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Results: 1 to 20 of 160

1.

The CARD plays a critical role in ASC foci formation and inflammasome signalling.

Proell M, Gerlic M, Mace PD, Reed JC, Riedl SJ.

Biochem J. 2013 Feb 1;449(3):613-21. doi: 10.1042/BJ20121198.

PMID:
23110696
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes.

Lu A, Magupalli VG, Ruan J, Yin Q, Atianand MK, Vos MR, Schröder GF, Fitzgerald KA, Wu H, Egelman EH.

Cell. 2014 Mar 13;156(6):1193-206. doi: 10.1016/j.cell.2014.02.008.

PMID:
24630722
[PubMed - indexed for MEDLINE]
3.

Novel role of PKR in inflammasome activation and HMGB1 release.

Lu B, Nakamura T, Inouye K, Li J, Tang Y, Lundbäck P, Valdes-Ferrer SI, Olofsson PS, Kalb T, Roth J, Zou Y, Erlandsson-Harris H, Yang H, Ting JP, Wang H, Andersson U, Antoine DJ, Chavan SS, Hotamisligil GS, Tracey KJ.

Nature. 2012 Aug 30;488(7413):670-4. doi: 10.1038/nature11290.

PMID:
22801494
[PubMed - indexed for MEDLINE]
4.

Salmonella infection induces recruitment of Caspase-8 to the inflammasome to modulate IL-1β production.

Man SM, Tourlomousis P, Hopkins L, Monie TP, Fitzgerald KA, Bryant CE.

J Immunol. 2013 Nov 15;191(10):5239-46. doi: 10.4049/jimmunol.1301581. Epub 2013 Oct 11.

PMID:
24123685
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Phosphorylation of NLRC4 is critical for inflammasome activation.

Qu Y, Misaghi S, Izrael-Tomasevic A, Newton K, Gilmour LL, Lamkanfi M, Louie S, Kayagaki N, Liu J, Kömüves L, Cupp JE, Arnott D, Monack D, Dixit VM.

Nature. 2012 Oct 25;490(7421):539-42. doi: 10.1038/nature11429. Epub 2012 Aug 12.

PMID:
22885697
[PubMed - indexed for MEDLINE]
6.

AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC.

Sagulenko V, Thygesen SJ, Sester DP, Idris A, Cridland JA, Vajjhala PR, Roberts TL, Schroder K, Vince JE, Hill JM, Silke J, Stacey KJ.

Cell Death Differ. 2013 Sep;20(9):1149-60. doi: 10.1038/cdd.2013.37. Epub 2013 May 3.

PMID:
23645208
[PubMed - indexed for MEDLINE]
7.

Asc modulates the function of NLRC4 in response to infection of macrophages by Legionella pneumophila.

Case CL, Roy CR.

MBio. 2011 Sep 1;2(4). pii: e00117-11. doi: 10.1128/mBio.00117-11. Print 2011.

PMID:
21771913
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Phosphorylation of the adaptor ASC acts as a molecular switch that controls the formation of speck-like aggregates and inflammasome activity.

Hara H, Tsuchiya K, Kawamura I, Fang R, Hernandez-Cuellar E, Shen Y, Mizuguchi J, Schweighoffer E, Tybulewicz V, Mitsuyama M.

Nat Immunol. 2013 Dec;14(12):1247-55. doi: 10.1038/ni.2749. Epub 2013 Nov 3.

PMID:
24185614
[PubMed - indexed for MEDLINE]
9.

Involvement of absent in melanoma 2 in inflammasome activation in macrophages infected with Listeria monocytogenes.

Tsuchiya K, Hara H, Kawamura I, Nomura T, Yamamoto T, Daim S, Dewamitta SR, Shen Y, Fang R, Mitsuyama M.

J Immunol. 2010 Jul 15;185(2):1186-95. doi: 10.4049/jimmunol.1001058. Epub 2010 Jun 21.

PMID:
20566831
[PubMed - indexed for MEDLINE]
Free Article
10.

Inflammasomes: guardians of cytosolic sanctity.

Lamkanfi M, Dixit VM.

Immunol Rev. 2009 Jan;227(1):95-105. doi: 10.1111/j.1600-065X.2008.00730.x. Review.

