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Items: 1 to 20 of 108

1.

Alcohol-induced one-carbon metabolism impairment promotes dysfunction of DNA base excision repair in adult brain.

Fowler AK, Hewetson A, Agrawal RG, Dagda M, Dagda R, Moaddel R, Balbo S, Sanghvi M, Chen Y, Hogue RJ, Bergeson SE, Henderson GI, Kruman II.

J Biol Chem. 2012 Dec 21;287(52):43533-42. doi: 10.1074/jbc.M112.401497. Epub 2012 Nov 1.

2.

Differential sensitivity of prefrontal cortex and hippocampus to alcohol-induced toxicity.

Fowler AK, Thompson J, Chen L, Dagda M, Dertien J, Dossou KS, Moaddel R, Bergeson SE, Kruman II.

PLoS One. 2014 Sep 4;9(9):e106945. doi: 10.1371/journal.pone.0106945. eCollection 2014.

3.

DNA damage and neurotoxicity of chronic alcohol abuse.

Kruman II, Henderson GI, Bergeson SE.

Exp Biol Med (Maywood). 2012 Jul;237(7):740-7. doi: 10.1258/ebm.2012.011421. Epub 2012 Jul 24. Review.

4.

Alcohol induces DNA damage and the Fanconi anemia D2 protein implicating FANCD2 in the DNA damage response pathways in brain.

Rulten SL, Hodder E, Ripley TL, Stephens DN, Mayne LV.

Alcohol Clin Exp Res. 2008 Jul;32(7):1186-96. doi: 10.1111/j.1530-0277.2008.00673.x.

PMID:
18482162
5.

Impaired one carbon metabolism and DNA methylation in alcohol toxicity.

Kruman II, Fowler AK.

J Neurochem. 2014 Jun;129(5):770-80. doi: 10.1111/jnc.12677. Epub 2014 Mar 7. Review.

6.

Stability of DNA methylation patterns in mouse spermatogonia under conditions of MTHFR deficiency and methionine supplementation.

Garner JL, Niles KM, McGraw S, Yeh JR, Cushnie DW, Hermo L, Nagano MC, Trasler JM.

Biol Reprod. 2013 Nov 27;89(5):125. doi: 10.1095/biolreprod.113.109066. Print 2013 Nov.

7.

One-carbon metabolism, spermatogenesis, and male infertility.

Singh K, Jaiswal D.

Reprod Sci. 2013 Jun;20(6):622-30. doi: 10.1177/1933719112459232. Epub 2012 Nov 8. Review.

PMID:
23138010
8.

Alcohol intake and methylenetetrahydrofolate reductase polymorphism modify the relation of folate intake to plasma homocysteine.

Chiuve SE, Giovannucci EL, Hankinson SE, Hunter DJ, Stampfer MJ, Willett WC, Rimm EB.

Am J Clin Nutr. 2005 Jul;82(1):155-62.

9.

The association between MTHFR 677C>T genotype and folate status and genomic and gene-specific DNA methylation in the colon of individuals without colorectal neoplasia.

Hanks J, Ayed I, Kukreja N, Rogers C, Harris J, Gheorghiu A, Liu CL, Emery P, Pufulete M.

Am J Clin Nutr. 2013 Dec;98(6):1564-74. doi: 10.3945/ajcn.113.061432. Epub 2013 Oct 9.

11.
12.

Methylenetetrahydrofolate reductase 677C-->T polymorphism affects DNA methylation in response to controlled folate intake in young women.

Shelnutt KP, Kauwell GP, Gregory JF 3rd, Maneval DR, Quinlivan EP, Theriaque DW, Henderson GN, Bailey LB.

J Nutr Biochem. 2004 Sep;15(9):554-60.

PMID:
15350988
13.

Methylenetetrahydrofolate reductase, common polymorphisms, and relation to disease.

Thomas P, Fenech M.

Vitam Horm. 2008;79:375-92. doi: 10.1016/S0083-6729(08)00413-5.

PMID:
18804702
14.

Evaluation of cell proliferation, apoptosis, and DNA-repair genes as potential biomarkers for ethanol-induced CNS alterations.

Hicks SD, Lewis L, Ritchie J, Burke P, Abdul-Malak Y, Adackapara N, Canfield K, Shwarts E, Gentile K, Meszaros ZS, Middleton FA.

BMC Neurosci. 2012 Oct 25;13:128. doi: 10.1186/1471-2202-13-128.

15.

Ethanol-induced oxidative stress and mitochondrial dysfunction in rat placenta: relevance to pregnancy loss.

Gundogan F, Elwood G, Mark P, Feijoo A, Longato L, Tong M, de la Monte SM.

Alcohol Clin Exp Res. 2010 Mar 1;34(3):415-23. doi: 10.1111/j.1530-0277.2009.01106.x. Epub 2009 Dec 17.

16.

High folic acid consumption leads to pseudo-MTHFR deficiency, altered lipid metabolism, and liver injury in mice.

Christensen KE, Mikael LG, Leung KY, Lévesque N, Deng L, Wu Q, Malysheva OV, Best A, Caudill MA, Greene ND, Rozen R.

Am J Clin Nutr. 2015 Mar;101(3):646-58. doi: 10.3945/ajcn.114.086603. Epub 2015 Jan 7.

17.

Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer.

Ma J, Stampfer MJ, Giovannucci E, Artigas C, Hunter DJ, Fuchs C, Willett WC, Selhub J, Hennekens CH, Rozen R.

Cancer Res. 1997 Mar 15;57(6):1098-102.

18.

Pro- and anti-inflammatory gene expression in the murine small intestine and liver after chronic exposure to alcohol.

Fleming S, Toratani S, Shea-Donohue T, Kashiwabara Y, Vogel SN, Metcalf ES.

Alcohol Clin Exp Res. 2001 Apr;25(4):579-89.

PMID:
11329499
19.

The etiology of alcohol-induced breast cancer.

Dumitrescu RG, Shields PG.

Alcohol. 2005 Apr;35(3):213-25. Review.

PMID:
16054983
20.

Susceptibility to intestinal tumorigenesis in folate-deficient mice may be influenced by variation in one-carbon metabolism and DNA repair.

Knock E, Deng L, Krupenko N, Mohan RD, Wu Q, Leclerc D, Gupta S, Elmore CL, Kruger W, Tini M, Rozen R.

J Nutr Biochem. 2011 Nov;22(11):1022-9. doi: 10.1016/j.jnutbio.2010.07.015. Epub 2010 Dec 28.

PMID:
21193302
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