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Items: 1 to 20 of 90

1.

Toward a biosynthetic route to sclareol and amber odorants.

Schalk M, Pastore L, Mirata MA, Khim S, Schouwey M, Deguerry F, Pineda V, Rocci L, Daviet L.

J Am Chem Soc. 2012 Nov 21;134(46):18900-3. doi: 10.1021/ja307404u. Epub 2012 Nov 7.

PMID:
23113661
2.

Discovery and functional characterization of two diterpene synthases for sclareol biosynthesis in Salvia sclarea (L.) and their relevance for perfume manufacture.

Caniard A, Zerbe P, Legrand S, Cohade A, Valot N, Magnard JL, Bohlmann J, Legendre L.

BMC Plant Biol. 2012 Jul 26;12:119. doi: 10.1186/1471-2229-12-119.

3.

Enzymes for synthetic biology of ambroxide-related diterpenoid fragrance compounds.

Zerbe P, Bohlmann J.

Adv Biochem Eng Biotechnol. 2015;148:427-47. doi: 10.1007/10_2015_308. Review.

PMID:
25846965
4.

Recent results in the search for new molecules with ambergris odor.

Panten J, Surburg H, Hölscher B.

Chem Biodivers. 2014 Oct;11(10):1639-50. doi: 10.1002/cbdv.201400153.

PMID:
25329789
5.

Iterative carotenogenic screens identify combinations of yeast gene deletions that enhance sclareol production.

Trikka FA, Nikolaidis A, Athanasakoglou A, Andreadelli A, Ignea C, Kotta K, Argiriou A, Kampranis SC, Makris AM.

Microb Cell Fact. 2015 Apr 24;14:60. doi: 10.1186/s12934-015-0246-0.

6.

Fragrance material review on sclareol.

Bhatia SP, McGinty D, Letizia CS, Api AM.

Food Chem Toxicol. 2008 Nov;46 Suppl 11:S270-4. doi: 10.1016/j.fct.2008.06.074. Epub 2008 Jul 2. Review.

PMID:
18640178
7.

Combinatorial QSAR of ambergris fragrance compounds.

Kovatcheva A, Golbraikh A, Oloff S, Xiao YD, Zheng W, Wolschann P, Buchbauer G, Tropsha A.

J Chem Inf Comput Sci. 2004 Mar-Apr;44(2):582-95.

PMID:
15032539
8.

Lower homologues of okoumal and disila-okoumal: synthesis and olfactory characterization of novel ambergris odorants.

Nätscher JB, Laskowski N, Kraft P, Tacke R.

Chembiochem. 2010 Feb 15;11(3):315-9. doi: 10.1002/cbic.200900680. No abstract available.

PMID:
20058254
9.

Extracellular localization of the diterpene sclareol in clary sage (Salvia sclarea L., Lamiaceae).

Caissard JC, Olivier T, Delbecque C, Palle S, Garry PP, Audran A, Valot N, Moja S, Nicolé F, Magnard JL, Legrand S, Baudino S, Jullien F.

PLoS One. 2012;7(10):e48253. doi: 10.1371/journal.pone.0048253. Epub 2012 Oct 25.

10.

The labdane diterpene sclareol (labd-14-ene-8, 13-diol) induces apoptosis in human tumor cell lines and suppression of tumor growth in vivo via a p53-independent mechanism of action.

Mahaira LG, Tsimplouli C, Sakellaridis N, Alevizopoulos K, Demetzos C, Han Z, Pantazis P, Dimas K.

Eur J Pharmacol. 2011 Sep;666(1-3):173-82. doi: 10.1016/j.ejphar.2011.04.065. Epub 2011 May 20.

PMID:
21620827
11.

Identification of four biliary metabolites of the diterpene sclareol in the laboratory rat.

Kouzi SA, McChesney JD, Walker LA.

Xenobiotica. 1993 Jun;23(6):621-32.

PMID:
8212736
12.

A comparative study of the effects of cholesterol and sclareol, a bioactive labdane type diterpene, on phospholipid bilayers.

Kyrikou I, Georgopoulos A, Hatziantoniou S, Mavromoustakos T, Demetzos C.

Chem Phys Lipids. 2005 Feb;133(2):125-34. Epub 2004 Nov 18.

PMID:
15642582
13.
14.

Effects of the diterpene sclareol glycol on body temperature in rats.

Georgieva J.

Methods Find Exp Clin Pharmacol. 1989 Apr;11(4):277-80.

PMID:
2755274
15.

Labd-14-ene-8,13-diol (sclareol) induces cell cycle arrest and apoptosis in human breast cancer cells and enhances the activity of anticancer drugs.

Dimas K, Papadaki M, Tsimplouli C, Hatziantoniou S, Alevizopoulos K, Pantazis P, Demetzos C.

Biomed Pharmacother. 2006 Apr;60(3):127-33. Epub 2006 Feb 21.

PMID:
16527443
16.

Chemical transformation and biological activities of ambrein, a major product of ambergris from Physeter macrocephalus (sperm whale).

Shen YC, Cheng SY, Kuo YH, Hwang TL, Chiang MY, Khalil AT.

J Nat Prod. 2007 Feb;70(2):147-53.

PMID:
17315955
17.

Biohydroxylation of (-)-ambrox®, (-)-sclareol, and (+)-sclareolide by whole cells of Brazilian marine-derived fungi.

Martins MP, Ouazzani J, Arcile G, Jeller AH, de Lima JP, Seleghim MH, Oliveira AL, Debonsi HM, Venâncio T, Yokoya NS, Fujii MT, Porto AL.

Mar Biotechnol (NY). 2015 Apr;17(2):211-8. doi: 10.1007/s10126-015-9610-7. Epub 2015 Jan 30.

PMID:
25634054
18.

Study of structural and electronic origin of ambergris odor of some compounds.

Cheng LP, Xu L, Mao HF, Wang GL.

J Mol Model. 2009 Jan;15(1):1-8. doi: 10.1007/s00894-008-0363-3. Epub 2008 Oct 21.

PMID:
18936989
19.
20.

Sclareol induces apoptosis in human HCT116 colon cancer cells in vitro and suppression of HCT116 tumor growth in immunodeficient mice.

Dimas K, Hatziantoniou S, Tseleni S, Khan H, Georgopoulos A, Alevizopoulos K, Wyche JH, Pantazis P, Demetzos C.

Apoptosis. 2007 Apr;12(4):685-94.

PMID:
17260186
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