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Results: 1 to 20 of 154

1.

G9a/GLP-dependent histone H3K9me2 patterning during human hematopoietic stem cell lineage commitment.

Chen X, Skutt-Kakaria K, Davison J, Ou YL, Choi E, Malik P, Loeb K, Wood B, Georges G, Torok-Storb B, Paddison PJ.

Genes Dev. 2012 Nov 15;26(22):2499-511. doi: 10.1101/gad.200329.112. Epub 2012 Oct 26.

PMID:
23105005
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

G9a/GLP-dependent H3K9me2 patterning alters chromatin structure at CpG islands in hematopoietic progenitors.

Schones DE, Chen X, Trac C, Setten R, Paddison PJ.

Epigenetics Chromatin. 2014 Sep 10;7:23. doi: 10.1186/1756-8935-7-23. eCollection 2014.

PMID:
25237399
[PubMed]
3.

A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells.

Vedadi M, Barsyte-Lovejoy D, Liu F, Rival-Gervier S, Allali-Hassani A, Labrie V, Wigle TJ, Dimaggio PA, Wasney GA, Siarheyeva A, Dong A, Tempel W, Wang SC, Chen X, Chau I, Mangano TJ, Huang XP, Simpson CD, Pattenden SG, Norris JL, Kireev DB, Tripathy A, Edwards A, Roth BL, Janzen WP, Garcia BA, Petronis A, Ellis J, Brown PJ, Frye SV, Arrowsmith CH, Jin J.

Nat Chem Biol. 2011 Jul 10;7(8):566-74. doi: 10.1038/nchembio.599. Erratum in: Nat Chem Biol. 2011 Sep;7(9):648. Nat Chem Biol. 2011;7(8):following 574.

PMID:
21743462
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Distinct roles for histone methyltransferases G9a and GLP in cancer germ-line antigen gene regulation in human cancer cells and murine embryonic stem cells.

Link PA, Gangisetty O, James SR, Woloszynska-Read A, Tachibana M, Shinkai Y, Karpf AR.

Mol Cancer Res. 2009 Jun;7(6):851-62. doi: 10.1158/1541-7786.MCR-08-0497. Epub 2009 Jun 16.

PMID:
19531572
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

G9a/GLP histone lysine dimethyltransferase complex activity in the hippocampus and the entorhinal cortex is required for gene activation and silencing during memory consolidation.

Gupta-Agarwal S, Franklin AV, Deramus T, Wheelock M, Davis RL, McMahon LL, Lubin FD.

J Neurosci. 2012 Apr 18;32(16):5440-53. doi: 10.1523/JNEUROSCI.0147-12.2012.

PMID:
22514307
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase.

Kubicek S, O'Sullivan RJ, August EM, Hickey ER, Zhang Q, Teodoro ML, Rea S, Mechtler K, Kowalski JA, Homon CA, Kelly TA, Jenuwein T.

Mol Cell. 2007 Feb 9;25(3):473-81.

PMID:
17289593
[PubMed - indexed for MEDLINE]
Free Article
7.

H3K9 methyltransferase G9a and the related molecule GLP.

Shinkai Y, Tachibana M.

Genes Dev. 2011 Apr 15;25(8):781-8. doi: 10.1101/gad.2027411. Review.

PMID:
21498567
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Activating and inhibitory functions for the histone lysine methyltransferase G9a in T helper cell differentiation and function.

Lehnertz B, Northrop JP, Antignano F, Burrows K, Hadidi S, Mullaly SC, Rossi FM, Zaph C.

J Exp Med. 2010 May 10;207(5):915-22. doi: 10.1084/jem.20100363. Epub 2010 Apr 26.

PMID:
20421388
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9.

Tachibana M, Ueda J, Fukuda M, Takeda N, Ohta T, Iwanari H, Sakihama T, Kodama T, Hamakubo T, Shinkai Y.

Genes Dev. 2005 Apr 1;19(7):815-26. Epub 2005 Mar 17.

PMID:
15774718
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Hypoxic stress induces dimethylated histone H3 lysine 9 through histone methyltransferase G9a in mammalian cells.

Chen H, Yan Y, Davidson TL, Shinkai Y, Costa M.

Cancer Res. 2006 Sep 15;66(18):9009-16.

PMID:
16982742
[PubMed - indexed for MEDLINE]
Free Article
11.

