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Results: 1 to 20 of 157

1.

Gabapentin enacarbil in Japanese patients with restless legs syndrome: a 12-week, randomized, double-blind, placebo-controlled, parallel-group study.

Inoue Y, Hirata K, Uchimura N, Kuroda K, Hattori N, Takeuchi M.

Curr Med Res Opin. 2013 Jan;29(1):13-21. doi: 10.1185/03007995.2012.746217. Epub 2012 Nov 30.

PMID:
23121149
[PubMed - indexed for MEDLINE]
2.

A randomized, double-blind, placebo-controlled study to assess the efficacy and tolerability of gabapentin enacarbil in subjects with restless legs syndrome.

Lee DO, Ziman RB, Perkins AT, Poceta JS, Walters AS, Barrett RW; XP053 Study Group.

J Clin Sleep Med. 2011 Jun 15;7(3):282-92. doi: 10.5664/JCSM.1074.

PMID:
21677899
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Dose response of Gabapentin Enacarbil versus placebo in subjects with moderate-to-severe primary restless legs syndrome: an integrated analysis of three 12-week studies.

VanMeter SA, Kavanagh ST, Warren S, Barrett RW.

CNS Drugs. 2012 Sep 1;26(9):773-80. doi: 10.2165/11634870-000000000-00000.

PMID:
22849331
[PubMed - indexed for MEDLINE]
4.

Long-term efficacy and safety of gabapentin enacarbil in Japanese restless legs syndrome patients.

Inoue Y, Uchimura N, Kuroda K, Hirata K, Hattori N.

Prog Neuropsychopharmacol Biol Psychiatry. 2012 Mar 30;36(2):251-7. doi: 10.1016/j.pnpbp.2011.10.009. Epub 2011 Oct 19.

PMID:
22036917
[PubMed - indexed for MEDLINE]
5.

Gabapentin enacarbil in restless legs syndrome: a phase 2b, 2-week, randomized, double-blind, placebo-controlled trial.

Walters AS, Ondo WG, Kushida CA, Becker PM, Ellenbogen AL, Canafax DM, Barrett RW; XP045 Study Group.

Clin Neuropharmacol. 2009 Nov-Dec;32(6):311-20. doi: 10.1097/WNF.0b013e3181b3ab16.

PMID:
19667976
[PubMed - indexed for MEDLINE]
6.

A randomized, double-blind, placebo-controlled, dose-response study to assess the pharmacokinetics, efficacy, and safety of gabapentin enacarbil in subjects with restless legs syndrome.

Lal R, Ellenbogen A, Chen D, Zomorodi K, Atluri H, Luo W, Tovera J, Hurt J, Bonzo D, Lassauzet ML, Vu A, Cundy KC.

Clin Neuropharmacol. 2012 Jul-Aug;35(4):165-73. doi: 10.1097/WNF.0b013e318259eac8.

PMID:
22664749
[PubMed - indexed for MEDLINE]
7.

Long-term maintenance treatment of restless legs syndrome with gabapentin enacarbil: a randomized controlled study.

Bogan RK, Bornemann MA, Kushida CA, Trân PV, Barrett RW; XP060 Study Group.

Mayo Clin Proc. 2010 Jun;85(6):512-21. doi: 10.4065/mcp.2009.0700. Erratum in: Mayo Clin Proc. 2010 Jul;85(7):693-4.

PMID:
20511481
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Randomized, double-blind, placebo-controlled study of XP13512/GSK1838262 in patients with RLS.

Kushida CA, Becker PM, Ellenbogen AL, Canafax DM, Barrett RW; XP052 Study Group.

Neurology. 2009 Feb 3;72(5):439-46. doi: 10.1212/01.wnl.0000341770.91926.cc.

PMID:
19188575
[PubMed - indexed for MEDLINE]
9.

Gabapentin enacarbil: in patients with restless legs syndrome.

Scott LJ.

CNS Drugs. 2012 Dec;26(12):1073-83. doi: 10.1007/s40263-012-0020-3. Review. Erratum in: CNS Drugs. 2013 Feb;27(2):163-4. CNS Drugs. 2013 Jan;27(1):81.

PMID:
23179641
[PubMed - indexed for MEDLINE]
10.

Randomized polysomnography study of gabapentin enacarbil in subjects with restless legs syndrome.

Winkelman JW, Bogan RK, Schmidt MH, Hudson JD, DeRossett SE, Hill-Zabala CE.

Mov Disord. 2011 Sep;26(11):2065-72. doi: 10.1002/mds.23771. Epub 2011 May 24.

