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Items: 1 to 20 of 145

1.

Platelet-derived growth factor (PDGF)-C neutralization reveals differential roles of PDGF receptors in liver and kidney fibrosis.

Martin IV, Borkham-Kamphorst E, Zok S, van Roeyen CR, Eriksson U, Boor P, Hittatiya K, Fischer HP, Wasmuth HE, Weiskirchen R, Eitner F, Floege J, Ostendorf T.

Am J Pathol. 2013 Jan;182(1):107-17. doi: 10.1016/j.ajpath.2012.09.006. Epub 2012 Nov 7.

PMID:
23141925
2.

Platelet-derived growth factor isoform expression in carbon tetrachloride-induced chronic liver injury.

Borkham-Kamphorst E, Kovalenko E, van Roeyen CR, Gassler N, Bomble M, Ostendorf T, Floege J, Gressner AM, Weiskirchen R.

Lab Invest. 2008 Oct;88(10):1090-100. doi: 10.1038/labinvest.2008.71. Epub 2008 Jul 28.

4.

Platelet-derived growth factor-D modulates extracellular matrix homeostasis and remodeling through TIMP-1 induction and attenuation of MMP-2 and MMP-9 gelatinase activities.

Borkham-Kamphorst E, Alexi P, Tihaa L, Haas U, Weiskirchen R.

Biochem Biophys Res Commun. 2015 Feb 13;457(3):307-13. doi: 10.1016/j.bbrc.2014.12.106. Epub 2015 Jan 7.

PMID:
25576870
5.

The role of platelet-derived growth factor signaling in healing myocardial infarcts.

Zymek P, Bujak M, Chatila K, Cieslak A, Thakker G, Entman ML, Frangogiannis NG.

J Am Coll Cardiol. 2006 Dec 5;48(11):2315-23. Epub 2006 Nov 13.

6.

Crosstalk between PDGF and IGF-I receptors in rat liver myofibroblasts: implication for liver fibrogenesis.

Novosyadlyy R, Dudas J, Pannem R, Ramadori G, Scharf JG.

Lab Invest. 2006 Jul;86(7):710-23. Epub 2006 May 8.

7.

Pro-fibrogenic potential of PDGF-D in liver fibrosis.

Borkham-Kamphorst E, van Roeyen CR, Ostendorf T, Floege J, Gressner AM, Weiskirchen R.

J Hepatol. 2007 Jun;46(6):1064-74. Epub 2007 Feb 23.

PMID:
17397961
8.

Expression patterns of PDGF-A, -B, -C and -D and the PDGF-receptors alpha and beta in activated rat hepatic stellate cells (HSC).

Breitkopf K, Roeyen Cv, Sawitza I, Wickert L, Floege J, Gressner AM.

Cytokine. 2005 Sep 7;31(5):349-57.

PMID:
16039137
9.

The myofibroblastic conversion of peribiliary fibrogenic cells distinct from hepatic stellate cells is stimulated by platelet-derived growth factor during liver fibrogenesis.

Kinnman N, Francoz C, Barbu V, Wendum D, Rey C, Hultcrantz R, Poupon R, Housset C.

Lab Invest. 2003 Feb;83(2):163-73.

PMID:
12594232
10.

PDGF-D signaling in portal myofibroblasts and hepatic stellate cells proves identical to PDGF-B via both PDGF receptor type α and β.

Borkham-Kamphorst E, Meurer SK, Van de Leur E, Haas U, Tihaa L, Weiskirchen R.

Cell Signal. 2015 Jul;27(7):1305-14. doi: 10.1016/j.cellsig.2015.03.012. Epub 2015 Mar 27.

PMID:
25819339
11.

PDGF-C is a proinflammatory cytokine that mediates renal interstitial fibrosis.

Eitner F, Bücher E, van Roeyen C, Kunter U, Rong S, Seikrit C, Villa L, Boor P, Fredriksson L, Bäckström G, Eriksson U, Ostman A, Floege J, Ostendorf T.