PMID:
19120479
[PubMed - indexed for MEDLINE]
11.

Regulatory molecules involved in inflammasome formation with special reference to a key mediator protein, ASC.

Taniguchi S, Sagara J.

Semin Immunopathol. 2007 Sep;29(3):231-8. Epub 2007 Sep 6. Review.

PMID:
17805543
[PubMed - indexed for MEDLINE]
12.

The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus.

Zhao Y, Yang J, Shi J, Gong YN, Lu Q, Xu H, Liu L, Shao F.

Nature. 2011 Sep 14;477(7366):596-600. doi: 10.1038/nature10510.

PMID:
21918512
[PubMed - indexed for MEDLINE]
13.

Apoptosis-associated speck-like protein containing a caspase recruitment domain is a regulator of procaspase-1 activation.

Stehlik C, Lee SH, Dorfleutner A, Stassinopoulos A, Sagara J, Reed JC.

J Immunol. 2003 Dec 1;171(11):6154-63.

PMID:
14634131
[PubMed - indexed for MEDLINE]
Free Article
14.

[Inflammatory bowel diseases and inflammasome].

Kim JM.

Korean J Gastroenterol. 2011 Dec;58(6):300-10. Review. Korean.

PMID:
22198227
[PubMed - indexed for MEDLINE]
Free Article
15.

Multiple binding sites on the pyrin domain of ASC protein allow self-association and interaction with NLRP3 protein.

Vajjhala PR, Mirams RE, Hill JM.

J Biol Chem. 2012 Dec 7;287(50):41732-43. doi: 10.1074/jbc.M112.381228. Epub 2012 Oct 12.

PMID:
23066025
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Critical roles of ASC inflammasomes in caspase-1 activation and host innate resistance to Streptococcus pneumoniae infection.

Fang R, Tsuchiya K, Kawamura I, Shen Y, Hara H, Sakai S, Yamamoto T, Fernandes-Alnemri T, Yang R, Hernandez-Cuellar E, Dewamitta SR, Xu Y, Qu H, Alnemri ES, Mitsuyama M.

J Immunol. 2011 Nov 1;187(9):4890-9. doi: 10.4049/jimmunol.1100381. Epub 2011 Sep 28.

PMID:
21957143
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Apoptosis-associated speck-like protein containing a caspase recruitment domain inflammasomes mediate IL-1β response and host resistance to Trypanosoma cruzi infection.

Silva GK, Costa RS, Silveira TN, Caetano BC, Horta CV, Gutierrez FR, Guedes PM, Andrade WA, De Niz M, Gazzinelli RT, Zamboni DS, Silva JS.

J Immunol. 2013 Sep 15;191(6):3373-83. doi: 10.4049/jimmunol.1203293. Epub 2013 Aug 21.

PMID:
23966627
[PubMed - indexed for MEDLINE]
18.

Promyelocytic leukemia protein interacts with the apoptosis-associated speck-like protein to limit inflammasome activation.

Dowling JK, Becker CE, Bourke NM, Corr SC, Connolly DJ, Quinn SR, Pandolfi PP, Mansell A, O'Neill LA.

J Biol Chem. 2014 Mar 7;289(10):6429-37. doi: 10.1074/jbc.M113.539692. Epub 2014 Jan 9.

PMID:
24407287
[PubMed - indexed for MEDLINE]
19.

Mechanisms of NOD-like receptor-associated inflammasome activation.

Wen H, Miao EA, Ting JP.

Immunity. 2013 Sep 19;39(3):432-41. doi: 10.1016/j.immuni.2013.08.037. Review.

PMID:
24054327
[PubMed - indexed for MEDLINE]
20.

Critical role of ASC inflammasomes and bacterial type IV secretion system in caspase-1 activation and host innate resistance to Brucella abortus infection.

Gomes MT, Campos PC, Oliveira FS, Corsetti PP, Bortoluci KR, Cunha LD, Zamboni DS, Oliveira SC.

J Immunol. 2013 Apr 1;190(7):3629-38. doi: 10.4049/jimmunol.1202817. Epub 2013 Mar 4.

PMID:
23460746
[PubMed - indexed for MEDLINE]
Free Article

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