PMID:
21611981
[PubMed - indexed for MEDLINE]
11.

Population pharmacokinetics and pharmacodynamics of gabapentin after administration of gabapentin enacarbil.

Lal R, Sukbuntherng J, Luo W, Tovera J, Lassauzet ML, Cundy KC.

J Clin Pharmacol. 2013 Jan;53(1):29-40. doi: 10.1177/0091270012439209. Epub 2013 Jan 24.

PMID:
23400741
[PubMed - indexed for MEDLINE]
12.

A randomized, double-blind, placebo-controlled, crossover study of XP13512/GSK1838262 in the treatment of patients with primary restless legs syndrome.

Kushida CA, Walters AS, Becker P, Thein SG, Perkins AT, Roth T, Canafax D, Barrett RW; XP021 Study Group.

Sleep. 2009 Feb;32(2):159-68.

PMID:
19238802
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

A randomized, double-blind, 6-week, dose-ranging study of pregabalin in patients with restless legs syndrome.

Allen R, Chen C, Soaita A, Wohlberg C, Knapp L, Peterson BT, García-Borreguero D, Miceli J.

Sleep Med. 2010 Jun;11(6):512-9. doi: 10.1016/j.sleep.2010.03.003. Epub 2010 May 13.

PMID:
20466589
[PubMed - indexed for MEDLINE]
14.

Ropinirole in patients with restless legs syndrome and baseline IRLS total scores ≥ 24: efficacy and tolerability in a 26-week, double-blind, parallel-group, placebo-controlled study followed by a 40-week open-label extension.

Giorgi L, Asgharian A, Hunter B.

Clin Ther. 2013 Sep;35(9):1321-36. doi: 10.1016/j.clinthera.2013.06.016. Epub 2013 Aug 9.

PMID:
23938061
[PubMed - indexed for MEDLINE]
15.

Treatment of restless legs syndrome with pregabalin: a double-blind, placebo-controlled study.

Garcia-Borreguero D, Larrosa O, Williams AM, Albares J, Pascual M, Palacios JC, Fernandez C.

Neurology. 2010 Jun 8;74(23):1897-904. doi: 10.1212/WNL.0b013e3181e1ce73. Epub 2010 Apr 28.

PMID:
20427750
[PubMed - indexed for MEDLINE]
16.

Cardiac repolarization with Gabapentin enacarbil in a randomized, double-blind, placebo- and active-controlled, crossover thorough QT/QTc study in healthy adults.

Davy M, Upward J, Arumugham T, Twomey C, Chen C, Stier B.

Clin Ther. 2013 Dec;35(12):1964-74. doi: 10.1016/j.clinthera.2013.10.011. Epub 2013 Nov 28.

PMID:
24290737
[PubMed - indexed for MEDLINE]
17.

Validation of the post sleep questionnaire for assessing subjects with restless legs syndrome: results from two double-blind, multicenter, placebo-controlled clinical trials.

Canafax DM, Bhanegaonkar A, Bharmal M, Calloway M.

BMC Neurol. 2011 Apr 28;11:48. doi: 10.1186/1471-2377-11-48.

PMID:
21527006
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Efficacy and safety of rotigotine in Japanese patients with restless legs syndrome: a phase 3, multicenter, randomized, placebo-controlled, double-blind, parallel-group study.

Inoue Y, Shimizu T, Hirata K, Uchimura N, Ishigooka J, Oka Y, Ikeda J, Tomida T, Hattori N; Rotigotine Trial Group.

Sleep Med. 2013 Nov;14(11):1085-91. doi: 10.1016/j.sleep.2013.07.007. Epub 2013 Aug 21.

PMID:
24055212
[PubMed - indexed for MEDLINE]
19.

Ropinirole is effective in the treatment of restless legs syndrome. TREAT RLS 2: a 12-week, double-blind, randomized, parallel-group, placebo-controlled study.

Walters AS, Ondo WG, Dreykluft T, Grunstein R, Lee D, Sethi K; TREAT RLS 2 (Therapy with Ropinirole: Efficacy And Tolerability in RLS 2) Study Group.

Mov Disord. 2004 Dec;19(12):1414-23.

PMID:
15390050
[PubMed - indexed for MEDLINE]
20.

Ropinirole in the treatment of patients with restless legs syndrome: a US-based randomized, double-blind, placebo-controlled clinical trial.

Bogan RK, Fry JM, Schmidt MH, Carson SW, Ritchie SY; TREAT RLS US Study Group.

Mayo Clin Proc. 2006 Jan;81(1):17-27.

PMID:
16438474
[PubMed - indexed for MEDLINE]
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