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Results: 1 to 20 of 112

1.

A novel hemoglobin-binding peptide reduces cell-free hemoglobin in murine hemolytic anemia.

Hanson MS, Xu H, Flewelen TC, Holzhauer SL, Retherford D, Jones DW, Frei AC, Pritchard KA Jr, Hillery CA, Hogg N, Wandersee NJ.

Am J Physiol Heart Circ Physiol. 2013 Jan 15;304(2):H328-36. doi: 10.1152/ajpheart.00500.2012. Epub 2012 Nov 2.

PMID:
23125208
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Arginine therapy of transgenic-knockout sickle mice improves microvascular function by reducing non-nitric oxide vasodilators, hemolysis, and oxidative stress.

Kaul DK, Zhang X, Dasgupta T, Fabry ME.

Am J Physiol Heart Circ Physiol. 2008 Jul;295(1):H39-47. doi: 10.1152/ajpheart.00162.2008. Epub 2008 May 2.

PMID:
18456737
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Nitrite reductase activity of hemoglobin as a systemic nitric oxide generator mechanism to detoxify plasma hemoglobin produced during hemolysis.

Minneci PC, Deans KJ, Shiva S, Zhi H, Banks SM, Kern S, Natanson C, Solomon SB, Gladwin MT.

Am J Physiol Heart Circ Physiol. 2008 Aug;295(2):H743-54. doi: 10.1152/ajpheart.00151.2008. Epub 2008 Jun 13.

PMID:
18552166
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Hemolysis in sickle cell mice causes pulmonary hypertension due to global impairment in nitric oxide bioavailability.

Hsu LL, Champion HC, Campbell-Lee SA, Bivalacqua TJ, Manci EA, Diwan BA, Schimel DM, Cochard AE, Wang X, Schechter AN, Noguchi CT, Gladwin MT.

Blood. 2007 Apr 1;109(7):3088-98. Erratum in: Blood. 2008 Feb 15;111(4):1772.

PMID:
17158223
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Effect of fetal hemoglobin on microvascular regulation in sickle transgenic-knockout mice.

Kaul DK, Liu XD, Chang HY, Nagel RL, Fabry ME.

J Clin Invest. 2004 Oct;114(8):1136-45.

PMID:
15489961
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Cardiopulmonary complications of sickle cell disease: role of nitric oxide and hemolytic anemia.

Gladwin MT, Kato GJ.

Hematology Am Soc Hematol Educ Program. 2005:51-7.

PMID:
16304359
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

[Pathophysiological consequences of hemolysis. Role of cell-free hemoglobin].

Misztal T, Tomasiak M.

Postepy Hig Med Dosw (Online). 2011 Sep 28;65:627-39. Review. Polish.

PMID:
22100795
[PubMed - indexed for MEDLINE]
Free Article
8.

Vascular dysfunction in a murine model of severe hemolysis.

Frei AC, Guo Y, Jones DW, Pritchard KA Jr, Fagan KA, Hogg N, Wandersee NJ.

Blood. 2008 Jul 15;112(2):398-405. doi: 10.1182/blood-2007-12-126714. Epub 2008 May 13.

PMID:
18477769
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Low micromolar intravascular cell-free hemoglobin concentration affects vascular NO bioavailability in sickle cell disease: a computational analysis.

Deonikar P, Kavdia M.

J Appl Physiol (1985). 2012 Apr;112(8):1383-92. doi: 10.1152/japplphysiol.01173.2011. Epub 2012 Jan 5.

PMID:
22223452
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

The biochemistry of nitric oxide, nitrite, and hemoglobin: role in blood flow regulation.

Gladwin MT, Crawford JH, Patel RP.

Free Radic Biol Med. 2004 Mar 15;36(6):707-17. Review.

PMID:
14990351
[PubMed - indexed for MEDLINE]
11.

Hemolysis-associated endothelial dysfunction mediated by accelerated NO inactivation by decompartmentalized oxyhemoglobin.

Minneci PC, Deans KJ, Zhi H, Yuen PS, Star RA, Banks SM, Schechter AN, Natanson C, Gladwin MT, Solomon SB.

J Clin Invest. 2005 Dec;115(12):3409-17. Epub 2005 Nov 17.

PMID:
16294219
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Computation of plasma hemoglobin nitric oxide scavenging in hemolytic anemias.

Jeffers A, Gladwin MT, Kim-Shapiro DB.

Free Radic Biol Med. 2006 Nov 15;41(10):1557-65. Epub 2006 Aug 25.

PMID:
17045924
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease.

Reiter CD, Wang X, Tanus-Santos JE, Hogg N, Cannon RO 3rd, Schechter AN, Gladwin MT.

Nat Med. 2002 Dec;8(12):1383-9. Epub 2002 Nov 11.

PMID:
12426562
[PubMed - indexed for MEDLINE]
14.

Role of the red blood cell in nitric oxide homeostasis and hypoxic vasodilation.

Gladwin MT.

Adv Exp Med Biol. 2006;588:189-205. Review.

PMID:
17089890
[PubMed - indexed for MEDLINE]
15.

The clinical sequelae of intravascular hemolysis and extracellular plasma hemoglobin: a novel mechanism of human disease.

Rother RP, Bell L, Hillmen P, Gladwin MT.

JAMA. 2005 Apr 6;293(13):1653-62. Review.

PMID:
15811985
[PubMed - indexed for MEDLINE]
16.

Antisickling property of fetal hemoglobin enhances nitric oxide bioavailability and ameliorates organ oxidative stress in transgenic-knockout sickle mice.

Dasgupta T, Fabry ME, Kaul DK.

Am J Physiol Regul Integr Comp Physiol. 2010 Feb;298(2):R394-402. doi: 10.1152/ajpregu.00611.2009. Epub 2009 Dec 9.

PMID:
20007516
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Sickle Cell Disease.

Bender MA, Douthitt Seibel G.

In: Pagon RA, Adam MP, Ardinger HH, Bird TD, Dolan CR, Fong CT, Smith RJH, Stephens K, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2014.
2003 Sep 15 [updated 2014 Oct 23].

18.

Cell-free hemoglobin and its scavenger proteins: new disease models leading the way to targeted therapies.

Schaer DJ, Buehler PW.

Cold Spring Harb Perspect Med. 2013 Jun 1;3(6). pii: a013433. doi: 10.1101/cshperspect.a013433. Review.

PMID:
23645855
[PubMed - indexed for MEDLINE]
19.

Increased mouse minor hemoglobin during erythroid stress: a model for hemoglobin regulation.

Alter BP, Campbell AS, Holland JG, Friend C.

Exp Hematol. 1982 Oct;10(9):754-60.

PMID:
6959822
[PubMed - indexed for MEDLINE]
20.

Stimulation of fetal hemoglobin synthesis in baboons by hemolysis and hypoxia.

DeSimone J, Biel SI, Heller P.

Proc Natl Acad Sci U S A. 1978 Jun;75(6):2937-40.

PMID:
96444
[PubMed - indexed for MEDLINE]
Free PMC Article
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