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Items: 1 to 20 of 96

1.

The TSC1/2 complex controls Drosophila pigmentation through TORC1-dependent regulation of catecholamine biosynthesis.

Zitserman D, Gupta S, Kruger WD, Karbowniczek M, Roegiers F.

PLoS One. 2012;7(11):e48720. doi: 10.1371/journal.pone.0048720. Epub 2012 Nov 7.

2.

TSC1/TSC2 and Rheb have different effects on TORC1 and TORC2 activity.

Yang Q, Inoki K, Kim E, Guan KL.

Proc Natl Acad Sci U S A. 2006 May 2;103(18):6811-6. Epub 2006 Apr 20.

3.

The evolutionarily conserved TSC/Rheb pathway activates Notch in tuberous sclerosis complex and Drosophila external sensory organ development.

Karbowniczek M, Zitserman D, Khabibullin D, Hartman T, Yu J, Morrison T, Nicolas E, Squillace R, Roegiers F, Henske EP.

J Clin Invest. 2010 Jan;120(1):93-102. doi: 10.1172/JCI40221. Epub 2009 Dec 28.

4.

TSC1/2 regulates intestinal stem cell maintenance and lineage differentiation through Rheb-TORC1-S6K but independently of nutritional status or Notch regulation.

Quan Z, Sun P, Lin G, Xi R.

J Cell Sci. 2013 Sep 1;126(Pt 17):3884-92. doi: 10.1242/jcs.125294. Epub 2013 Jul 10.

5.

Rheb activation of mTOR and S6K1 signaling.

Hanrahan J, Blenis J.

Methods Enzymol. 2006;407:542-55.

PMID:
16757352
6.

Rheb is an essential regulator of S6K in controlling cell growth in Drosophila.

Stocker H, Radimerski T, Schindelholz B, Wittwer F, Belawat P, Daram P, Breuer S, Thomas G, Hafen E.

Nat Cell Biol. 2003 Jun;5(6):559-65.

PMID:
12766775
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9.

Amino acid regulation of TOR complex 1.

Avruch J, Long X, Ortiz-Vega S, Rapley J, Papageorgiou A, Dai N.

Am J Physiol Endocrinol Metab. 2009 Apr;296(4):E592-602. doi: 10.1152/ajpendo.90645.2008. Epub 2008 Sep 2. Review.

10.

Tuberous sclerosis complex regulates Drosophila neuromuscular junction growth via the TORC2/Akt pathway.

Natarajan R, Trivedi-Vyas D, Wairkar YP.

Hum Mol Genet. 2013 May 15;22(10):2010-23. doi: 10.1093/hmg/ddt053. Epub 2013 Feb 7.

11.

TSC1/2 tumour suppressor complex maintains Drosophila germline stem cells by preventing differentiation.

Sun P, Quan Z, Zhang B, Wu T, Xi R.

Development. 2010 Aug 1;137(15):2461-9. doi: 10.1242/dev.051466. Epub 2010 Jun 23.

12.

Drosophila TCTP is essential for growth and proliferation through regulation of dRheb GTPase.

Hsu YC, Chern JJ, Cai Y, Liu M, Choi KW.

Nature. 2007 Feb 15;445(7129):785-8.

PMID:
17301792
13.

Insulin and amino-acid regulation of mTOR signaling and kinase activity through the Rheb GTPase.

Avruch J, Hara K, Lin Y, Liu M, Long X, Ortiz-Vega S, Yonezawa K.

Oncogene. 2006 Oct 16;25(48):6361-72. Review.

PMID:
17041622
14.

Temporal and spatial expression of the yellow gene in correlation with cuticle formation and dopa decarboxylase activity in Drosophila development.

Walter MF, Black BC, Afshar G, Kermabon AY, Wright TR, Biessmann H.

Dev Biol. 1991 Sep;147(1):32-45.

PMID:
1879614
15.

The mTOR/S6K signalling pathway: the role of the TSC1/2 tumour suppressor complex and the proto-oncogene Rheb.

Nobukini T, Thomas G.

Novartis Found Symp. 2004;262:148-54; discussion 154-9, 265-8. Review.

PMID:
15562827
16.

Molecular mechanisms through which amino acids mediate signaling through the mammalian target of rapamycin.

Kimball SR, Jefferson LS.

Curr Opin Clin Nutr Metab Care. 2004 Jan;7(1):39-44. Review.

PMID:
15090902
17.

Ribosomal protein S6 kinase is a critical downstream effector of the target of rapamycin complex 1 for long-term facilitation in Aplysia.

Weatherill DB, Dyer J, Sossin WS.

J Biol Chem. 2010 Apr 16;285(16):12255-67. doi: 10.1074/jbc.M109.071142. Epub 2010 Feb 22.

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Rhebbing up mTOR: new insights on TSC1 and TSC2, and the pathogenesis of tuberous sclerosis.

Kwiatkowski DJ.

Cancer Biol Ther. 2003 Sep-Oct;2(5):471-6. Review.

PMID:
14614311
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