G9a/GLP complexes independently mediate H3K9 and DNA methylation to silence transcription.

Tachibana M, Matsumura Y, Fukuda M, Kimura H, Shinkai Y.

EMBO J. 2008 Oct 22;27(20):2681-90. doi: 10.1038/emboj.2008.192. Epub 2008 Sep 25.

PMID:
18818694
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

The MSX1 homeoprotein recruits G9a methyltransferase to repressed target genes in myoblast cells.

Wang J, Abate-Shen C.

PLoS One. 2012;7(5):e37647. doi: 10.1371/journal.pone.0037647. Epub 2012 May 22.

PMID:
22629437
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Histone H3 lysine 9 methyltransferases, G9a and GLP are essential for cardiac morphogenesis.

Inagawa M, Nakajima K, Makino T, Ogawa S, Kojima M, Ito S, Ikenishi A, Hayashi T, Schwartz RJ, Nakamura K, Obayashi T, Tachibana M, Shinkai Y, Maeda K, Miyagawa-Tomita S, Takeuchi T.

Mech Dev. 2013 Nov-Dec;130(11-12):519-31. doi: 10.1016/j.mod.2013.07.002. Epub 2013 Jul 24.

PMID:
23892084
[PubMed - indexed for MEDLINE]
14.

Gfi1 coordinates epigenetic repression of p21Cip/WAF1 by recruitment of histone lysine methyltransferase G9a and histone deacetylase 1.

Duan Z, Zarebski A, Montoya-Durango D, Grimes HL, Horwitz M.

Mol Cell Biol. 2005 Dec;25(23):10338-51.

PMID:
16287849
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Inhibition of H3K9 methyltransferases G9a/GLP prevents ototoxicity and ongoing hair cell death.

Yu H, Lin Q, Wang Y, He Y, Fu S, Jiang H, Yu Y, Sun S, Chen Y, Shou J, Li H.

Cell Death Dis. 2013 Feb 21;4:e506. doi: 10.1038/cddis.2013.28.

PMID:
23429292
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Methyltransferase G9A regulates T cell differentiation during murine intestinal inflammation.

Antignano F, Burrows K, Hughes MR, Han JM, Kron KJ, Penrod NM, Oudhoff MJ, Wang SK, Min PH, Gold MJ, Chenery AL, Braam MJ, Fung TC, Rossi FM, McNagny KM, Arrowsmith CH, Lupien M, Levings MK, Zaph C.

J Clin Invest. 2014 May 1;124(5):1945-55. doi: 10.1172/JCI69592. Epub 2014 Mar 25.

PMID:
24667637
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

A subset of the histone H3 lysine 9 methyltransferases Suv39h1, G9a, GLP, and SETDB1 participate in a multimeric complex.

Fritsch L, Robin P, Mathieu JR, Souidi M, Hinaux H, Rougeulle C, Harel-Bellan A, Ameyar-Zazoua M, Ait-Si-Ali S.

Mol Cell. 2010 Jan 15;37(1):46-56. doi: 10.1016/j.molcel.2009.12.017.

PMID:
20129054
[PubMed - indexed for MEDLINE]
Free Article
18.

Involvement of histone H3 lysine 9 (H3K9) methyltransferase G9a in the maintenance of HIV-1 latency and its reactivation by BIX01294.

Imai K, Togami H, Okamoto T.

J Biol Chem. 2010 May 28;285(22):16538-45. doi: 10.1074/jbc.M110.103531. Epub 2010 Mar 24.

PMID:
20335163
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

LSH and G9a/GLP complex are required for developmentally programmed DNA methylation.

Myant K, Termanis A, Sundaram AY, Boe T, Li C, Merusi C, Burrage J, de Las Heras JI, Stancheva I.

Genome Res. 2011 Jan;21(1):83-94. doi: 10.1101/gr.108498.110. Epub 2010 Dec 13.

PMID:
21149390
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Posttranscriptional regulation of histone lysine methyltransferase GLP in embryonic male mouse germ cells.

Deguchi K, Nagamatsu G, Miyachi H, Kato Y, Morita S, Kimura H, Kitano S, Hatada I, Saga Y, Tachibana M, Shinkai Y.

Biol Reprod. 2013 Feb 14;88(2):36. doi: 10.1095/biolreprod.112.103572. Print 2013 Feb.

PMID:
23284137
[PubMed - indexed for MEDLINE]
Free Article

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