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Items: 1 to 20 of 80

1.

Dysregulated Tim-3 expression and its correlation with imbalanced CD4 helper T cell function in ulcerative colitis.

Shi F, Guo X, Jiang X, Zhou P, Xiao Y, Zhou T, Chen G, Zhao Z, Xiao H, Hou C, Li X, Yang X, Wang R, Feng J, Shen B, Li Y, Han G.

Clin Immunol. 2012 Dec;145(3):230-40. doi: 10.1016/j.clim.2012.09.001. Epub 2012 Sep 18.

PMID:
23117395
2.

Regulation of gut inflammation and th17 cell response by interleukin-21.

Fina D, Sarra M, Fantini MC, Rizzo A, Caruso R, Caprioli F, Stolfi C, Cardolini I, Dottori M, Boirivant M, Pallone F, Macdonald TT, Monteleone G.

Gastroenterology. 2008 Apr;134(4):1038-48. doi: 10.1053/j.gastro.2008.01.041. Epub 2008 Jan 17.

PMID:
18395085
3.

CCL17 promotes intestinal inflammation in mice and counteracts regulatory T cell-mediated protection from colitis.

Heiseke AF, Faul AC, Lehr HA, Förster I, Schmid RM, Krug AB, Reindl W.

Gastroenterology. 2012 Feb;142(2):335-45. doi: 10.1053/j.gastro.2011.10.027. Epub 2011 Nov 2.

PMID:
22057112
4.

IL23 differentially regulates the Th1/Th17 balance in ulcerative colitis and Crohn's disease.

Kobayashi T, Okamoto S, Hisamatsu T, Kamada N, Chinen H, Saito R, Kitazume MT, Nakazawa A, Sugita A, Koganei K, Isobe K, Hibi T.

Gut. 2008 Dec;57(12):1682-9. doi: 10.1136/gut.2007.135053. Epub 2008 Jul 24.

PMID:
18653729
5.

Stable form of galectin-9, a Tim-3 ligand, inhibits contact hypersensitivity and psoriatic reactions: a potent therapeutic tool for Th1- and/or Th17-mediated skin inflammation.

Niwa H, Satoh T, Matsushima Y, Hosoya K, Saeki K, Niki T, Hirashima M, Yokozeki H.

Clin Immunol. 2009 Aug;132(2):184-94. doi: 10.1016/j.clim.2009.04.012. Epub 2009 May 23.

PMID:
19464955
6.

Galectin-9 and T cell immunoglobulin mucin-3 pathway is a therapeutic target for type 1 diabetes.

Kanzaki M, Wada J, Sugiyama K, Nakatsuka A, Teshigawara S, Murakami K, Inoue K, Terami T, Katayama A, Eguchi J, Akiba H, Yagita H, Makino H.

Endocrinology. 2012 Feb;153(2):612-20. doi: 10.1210/en.2011-1579. Epub 2011 Dec 20.

PMID:
22186414
7.

Intestinal antiinflammatory effects of thiazolidenedione peroxisome proliferator-activated receptor-gamma ligands on T helper type 1 chemokine regulation include nontranscriptional control mechanisms.

Schaefer KL, Denevich S, Ma C, Cooley SR, Nakajima A, Wada K, Schlezinger J, Sherr D, Saubermann LJ.

Inflamm Bowel Dis. 2005 Mar;11(3):244-52.

PMID:
15735430
8.

Galectin-9 significantly prolongs the survival of fully mismatched cardiac allografts in mice.

He W, Fang Z, Wang F, Wu K, Xu Y, Zhou H, Du D, Gao Y, Zhang WN, Niki T, Hirashima M, Yuan J, Chen ZK.

Transplantation. 2009 Sep 27;88(6):782-90. doi: 10.1097/TP.0b013e3181b47f25.

PMID:
19920777
9.

Altered expression of T cell immunoglobulin-mucin (TIM) molecules in bronchoalveolar lavage CD4+ T cells in sarcoidosis.

Idali F, Wahlström J, Dahlberg B, Khademi M, Olsson T, Eklund A, Grunewald J.

Respir Res. 2009 May 29;10:42. doi: 10.1186/1465-9921-10-42.

10.

Tim-3-Galectin-9 pathway involves the suppression induced by CD4+CD25+ regulatory T cells.

