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Items: 1 to 20 of 101

1.

Identification of phosphorylation sites in the COOH-terminal tail of the μ-opioid receptor.

Chen YJ, Oldfield S, Butcher AJ, Tobin AB, Saxena K, Gurevich VV, Benovic JL, Henderson G, Kelly E.

J Neurochem. 2013 Jan;124(2):189-99. doi: 10.1111/jnc.12071. Epub 2012 Nov 30.

3.

Identification of two C-terminal amino acids, Ser(355) and Thr(357), required for short-term homologous desensitization of mu-opioid receptors.

Wang HL, Chang WT, Hsu CY, Huang PC, Chow YW, Li AH.

Biochem Pharmacol. 2002 Jul 15;64(2):257-66.

PMID:
12123746
4.

Phosphorylation of Ser363, Thr370, and Ser375 residues within the carboxyl tail differentially regulates mu-opioid receptor internalization.

El Kouhen R, Burd AL, Erickson-Herbrandson LJ, Chang CY, Law PY, Loh HH.

J Biol Chem. 2001 Apr 20;276(16):12774-80. Epub 2001 Jan 25.

5.

Role of G Protein-Coupled Receptor Kinases 2 and 3 in μ-Opioid Receptor Desensitization and Internalization.

Lowe JD, Sanderson HS, Cooke AE, Ostovar M, Tsisanova E, Withey SL, Chavkin C, Husbands SM, Kelly E, Henderson G, Bailey CP.

Mol Pharmacol. 2015 Aug;88(2):347-56. doi: 10.1124/mol.115.098293. Epub 2015 May 26.

6.

Agonist-selective mechanisms of mu-opioid receptor desensitization in human embryonic kidney 293 cells.

Johnson EA, Oldfield S, Braksator E, Gonzalez-Cuello A, Couch D, Hall KJ, Mundell SJ, Bailey CP, Kelly E, Henderson G.

Mol Pharmacol. 2006 Aug;70(2):676-85. Epub 2006 May 8.

8.

Protein kinase C-mediated phosphorylation of the μ-opioid receptor and its effects on receptor signaling.

Feng B, Li Z, Wang JB.

Mol Pharmacol. 2011 Apr;79(4):768-75. doi: 10.1124/mol.110.069096. Epub 2011 Jan 6.

9.

Deciphering µ-opioid receptor phosphorylation and dephosphorylation in HEK293 cells.

Doll C, Pöll F, Peuker K, Loktev A, Glück L, Schulz S.

Br J Pharmacol. 2012 Nov;167(6):1259-70. doi: 10.1111/j.1476-5381.2012.02080.x.

11.

A6V polymorphism of the human μ-opioid receptor decreases signalling of morphine and endogenous opioids in vitro.

Knapman A, Santiago M, Connor M.

Br J Pharmacol. 2015 May;172(9):2258-72. doi: 10.1111/bph.13047. Epub 2015 Mar 17.

12.

Role of Phosphorylation Sites in Desensitization of µ-Opioid Receptor.

Yousuf A, Miess E, Sianati S, Du YP, Schulz S, Christie MJ.

Mol Pharmacol. 2015 Oct;88(4):825-35. doi: 10.1124/mol.115.098244. Epub 2015 May 12.

PMID:
25969388
13.

Endomorphin-2: a biased agonist at the μ-opioid receptor.

Rivero G, Llorente J, McPherson J, Cooke A, Mundell SJ, McArdle CA, Rosethorne EM, Charlton SJ, Krasel C, Bailey CP, Henderson G, Kelly E.

Mol Pharmacol. 2012 Aug;82(2):178-88. doi: 10.1124/mol.112.078659. Epub 2012 May 2.

14.

Agonist Binding and Desensitization of the μ-Opioid Receptor Is Modulated by Phosphorylation of the C-Terminal Tail Domain.

Birdsong WT, Arttamangkul S, Bunzow JR, Williams JT.

Mol Pharmacol. 2015 Oct;88(4):816-24. doi: 10.1124/mol.114.097527. Epub 2015 May 1.

PMID:
25934731
15.

μ-opioid receptors: correlation of agonist efficacy for signalling with ability to activate internalization.

McPherson J, Rivero G, Baptist M, Llorente J, Al-Sabah S, Krasel C, Dewey WL, Bailey CP, Rosethorne EM, Charlton SJ, Henderson G, Kelly E.

Mol Pharmacol. 2010 Oct;78(4):756-66. doi: 10.1124/mol.110.066613. Epub 2010 Jul 20.

16.

Orphanin FQ/nociceptin potentiates [D-Ala2,N-Me-Phe4,Gly5-ol]-enkephalin-Induced mu-opioid receptor phosphorylation.

Ozsoy HZ, Thakker DR, Standifer KM.

Mol Pharmacol. 2005 Aug;68(2):447-56. Epub 2005 May 12.

18.

μ-Opioid receptor desensitization: homologous or heterologous?

Llorente J, Lowe JD, Sanderson HS, Tsisanova E, Kelly E, Henderson G, Bailey CP.

Eur J Neurosci. 2012 Dec;36(12):3636-42. doi: 10.1111/ejn.12003. Epub 2012 Sep 24.

19.

Phosphorylation and agonist-specific intracellular trafficking of an epitope-tagged mu-opioid receptor expressed in HEK 293 cells.

Arden JR, Segredo V, Wang Z, Lameh J, Sadée W.

J Neurochem. 1995 Oct;65(4):1636-45.

PMID:
7561859
20.
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