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Results: 1 to 20 of 100

1.

An Indian butyrylcholinesterase variant L307P is not structurally stable: a molecular dynamics simulation study.

David SM, Venkatesan SK, Boopathy R.

Chem Biol Interact. 2013 Mar 25;203(1):30-5. doi: 10.1016/j.cbi.2012.10.010. Epub 2012 Nov 1.

PMID:
23123771
[PubMed - indexed for MEDLINE]
2.

Naturally occurring mutation Leu307Pro of human butyrylcholinesterase in the Vysya community of India.

Manoharan I, Wieseler S, Layer PG, Lockridge O, Boopathy R.

Pharmacogenet Genomics. 2006 Jul;16(7):461-8.

PMID:
16788378
[PubMed - indexed for MEDLINE]
3.

Design of high-activity mutants of human butyrylcholinesterase against (-)-cocaine: structural and energetic factors affecting the catalytic efficiency.

Zheng F, Yang W, Xue L, Hou S, Liu J, Zhan CG.

Biochemistry. 2010 Oct 26;49(42):9113-9. doi: 10.1021/bi1011628.

PMID:
20886866
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

The butyrylcholinesterase K-variant shows similar cellular protein turnover and quaternary interaction to the wild-type enzyme.

Altamirano CV, Bartels CF, Lockridge O.

J Neurochem. 2000 Feb;74(2):869-77.

PMID:
10646540
[PubMed - indexed for MEDLINE]
5.
6.

Essential amino acids for the stability of human butyrylcholinesterase as predicted by CUPSAT server.

Thomas B, Boopathy R.

In Silico Biol. 2008;8(5-6):517-29.

PMID:
19374135
[PubMed - indexed for MEDLINE]
7.

Genetic analysis of a Japanese patient with butyrylcholinesterase deficiency.

Hidaka K, Iuchi I, Tomita M, Watanabe Y, Minatogawa Y, Iwasaki K, Gotoh K, Shimizu C.

Ann Hum Genet. 1997 Nov;61(Pt 6):491-6.

PMID:
9543549
[PubMed - indexed for MEDLINE]
8.

Free energy perturbation simulation on transition states and high-activity mutants of human butyrylcholinesterase for (-)-cocaine hydrolysis.

Yang W, Pan Y, Fang L, Gao D, Zheng F, Zhan CG.

J Phys Chem B. 2010 Aug 26;114(33):10889-96. doi: 10.1021/jp104989b.

PMID:
20677742
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

An improved cocaine hydrolase: the A328Y mutant of human butyrylcholinesterase is 4-fold more efficient.

Xie W, Altamirano CV, Bartels CF, Speirs RJ, Cashman JR, Lockridge O.

Mol Pharmacol. 1999 Jan;55(1):83-91.

PMID:
9882701
[PubMed - indexed for MEDLINE]
Free Article
10.

Catalytic activities of a cocaine hydrolase engineered from human butyrylcholinesterase against (+)- and (-)-cocaine.

Xue L, Hou S, Yang W, Fang L, Zheng F, Zhan CG.

Chem Biol Interact. 2013 Mar 25;203(1):57-62. doi: 10.1016/j.cbi.2012.08.003. Epub 2012 Aug 11.

PMID:
22917637
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Butyrylcholinesterase and G116H, G116S, G117H, G117N, E197Q and G117H/E197Q mutants: a molecular dynamics study.

Vyas S, Beck JM, Xia S, Zhang J, Hadad CM.

Chem Biol Interact. 2010 Sep 6;187(1-3):241-5. doi: 10.1016/j.cbi.2010.04.004. Epub 2010 May 4.

PMID:
20399202
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Characterization of a high-activity mutant of human butyrylcholinesterase against (-)-cocaine.

Yang W, Xue L, Fang L, Chen X, Zhan CG.

Chem Biol Interact. 2010 Sep 6;187(1-3):148-52. doi: 10.1016/j.cbi.2010.01.004. Epub 2010 Jan 11.

PMID:
20060817
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Resistance of butyrylcholinesterase to inactivation by ultrasound: effects of ultrasound on catalytic activity and subunit association.

Froment MT, Lockridge O, Masson P.

Biochim Biophys Acta. 1998 Sep 8;1387(1-2):53-64.

PMID:
9748500
[PubMed - indexed for MEDLINE]
Free Article
14.

Amino-acid mutations to extend the biological half-life of a therapeutically valuable mutant of human butyrylcholinesterase.

Fang L, Hou S, Xue L, Zheng F, Zhan CG.

Chem Biol Interact. 2014 May 5;214:18-25. doi: 10.1016/j.cbi.2014.02.007. Epub 2014 Feb 25.

PMID:
24582612
[PubMed - indexed for MEDLINE]
15.

Characterization of an unstable variant (BChE115D) of human butyrylcholinesterase.

Primo-Parmo SL, Lightstone H, La Du BN.

Pharmacogenetics. 1997 Feb;7(1):27-34.

PMID:
9110359
[PubMed - indexed for MEDLINE]
16.

Active site gating and substrate specificity of butyrylcholinesterase and acetylcholinesterase: insights from molecular dynamics simulations.

Fang L, Pan Y, Muzyka JL, Zhan CG.

J Phys Chem B. 2011 Jul 14;115(27):8797-805. doi: 10.1021/jp112030p. Epub 2011 Jun 17.

PMID:
21682268
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Intramolecular relationships in cholinesterases revealed by oocyte expression of site-directed and natural variants of human BCHE.

Neville LF, Gnatt A, Loewenstein Y, Seidman S, Ehrlich G, Soreq H.

EMBO J. 1992 Apr;11(4):1641-9.

PMID:
1373381
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Molecular dynamics simulation of cocaine binding with human butyrylcholinesterase and its mutants.

Hamza A, Cho H, Tai HH, Zhan CG.

J Phys Chem B. 2005 Mar 17;109(10):4776-82.

PMID:
16851561
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Asp7O in the peripheral anionic site of human butyrylcholinesterase.

Masson P, Froment MT, Bartels CF, Lockridge O.

Eur J Biochem. 1996 Jan 15;235(1-2):36-48.

PMID:
8631355
[PubMed - indexed for MEDLINE]
Free Article
20.

Kinetic analysis of effector modulation of butyrylcholinesterase-catalysed hydrolysis of acetanilides and homologous esters.

Masson P, Froment MT, Gillon E, Nachon F, Lockridge O, Schopfer LM.

FEBS J. 2008 May;275(10):2617-31. doi: 10.1111/j.1742-4658.2008.06409.x. Epub 2008 Apr 15.

PMID:
18422653
[PubMed - indexed for MEDLINE]

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