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Results: 1 to 20 of 121

1.

Mitochondrial dysfunction causing cardiac sodium channel downregulation in cardiomyopathy.

Liu M, Gu L, Sulkin MS, Liu H, Jeong EM, Greener I, Xie A, Efimov IR, Dudley SC Jr.

J Mol Cell Cardiol. 2013 Jan;54:25-34. doi: 10.1016/j.yjmcc.2012.10.011. Epub 2012 Nov 1.

PMID:
23123323
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Reactive oxygen species originating from mitochondria regulate the cardiac sodium channel.

Liu M, Liu H, Dudley SC Jr.

Circ Res. 2010 Oct 15;107(8):967-74. doi: 10.1161/CIRCRESAHA.110.220673. Epub 2010 Aug 19.

PMID:
20724705
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Cardiac Na+ current regulation by pyridine nucleotides.

Liu M, Sanyal S, Gao G, Gurung IS, Zhu X, Gaconnet G, Kerchner LJ, Shang LL, Huang CL, Grace A, London B, Dudley SC Jr.

Circ Res. 2009 Oct 9;105(8):737-45. doi: 10.1161/CIRCRESAHA.109.197277. Epub 2009 Sep 10.

PMID:
19745168
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Elevated cytosolic Na+ increases mitochondrial formation of reactive oxygen species in failing cardiac myocytes.

Kohlhaas M, Liu T, Knopp A, Zeller T, Ong MF, Böhm M, O'Rourke B, Maack C.

Circulation. 2010 Apr 13;121(14):1606-13. doi: 10.1161/CIRCULATIONAHA.109.914911. Epub 2010 Mar 29.

PMID:
20351235
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Fibroblast growth factor homologous factor 13 regulates Na+ channels and conduction velocity in murine hearts.

Wang C, Hennessey JA, Kirkton RD, Wang C, Graham V, Puranam RS, Rosenberg PB, Bursac N, Pitt GS.

Circ Res. 2011 Sep 16;109(7):775-82. doi: 10.1161/CIRCRESAHA.111.247957. Epub 2011 Aug 4.

PMID:
21817159
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

L-type Ca(2+) channel contributes to alterations in mitochondrial calcium handling in the mdx ventricular myocyte.

Viola HM, Davies SM, Filipovska A, Hool LC.

Am J Physiol Heart Circ Physiol. 2013 Mar 15;304(6):H767-75. doi: 10.1152/ajpheart.00700.2012. Epub 2013 Jan 18.

PMID:
23335798
[PubMed - indexed for MEDLINE]
Free Article
7.

Intercalated disc abnormalities, reduced Na(+) current density, and conduction slowing in desmoglein-2 mutant mice prior to cardiomyopathic changes.

Rizzo S, Lodder EM, Verkerk AO, Wolswinkel R, Beekman L, Pilichou K, Basso C, Remme CA, Thiene G, Bezzina CR.

Cardiovasc Res. 2012 Sep 1;95(4):409-18. doi: 10.1093/cvr/cvs219. Epub 2012 Jul 3.

PMID:
22764152
[PubMed - indexed for MEDLINE]
Free Article
8.

Regulation of the Na+/Ca2+ exchanger by pyridine nucleotide redox potential in ventricular myocytes.

Liu T, O'Rourke B.

J Biol Chem. 2013 Nov 1;288(44):31984-92. doi: 10.1074/jbc.M113.496588. Epub 2013 Sep 17.

PMID:
24045952
[PubMed - indexed for MEDLINE]
9.

Enhancing mitochondrial Ca2+ uptake in myocytes from failing hearts restores energy supply and demand matching.

Liu T, O'Rourke B.

Circ Res. 2008 Aug 1;103(3):279-88. doi: 10.1161/CIRCRESAHA.108.175919. Epub 2008 Jul 3.

PMID:
18599868
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Dystrophic cardiomyopathy: amplification of cellular damage by Ca2+ signalling and reactive oxygen species-generating pathways.

Jung C, Martins AS, Niggli E, Shirokova N.

Cardiovasc Res. 2008 Mar 1;77(4):766-73. Epub 2007 Dec 4.

PMID:
18056762
[PubMed - indexed for MEDLINE]
Free Article
11.

Ranolazine improves cardiac diastolic dysfunction through modulation of myofilament calcium sensitivity.

Lovelock JD, Monasky MM, Jeong EM, Lardin HA, Liu H, Patel BG, Taglieri DM, Gu L, Kumar P, Pokhrel N, Zeng D, Belardinelli L, Sorescu D, Solaro RJ, Dudley SC Jr.