Wang F, Wan L, Zhang C, Zheng X, Li J, Chen ZK.

Immunobiology. 2009;214(5):342-9. doi: 10.1016/j.imbio.2008.10.007. Epub 2008 Dec 6.

PMID:
19362679
11.

Expression of the Th1-specific cell-surface protein Tim-3 increases in a murine model of atopic asthma.

Hu WK, Lu XX, Yang S, Xu GP, Lan F, Chen SX, Ni W, Xiong WN, Xiong SD.

J Asthma. 2009 Nov;46(9):872-7. doi: 10.3109/02770900903199953.

PMID:
19905911
12.

Tim-2 up-regulation and galectin-9-Tim-3 pathway activation in Th2-biased response in Schistosoma japonicum infection in mice.

Qi Y, Song XR, Shen JL, Xu YH, Shen Q, Luo QL, Zhong ZR, Wang W, Chu DY, Song WJ.

Immunol Lett. 2012 May 30;144(1-2):60-6. doi: 10.1016/j.imlet.2012.03.007. Epub 2012 Mar 26.

PMID:
22469568
13.

Overexpression of GATA-3 in T cells accelerates dextran sulfate sodium-induced colitis.

Okamura M, Yoh K, Ojima M, Morito N, Takahashi S.

Exp Anim. 2014;63(2):133-40.

14.

Dextran sulfate sodium (DSS) induced experimental colitis in immunodeficient mice: effects in CD4(+) -cell depleted, athymic and NK-cell depleted SCID mice.

Axelsson LG, Landström E, Goldschmidt TJ, Grönberg A, Bylund-Fellenius AC.

Inflamm Res. 1996 Apr;45(4):181-91.

PMID:
8741008
15.

Interleukin‑21 promotes the development of ulcerative colitis and regulates the proliferation and secretion of follicular T helper cells in the colitides microenvironment.

Yu J, He S, Liu P, Hu Y, Wang L, Wang X, Han Y, Zhu X.

Mol Med Rep. 2015 Feb;11(2):1049-56. doi: 10.3892/mmr.2014.2824. Epub 2014 Oct 30.

PMID:
25371082
16.

Dysregulated upregulation of T-cell immunoglobulin and mucin domain-3 on mucosal T helper 1 cells in patients with Crohn's disease.

Morimoto K, Hosomi S, Yamagami H, Watanabe K, Kamata N, Sogawa M, Machida H, Okazaki H, Tanigawa T, Nagahara H, Noda E, Tominaga K, Watanabe T, Fujiwara Y, Maeda K, Hirakawa K, Arakawa T.

Scand J Gastroenterol. 2011 Jun;46(6):701-9. doi: 10.3109/00365521.2011.568518. Epub 2011 Apr 5.

PMID:
21463244
17.

Underexpression of TIM-3 and blunted galectin-9-induced apoptosis of CD4+ T cells in rheumatoid arthritis.

Lee J, Park EJ, Noh JW, Hwang JW, Bae EK, Ahn JK, Koh EM, Cha HS.

Inflammation. 2012 Apr;35(2):633-7. doi: 10.1007/s10753-011-9355-z.

PMID:
21717191
18.

3,3'-Diindolylmethane alleviates oxazolone-induced colitis through Th2/Th17 suppression and Treg induction.

Huang Z, Jiang Y, Yang Y, Shao J, Sun X, Chen J, Dong L, Zhang J.

Mol Immunol. 2013 Apr;53(4):335-44. doi: 10.1016/j.molimm.2012.09.007. Epub 2012 Oct 17.

PMID:
23085552
19.

TIM-3 and its regulatory role in immune responses.

Zhu C, Anderson AC, Kuchroo VK.

Curr Top Microbiol Immunol. 2011;350:1-15. doi: 10.1007/82_2010_84. Review.

PMID:
20700701
20.

Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis.

Seki M, Oomizu S, Sakata KM, Sakata A, Arikawa T, Watanabe K, Ito K, Takeshita K, Niki T, Saita N, Nishi N, Yamauchi A, Katoh S, Matsukawa A, Kuchroo V, Hirashima M.

Clin Immunol. 2008 Apr;127(1):78-88. doi: 10.1016/j.clim.2008.01.006. Epub 2008 Feb 20.

PMID:
18282810
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