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Items: 1 to 20 of 178


ER stress activates NF-κB by integrating functions of basal IKK activity, IRE1 and PERK.

Tam AB, Mercado EL, Hoffmann A, Niwa M.

PLoS One. 2012;7(10):e45078. doi: 10.1371/journal.pone.0045078. Epub 2012 Oct 26.


Selective, potent blockade of the IRE1 and ATF6 pathways by 4-phenylbutyric acid analogues.

Zhang H, Nakajima S, Kato H, Gu L, Yoshitomi T, Nagai K, Shinmori H, Kokubo S, Kitamura M.

Br J Pharmacol. 2013 Oct;170(4):822-34. doi: 10.1111/bph.12306.


PKR stimulates NF-kappaB irrespective of its kinase function by interacting with the IkappaB kinase complex.

Bonnet MC, Weil R, Dam E, Hovanessian AG, Meurs EF.

Mol Cell Biol. 2000 Jul;20(13):4532-42.


Plasma cell differentiation initiates a limited ER stress response by specifically suppressing the PERK-dependent branch of the unfolded protein response.

Ma Y, Shimizu Y, Mann MJ, Jin Y, Hendershot LM.

Cell Stress Chaperones. 2010 May;15(3):281-93. doi: 10.1007/s12192-009-0142-9. Epub 2009 Nov 8.


Signal transduction mechanisms involved in S100A4-induced activation of the transcription factor NF-kappaB.

Grotterød I, Maelandsmo GM, Boye K.

BMC Cancer. 2010 May 28;10:241. doi: 10.1186/1471-2407-10-241.


ER stress depresses NF-kappaB activation in mesangial cells through preferential induction of C/EBP beta.

Hayakawa K, Nakajima S, Hiramatsu N, Okamura M, Huang T, Saito Y, Tagawa Y, Tamai M, Takahashi S, Yao J, Kitamura M.

J Am Soc Nephrol. 2010 Jan;21(1):73-81. doi: 10.1681/ASN.2009040432. Epub 2009 Oct 29.


The catalytic activity of dsRNA-dependent protein kinase, PKR, is required for NF-kappaB activation.

Gil J, Rullas J, García MA, Alcamí J, Esteban M.

Oncogene. 2001 Jan 18;20(3):385-94.


Curcumin induces apoptotic cell death of activated human CD4+ T cells via increasing endoplasmic reticulum stress and mitochondrial dysfunction.

Zheng M, Zhang Q, Joe Y, Lee BH, Ryu do G, Kwon KB, Ryter SW, Chung HT.

Int Immunopharmacol. 2013 Mar;15(3):517-23. doi: 10.1016/j.intimp.2013.02.002. Epub 2013 Feb 15.


Genetic deletion of PKR abrogates TNF-induced activation of IkappaBalpha kinase, JNK, Akt and cell proliferation but potentiates p44/p42 MAPK and p38 MAPK activation.

Takada Y, Ichikawa H, Pataer A, Swisher S, Aggarwal BB.

Oncogene. 2007 Feb 22;26(8):1201-12. Epub 2006 Aug 21.


Endoplasmic reticulum stress sensing in the unfolded protein response.

Gardner BM, Pincus D, Gotthardt K, Gallagher CM, Walter P.

Cold Spring Harb Perspect Biol. 2013 Mar 1;5(3):a013169. doi: 10.1101/cshperspect.a013169. Review.


NF-kappaB dictates the degradation pathway of IkappaBalpha.

Mathes E, O'Dea EL, Hoffmann A, Ghosh G.

EMBO J. 2008 May 7;27(9):1357-67. doi: 10.1038/emboj.2008.73. Epub 2008 Apr 10. Erratum in: EMBO J. 2008 May 7;27(9):1421.


Prodigiosin activates endoplasmic reticulum stress cell death pathway in human breast carcinoma cell lines.

Pan MY, Shen YC, Lu CH, Yang SY, Ho TF, Peng YT, Chang CC.

Toxicol Appl Pharmacol. 2012 Dec 15;265(3):325-34. doi: 10.1016/j.taap.2012.08.034. Epub 2012 Sep 12.


PARP16 is a tail-anchored endoplasmic reticulum protein required for the PERK- and IRE1α-mediated unfolded protein response.

Jwa M, Chang P.

Nat Cell Biol. 2012 Nov;14(11):1223-30. doi: 10.1038/ncb2593. Epub 2012 Oct 28. Erratum in: Nat Cell Biol. 2013 Jan;15(1):123.


Endoplasmic reticulum stress-independent activation of unfolded protein response kinases by a small molecule ATP-mimic.

Mendez AS, Alfaro J, Morales-Soto MA, Dar AC, McCullagh E, Gotthardt K, Li H, Acosta-Alvear D, Sidrauski C, Korennykh AV, Bernales S, Shokat KM, Walter P.

Elife. 2015 May 19;4. doi: 10.7554/eLife.05434.

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