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Items: 1 to 20 of 133

1.

Nicotinic α4β2 receptor imaging agents. Part IV. Synthesis and biological evaluation of 3-(2-(S)-3,4-dehydropyrrolinyl methoxy)-5-(3'-¹⁸F-fluoropropyl)pyridine (¹⁸F-Nifrolene) using PET.

Pichika R, Kuruvilla SA, Patel N, Vu K, Sinha S, Easwaramoorthy B, Narayanan TK, Shi B, Christian B, Mukherjee J.

Nucl Med Biol. 2013 Jan;40(1):117-25. doi: 10.1016/j.nucmedbio.2012.09.009. Epub 2012 Nov 7.

2.

Synthesis and evaluation of nicotine alpha4beta2 receptor radioligand, 5-(3'-18F-fluoropropyl)-3-(2-(S)-pyrrolidinylmethoxy)pyridine, in rodents and PET in nonhuman primate.

Chattopadhyay S, Xue B, Collins D, Pichika R, Bagnera R, Leslie FM, Christian BT, Shi B, Narayanan TK, Potkin SG, Mukherjee J.

J Nucl Med. 2005 Jan;46(1):130-40.

3.

Nicotinic α4β2 receptor imaging agents. Part III. Synthesis and biological evaluation of 3-(2-(S)-azetidinylmethoxy)-5-(3'-18F-fluoropropyl)pyridine (18F-nifzetidine).

Pichika R, Easwaramoorthy B, Christian BT, Shi B, Narayanan TK, Collins D, Mukherjee J.

Nucl Med Biol. 2011 Nov;38(8):1183-92. doi: 10.1016/j.nucmedbio.2011.05.005. Epub 2011 Aug 9.

4.

Nicotinic alpha4beta2 receptor imaging agents: part II. Synthesis and biological evaluation of 2-[18F]fluoro-3-[2-((S)-3-pyrrolinyl)methoxy]pyridine (18F-nifene) in rodents and imaging by PET in nonhuman primate.

Pichika R, Easwaramoorthy B, Collins D, Christian BT, Shi B, Narayanan TK, Potkin SG, Mukherjee J.

Nucl Med Biol. 2006 Apr;33(3):295-304.

PMID:
16631077
5.

Specific α4β2 nicotinic acetylcholine receptor binding of [F-18]nifene in the rhesus monkey.

Hillmer AT, Wooten DW, Moirano JM, Slesarev M, Barnhart TE, Engle JW, Nickles RJ, Murali D, Schneider ML, Mukherjee J, Christian BT.

Synapse. 2011 Dec;65(12):1309-18. doi: 10.1002/syn.20965. Epub 2011 Aug 31.

6.

Synthesis and evaluation of 2-(18)F-fluoro-5-iodo-3-[2-(S)-3,4-dehydropyrrolinylmethoxy]pyridine ((18)F-Niofene) as a potential imaging agent for nicotinic α4β2 receptors.

Kuruvilla SA, Hillmer AT, Wooten DW, Patel A, Christian BT, Mukherjee J.

Am J Nucl Med Mol Imaging. 2014 Jun 7;4(4):354-64. eCollection 2014.

7.

PET imaging of α4β2* nicotinic acetylcholine receptors: quantitative analysis of 18F-nifene kinetics in the nonhuman primate.

Hillmer AT, Wooten DW, Slesarev MS, Ahlers EO, Barnhart TE, Murali D, Schneider ML, Mukherjee J, Christian BT.

J Nucl Med. 2012 Sep;53(9):1471-80. doi: 10.2967/jnumed.112.103846. Epub 2012 Jul 31.

9.

Synthesis and characterization of binding of 5-[76Br]bromo-3-[[2(S)-azetidinyl]methoxy]pyridine, a novel nicotinic acetylcholine receptor ligand, in rat brain.

Sihver W, Fasth KJ, Horti AG, Koren AO, Bergström M, Lu L, Hagberg G, Lundqvist H, Dannals RF, London ED, Nordberg A, Långström B.

J Neurochem. 1999 Sep;73(3):1264-72.

10.

Synthesis and evaluation of 3-¹²³I-iodo-5-[2-(S)-3-pyrrolinylmethoxy]-pyridine (niodene) as a potential nicotinic α4β2 receptor imaging agent.

Pandey SK, Pan S, Kant R, Kuruvilla SA, Pan ML, Mukherjee J.

Bioorg Med Chem Lett. 2012 Dec 15;22(24):7610-4. doi: 10.1016/j.bmcl.2012.10.012. Epub 2012 Oct 10.

