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Items: 1 to 20 of 111

1.

Normal spastin gene dosage is specifically required for axon regeneration.

Stone MC, Rao K, Gheres KW, Kim S, Tao J, La Rochelle C, Folker CT, Sherwood NT, Rolls MM.

Cell Rep. 2012 Nov 29;2(5):1340-50. doi: 10.1016/j.celrep.2012.09.032. Epub 2012 Nov 1.

2.

Drosophila spastin regulates synaptic microtubule networks and is required for normal motor function.

Sherwood NT, Sun Q, Xue M, Zhang B, Zinn K.

PLoS Biol. 2004 Dec;2(12):e429. Epub 2004 Nov 30.

3.

Katanin p60-like1 promotes microtubule growth and terminal dendrite stability in the larval class IV sensory neurons of Drosophila.

Stewart A, Tsubouchi A, Rolls MM, Tracey WD, Sherwood NT.

J Neurosci. 2012 Aug 22;32(34):11631-42. doi: 10.1523/JNEUROSCI.0729-12.2012.

4.

Structural basis of microtubule severing by the hereditary spastic paraplegia protein spastin.

Roll-Mecak A, Vale RD.

Nature. 2008 Jan 17;451(7176):363-7. doi: 10.1038/nature06482.

5.

Global up-regulation of microtubule dynamics and polarity reversal during regeneration of an axon from a dendrite.

Stone MC, Nguyen MM, Tao J, Allender DL, Rolls MM.

Mol Biol Cell. 2010 Mar 1;21(5):767-77. doi: 10.1091/mbc.E09-11-0967. Epub 2010 Jan 6.

6.

Drosophila IKK-related kinase Ik2 and Katanin p60-like 1 regulate dendrite pruning of sensory neuron during metamorphosis.

Lee HH, Jan LY, Jan YN.

Proc Natl Acad Sci U S A. 2009 Apr 14;106(15):6363-8. doi: 10.1073/pnas.0902051106. Epub 2009 Mar 27.

7.

Genetic and chemical modulation of spastin-dependent axon outgrowth in zebrafish embryos indicates a role for impaired microtubule dynamics in hereditary spastic paraplegia.

Butler R, Wood JD, Landers JA, Cunliffe VT.

Dis Model Mech. 2010 Nov-Dec;3(11-12):743-51. doi: 10.1242/dmm.004002. Epub 2010 Sep 9.

8.

The microtubule-severing protein Spastin is essential for axon outgrowth in the zebrafish embryo.

Wood JD, Landers JA, Bingley M, McDermott CJ, Thomas-McArthur V, Gleadall LJ, Shaw PJ, Cunliffe VT.

Hum Mol Genet. 2006 Sep 15;15(18):2763-71. Epub 2006 Aug 7.

9.

Recognition of C-terminal amino acids in tubulin by pore loops in Spastin is important for microtubule severing.

White SR, Evans KJ, Lary J, Cole JL, Lauring B.

J Cell Biol. 2007 Mar 26;176(7):995-1005.

10.

Linking axonal degeneration to microtubule remodeling by Spastin-mediated microtubule severing.

Evans KJ, Gomes ER, Reisenweber SM, Gundersen GG, Lauring BP.

J Cell Biol. 2005 Feb 14;168(4):599-606.

11.

The microtubule-severing proteins spastin and katanin participate differently in the formation of axonal branches.

Yu W, Qiang L, Solowska JM, Karabay A, Korulu S, Baas PW.

Mol Biol Cell. 2008 Apr;19(4):1485-98. doi: 10.1091/mbc.E07-09-0878. Epub 2008 Jan 30.

12.

Rear-side localization of the centrosome in migrating neuroblastoma Neuro-2a cells and its roles in process elongation.

Kawabata W, Yonezawa S, Hayashi K.

Dev Neurosci. 2012;34(1):20-9. doi: 10.1159/000338599. Epub 2012 Jun 1.

PMID:
22677609
14.

Pathogenic mutation of spastin has gain-of-function effects on microtubule dynamics.

Solowska JM, D'Rozario M, Jean DC, Davidson MW, Marenda DR, Baas PW.

J Neurosci. 2014 Jan 29;34(5):1856-67. doi: 10.1523/JNEUROSCI.3309-13.2014.

15.

Spastin-interacting protein NA14/SSNA1 functions in cytokinesis and axon development.

Goyal U, Renvoisé B, Chang J, Blackstone C.

PLoS One. 2014 Nov 12;9(11):e112428. doi: 10.1371/journal.pone.0112428. eCollection 2014.

16.

Pleiotropic effects of spastin on neurite growth depending on expression levels.

Riano E, Martignoni M, Mancuso G, Cartelli D, Crippa F, Toldo I, Siciliano G, Di Bella D, Taroni F, Bassi MT, Cappelletti G, Rugarli EI.

J Neurochem. 2009 Mar;108(5):1277-88. doi: 10.1111/j.1471-4159.2009.05875.x. Epub 2009 Jan 29.

17.

Kinesin-1-powered microtubule sliding initiates axonal regeneration in Drosophila cultured neurons.

Lu W, Lakonishok M, Gelfand VI.

Mol Biol Cell. 2015 Apr 1;26(7):1296-307. doi: 10.1091/mbc.E14-10-1423. Epub 2015 Feb 5.

18.

Regeneration of Drosophila sensory neuron axons and dendrites is regulated by the Akt pathway involving Pten and microRNA bantam.

Song Y, Ori-McKenney KM, Zheng Y, Han C, Jan LY, Jan YN.

Genes Dev. 2012 Jul 15;26(14):1612-25. doi: 10.1101/gad.193243.112. Epub 2012 Jul 3.

19.
20.

Axon injury and stress trigger a microtubule-based neuroprotective pathway.

Chen L, Stone MC, Tao J, Rolls MM.

Proc Natl Acad Sci U S A. 2012 Jul 17;109(29):11842-7. doi: 10.1073/pnas.1121180109. Epub 2012 Jun 25.

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