 strains replication in mononuclear phagocytes without induction of chemokines and cytokines.

Cassetta L, Fortunato O, Adduce L, Rizzi C, Hering J, Rovere-Querini P, Bianchi ME, Alfano M, Poli G.

AIDS. 2009 Mar 13;23(5):567-77. doi: 10.1097/QAD.0b013e328325a47e.


High mobility group box 1 protein interacts with multiple Toll-like receptors.

Park JS, Gamboni-Robertson F, He Q, Svetkauskaite D, Kim JY, Strassheim D, Sohn JW, Yamada S, Maruyama I, Banerjee A, Ishizaka A, Abraham E.

Am J Physiol Cell Physiol. 2006 Mar;290(3):C917-24. Epub 2005 Nov 2.

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