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Items: 1 to 20 of 129

1.

The lupus-prone NZM2410/NZW strain-derived Sle1b sublocus alters the germinal center checkpoint in female mice in a B cell-intrinsic manner.

Wong EB, Khan TN, Mohan C, Rahman ZS.

J Immunol. 2012 Dec 15;189(12):5667-81. doi: 10.4049/jimmunol.1201661. Epub 2012 Nov 9.

2.

The lupus susceptibility locus Sle1 breaches peripheral B cell tolerance at the antibody-forming cell and germinal center checkpoints.

Vuyyuru R, Mohan C, Manser T, Rahman ZS.

J Immunol. 2009 Nov 1;183(9):5716-27. doi: 10.4049/jimmunol.0804215. Epub 2009 Oct 14.

3.

Several genes contribute to the production of autoreactive B and T cells in the murine lupus susceptibility locus Sle1c.

Chen Y, Perry D, Boackle SA, Sobel ES, Molina H, Croker BP, Morel L.

J Immunol. 2005 Jul 15;175(2):1080-9.

4.

B cell-intrinsic CD84 and Ly108 maintain germinal center B cell tolerance.

Wong EB, Soni C, Chan AY, Domeier PP, Shwetank, Abraham T, Limaye N, Khan TN, Elias MJ, Chodisetti SB, Wakeland EK, Rahman ZS.

J Immunol. 2015 May 1;194(9):4130-43. doi: 10.4049/jimmunol.1403023. Epub 2015 Mar 23.

5.

B cell-intrinsic TLR7 signaling is essential for the development of spontaneous germinal centers.

Soni C, Wong EB, Domeier PP, Khan TN, Satoh T, Akira S, Rahman ZS.

J Immunol. 2014 Nov 1;193(9):4400-14. doi: 10.4049/jimmunol.1401720. Epub 2014 Sep 24.

6.

Expression of the autoimmune Fcgr2b NZW allele fails to be upregulated in germinal center B cells and is associated with increased IgG production.

Rahman ZS, Niu H, Perry D, Wakeland E, Manser T, Morel L.

Genes Immun. 2007 Oct;8(7):604-12. Epub 2007 Aug 23.

PMID:
17713556
7.

Antigen-specific responses and ANA production in B6.Sle1b mice: a role for SAP.

Jennings P, Chan A, Schwartzberg P, Wakeland EK, Yuan D.

J Autoimmun. 2008 Dec;31(4):345-53. doi: 10.1016/j.jaut.2008.08.002. Epub 2008 Oct 8.

8.

Genetic dissection of SLE pathogenesis: adoptive transfer of Sle1 mediates the loss of tolerance by bone marrow-derived B cells.

Sobel ES, Mohan C, Morel L, Schiffenbauer J, Wakeland EK.

J Immunol. 1999 Feb 15;162(4):2415-21.

9.

The major murine systemic lupus erythematosus susceptibility locus Sle1 results in abnormal functions of both B and T cells.

Sobel ES, Satoh M, Chen Y, Wakeland EK, Morel L.

J Immunol. 2002 Sep 1;169(5):2694-700.

10.

Genetic dissection of systemic lupus erythematosus pathogenesis: evidence for functional expression of Sle3/5 by non-T cells.

Sobel ES, Morel L, Baert R, Mohan C, Schiffenbauer J, Wakeland EK.

J Immunol. 2002 Oct 1;169(7):4025-32.

11.

The Yaa locus and IFN-α fine-tune germinal center B cell selection in murine systemic lupus erythematosus.

Moisini I, Huang W, Bethunaickan R, Sahu R, Ricketts PG, Akerman M, Marion T, Lesser M, Davidson A.

J Immunol. 2012 Nov 1;189(9):4305-12. doi: 10.4049/jimmunol.1200745. Epub 2012 Sep 28.

12.

Distinct and synergistic roles of FcγRIIB deficiency and 129 strain-derived SLAM family proteins in the development of spontaneous germinal centers and autoimmunity.

Soni C, Domeier PP, Wong EB, Shwetank, Khan TN, Elias MJ, Schell SL, Lukacher AE, Cooper TK, Rahman ZS.

J Autoimmun. 2015 Sep;63:31-46. doi: 10.1016/j.jaut.2015.06.011. Epub 2015 Jul 7.

PMID:
26162758
15.

Mechanisms of peritoneal B-1a cells accumulation induced by murine lupus susceptibility locus Sle2.

Xu Z, Butfiloski EJ, Sobel ES, Morel L.

J Immunol. 2004 Nov 15;173(10):6050-8.

16.

An Ig mu-heavy chain transgene inhibits systemic lupus erythematosus immunopathology in autoimmune (NZB x NZW)F1 mice.

Wellmann U, Letz M, Schneider A, Amann K, Winkler TH.

Int Immunol. 2001 Dec;13(12):1461-9.

17.

Prolonged apoptotic cell accumulation in germinal centers of Mer-deficient mice causes elevated B cell and CD4+ Th cell responses leading to autoantibody production.

Khan TN, Wong EB, Soni C, Rahman ZS.

J Immunol. 2013 Feb 15;190(4):1433-46. doi: 10.4049/jimmunol.1200824. Epub 2013 Jan 14.

18.

A New Zealand Black-derived locus suppresses chronic graft-versus-host disease and autoantibody production through nonlymphoid bone marrow-derived cells.

Xu Z, Vallurupalli A, Fuhrman C, Ostrov D, Morel L.

J Immunol. 2011 Apr 1;186(7):4130-9. doi: 10.4049/jimmunol.1003512. Epub 2011 Feb 18.

20.

Activation of rheumatoid factor-specific B cells is antigen dependent and occurs preferentially outside of germinal centers in the lupus-prone NZM2410 mouse model.

Sang A, Niu H, Cullen J, Choi SC, Zheng YY, Wang H, Shlomchik MJ, Morel L.

J Immunol. 2014 Aug 15;193(4):1609-21. doi: 10.4049/jimmunol.1303000. Epub 2014 Jul 11.

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