J Am Soc Nephrol. 2008 Feb;19(2):281-9. doi: 10.1681/ASN.2007030290. Epub 2008 Jan 9. No abstract available.

12.

Inhibition of platelet-derived growth factor-mediated signal transduction and tumor growth by N-[4-(trifluoromethyl)-phenyl]5-methylisoxazole-4-carboxamide.

Shawver LK, Schwartz DP, Mann E, Chen H, Tsai J, Chu L, Taylorson L, Longhi M, Meredith S, Germain L, Jacobs JS, Tang C, Ullrich A, Berens ME, Hersh E, McMahon G, Hirth KP, Powell TJ.

Clin Cancer Res. 1997 Jul;3(7):1167-77.

13.

Acyclic retinoid targets platelet-derived growth factor signaling in the prevention of hepatic fibrosis and hepatocellular carcinoma development.

Okada H, Honda M, Campbell JS, Sakai Y, Yamashita T, Takebuchi Y, Hada K, Shirasaki T, Takabatake R, Nakamura M, Sunagozaka H, Tanaka T, Fausto N, Kaneko S.

Cancer Res. 2012 Sep 1;72(17):4459-71. doi: 10.1158/0008-5472.CAN-12-0028. Epub 2012 May 31.

14.

[Expression and significance of platelet derived growth factor and its receptor in liver tissues of patients with liver fibrosis].

Yuan N, Wang P, Wang X, Wang Z.

Zhonghua Gan Zang Bing Za Zhi. 2002 Feb;10(1):58-60. Chinese.

PMID:
11856507
15.

Platelet-derived growth factor (PDGF) and PDGF receptors in rat corpus cavernosum: changes in expression after transient in vivo hypoxia.

Aversa A, Basciani S, Visca P, Arizzi M, Gnessi L, Frajese G, Fabbri A.

J Endocrinol. 2001 Aug;170(2):395-402.

16.

[Effects of acupuncture intervention on hepatic platelet-derived growth factor signaling pathway in CCl4-induced hepatic fibrosis rats].

Kong DS, Ma J, Lu Y, Ni GX, Ni CY, Zhang XJ, Wang AY, Chen WX, Zheng SZ.

Zhen Ci Yan Jiu. 2012 Apr;37(2):87-92. Chinese.

PMID:
22764591
17.

Role of platelet-derived growth factor-CC in capillary rarefaction in renal fibrosis.

Boor P, Bábíčková J, Steegh F, Hautvast P, Martin IV, Djudjaj S, Nakagawa T, Ehling J, Gremse F, Bücher E, Eriksson U, van Roeyen CR, Eitner F, Lammers T, Floege J, Peutz-Kootstra CJ, Ostendorf T.

Am J Pathol. 2015 Aug;185(8):2132-42. doi: 10.1016/j.ajpath.2015.04.022.

PMID:
26216283
18.

Expression of platelet-derived growth factor (PDGF) in the epididymis and analysis of the epididymal development in PDGF-A, PDGF-B, and PDGF receptor beta deficient mice.

Basciani S, Mariani S, Arizzi M, Brama M, Ricci A, Betsholtz C, Bondjers C, Ricci G, Catizone A, Galdieri M, Spera G, Gnessi L.

Biol Reprod. 2004 Jan;70(1):168-77. Epub 2003 Oct 1.

19.

Platelet-derived growth factor receptor signaling activates pericyte-myofibroblast transition in obstructive and post-ischemic kidney fibrosis.

Chen YT, Chang FC, Wu CF, Chou YH, Hsu HL, Chiang WC, Shen J, Chen YM, Wu KD, Tsai TJ, Duffield JS, Lin SL.

Kidney Int. 2011 Dec;80(11):1170-81. doi: 10.1038/ki.2011.208. Epub 2011 Jun 29.

20.
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