Circ Res. 2012 Mar 16;110(6):841-50. doi: 10.1161/CIRCRESAHA.111.258251. Epub 2012 Feb 16.

PMID:
22343711
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Antiarrhythmic effects of (-)-epicatechin-3-gallate, a novel sodium channel agonist in cultured neonatal rat ventricular myocytes.

Wu AZ, Loh SH, Cheng TH, Lu HH, Lin CI.

Biochem Pharmacol. 2013 Jan 1;85(1):69-80. doi: 10.1016/j.bcp.2012.10.003. Epub 2012 Oct 29.

PMID:
23116965
[PubMed - indexed for MEDLINE]
13.

Ranolazine improves abnormal repolarization and contraction in left ventricular myocytes of dogs with heart failure by inhibiting late sodium current.

Undrovinas AI, Belardinelli L, Undrovinas NA, Sabbah HN.

J Cardiovasc Electrophysiol. 2006 May;17 Suppl 1:S169-S177.

PMID:
16686675
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Mitochondrial production of reactive oxygen species contributes to the β-adrenergic stimulation of mouse cardiomycytes.

Andersson DC, Fauconnier J, Yamada T, Lacampagne A, Zhang SJ, Katz A, Westerblad H.

J Physiol. 2011 Apr 1;589(Pt 7):1791-801. doi: 10.1113/jphysiol.2010.202838. Epub 2011 Feb 28.

PMID:
21486840
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Synchronized whole cell oscillations in mitochondrial metabolism triggered by a local release of reactive oxygen species in cardiac myocytes.

Aon MA, Cortassa S, Marbán E, O'Rourke B.

J Biol Chem. 2003 Nov 7;278(45):44735-44. Epub 2003 Aug 20.

PMID:
12930841
[PubMed - indexed for MEDLINE]
Free Article
16.

Loss of function of hNav1.5 by a ZASP1 mutation associated with intraventricular conduction disturbances in left ventricular noncompaction.

Xi Y, Ai T, De Lange E, Li Z, Wu G, Brunelli L, Kyle WB, Turker I, Cheng J, Ackerman MJ, Kimura A, Weiss JN, Qu Z, Kim JJ, Faulkner G, Vatta M.

Circ Arrhythm Electrophysiol. 2012 Oct;5(5):1017-26. doi: 10.1161/CIRCEP.111.969220. Epub 2012 Aug 28.

PMID:
22929165
[PubMed - indexed for MEDLINE]
Free Article
17.

A null mutation of the neuronal sodium channel NaV1.6 disrupts action potential propagation and excitation-contraction coupling in the mouse heart.

Noujaim SF, Kaur K, Milstein M, Jones JM, Furspan P, Jiang D, Auerbach DS, Herron T, Meisler MH, Jalife J.

FASEB J. 2012 Jan;26(1):63-72. doi: 10.1096/fj.10-179770. Epub 2011 Sep 24.

PMID:
21948246
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Cardiomyocyte deletion of mitofusin-1 leads to mitochondrial fragmentation and improves tolerance to ROS-induced mitochondrial dysfunction and cell death.

Papanicolaou KN, Ngoh GA, Dabkowski ER, O'Connell KA, Ribeiro RF Jr, Stanley WC, Walsh K.

Am J Physiol Heart Circ Physiol. 2012 Jan 1;302(1):H167-79. doi: 10.1152/ajpheart.00833.2011. Epub 2011 Oct 28.

PMID:
22037195
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

About half of the late sodium current in cardiac myocytes from dog ventricle is due to non-cardiac-type Na(+) channels.

Biet M, Barajas-Martínez H, Ton AT, Delabre JF, Morin N, Dumaine R.

J Mol Cell Cardiol. 2012 Nov;53(5):593-8. doi: 10.1016/j.yjmcc.2012.06.012. Epub 2012 Jun 30.

PMID:
22759452
[PubMed - indexed for MEDLINE]
20.

The cardiomyocyte molecular clock, regulation of Scn5a, and arrhythmia susceptibility.

Schroder EA, Lefta M, Zhang X, Bartos DC, Feng HZ, Zhao Y, Patwardhan A, Jin JP, Esser KA, Delisle BP.

Am J Physiol Cell Physiol. 2013 May 15;304(10):C954-65. doi: 10.1152/ajpcell.00383.2012. Epub 2013 Jan 30.

PMID:
23364267
[PubMed - indexed for MEDLINE]
Free PMC Article

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