11.

Effect of acetylcholinesterase inhibitors on the binding of nicotinic alpha4beta2 receptor PET radiotracer, (18)F-nifene: A measure of acetylcholine competition.

Easwaramoorthy B, Pichika R, Collins D, Potkin SG, Leslie FM, Mukherjee J.

Synapse. 2007 Jan;61(1):29-36.

PMID:
17068780
12.

Evaluation of [(18)F]-(-)-norchlorofluorohomoepibatidine ([(18)F]-(-)-NCFHEB) as a PET radioligand to image the nicotinic acetylcholine receptors in non-human primates.

Bois F, Gallezot JD, Zheng MQ, Lin SF, Esterlis I, Cosgrove KP, Carson RE, Huang Y.

Nucl Med Biol. 2015 Jun;42(6):570-7. doi: 10.1016/j.nucmedbio.2014.08.003. Epub 2014 Aug 8.

13.

Synthesis and evaluation of candidate PET radioligands for corticotropin-releasing factor type-1 receptors.

Lodge NJ, Li YW, Chin FT, Dischino DD, Zoghbi SS, Deskus JA, Mattson RJ, Imaizumi M, Pieschl R, Molski TF, Fujita M, Dulac H, Zaczek R, Bronson JJ, Macor JE, Innis RB, Pike VW.

Nucl Med Biol. 2014 Jul;41(6):524-35. doi: 10.1016/j.nucmedbio.2014.03.005. Epub 2014 Mar 29.

14.

Nicotinic acetylcholine receptors in rat forebrain that bind ¹⁸F-nifene: relating PET imaging, autoradiography, and behavior.

Bieszczad KM, Kant R, Constantinescu CC, Pandey SK, Kawai HD, Metherate R, Weinberger NM, Mukherjee J.

Synapse. 2012 May;66(5):418-34. doi: 10.1002/syn.21530. Epub 2012 Feb 15.

15.

Synthesis and nicotinic acetylcholine receptor in vivo binding properties of 2-fluoro-3-[2(S)-2-azetidinylmethoxy]pyridine: a new positron emission tomography ligand for nicotinic receptors.

Doll F, Dolci L, Valette H, Hinnen F, Vaufrey F, Guenther I, Fuseau C, Coulon C, Bottlaender M, Crouzel C.

J Med Chem. 1999 Jun 17;42(12):2251-9.

PMID:
10377231
16.

PET Imaging of nicotinic acetylcholine receptors in baboons with 18F-AZAN, a radioligand with improved brain kinetics.

Kuwabara H, Wong DF, Gao Y, Valentine H, Holt DP, Ravert HT, Dannals RF, Horti AG.

J Nucl Med. 2012 Jan;53(1):121-9. doi: 10.2967/jnumed.111.092338. Epub 2011 Dec 15.

17.

2-[18F]F-A-85380: a PET radioligand for alpha4beta2 nicotinic acetylcholine receptors.

Chefer SI, Horti AG, Koren AO, Gündisch D, Links JM, Kurian V, Dannals RF, Mukhin AG, London ED.

Neuroreport. 1999 Sep 9;10(13):2715-21.

PMID:
10511429
18.

PET imaging of high-affinity α4β2 nicotinic acetylcholine receptors in humans with 18F-AZAN, a radioligand with optimal brain kinetics.

Wong DF, Kuwabara H, Kim J, Brasic JR, Chamroonrat W, Gao Y, Valentine H, Willis W, Mathur A, McCaul ME, Wand G, Gean EG, Dannals RF, Horti AG.

J Nucl Med. 2013 Aug;54(8):1308-14. doi: 10.2967/jnumed.112.108001. Epub 2013 Jun 25.

19.

Evaluation of radioiodinated 5-iodo-3-(2(S)-azetidinylmethoxy)pyridine as a ligand for SPECT investigations of brain nicotinic acetylcholine receptors.

Saji H, Ogawa M, Ueda M, Iida Y, Magata Y, Tominaga A, Kawashima H, Kitamura Y, Nakagawa M, Kiyono Y, Mukai T.

Ann Nucl Med. 2002 May;16(3):189-200.

PMID:
12126044
20.

Synthesis and biological evaluation of 18F-Norfallypride in the rodent brain using PET imaging.

Pithia N, Gulati N, Pandey S, Coleman R, Kant R, Mukherjee J.

Nucl Med Biol. 2013 Jul;40(5):697-704. doi: 10.1016/j.nucmedbio.2013.02.011. Epub 2013 Apr 4.

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