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Related Citations for PubMed (Select 23103865)


The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity.

Nandakumar J, Bell CF, Weidenfeld I, Zaug AJ, Leinwand LA, Cech TR.

Nature. 2012 Dec 13;492(7428):285-9. doi: 10.1038/nature11648. Epub 2012 Oct 24.


TPP1 is a homologue of ciliate TEBP-beta and interacts with POT1 to recruit telomerase.

Xin H, Liu D, Wan M, Safari A, Kim H, Sun W, O'Connor MS, Songyang Z.

Nature. 2007 Feb 1;445(7127):559-62. Epub 2007 Jan 21.


The POT1-TPP1 telomere complex is a telomerase processivity factor.

Wang F, Podell ER, Zaug AJ, Yang Y, Baciu P, Cech TR, Lei M.

Nature. 2007 Feb 1;445(7127):506-10. Epub 2007 Jan 21.


Functional interaction between telomere protein TPP1 and telomerase.

Zaug AJ, Podell ER, Nandakumar J, Cech TR.

Genes Dev. 2010 Mar 15;24(6):613-22. doi: 10.1101/gad.1881810.


Specificity requirements for human telomere protein interaction with telomerase holoenzyme.

Sexton AN, Youmans DT, Collins K.

J Biol Chem. 2012 Oct 5;287(41):34455-64. doi: 10.1074/jbc.M112.394767. Epub 2012 Aug 14.


TIN2-tethered TPP1 recruits human telomerase to telomeres in vivo.

Abreu E, Aritonovska E, Reichenbach P, Cristofari G, Culp B, Terns RM, Lingner J, Terns MP.

Mol Cell Biol. 2010 Jun;30(12):2971-82. doi: 10.1128/MCB.00240-10. Epub 2010 Apr 19.


TPP1 OB-fold domain controls telomere maintenance by recruiting telomerase to chromosome ends.

Zhong FL, Batista LF, Freund A, Pech MF, Venteicher AS, Artandi SE.

Cell. 2012 Aug 3;150(3):481-94. doi: 10.1016/j.cell.2012.07.012.


In vivo stoichiometry of shelterin components.

Takai KK, Hooper S, Blackwood S, Gandhi R, de Lange T.

J Biol Chem. 2010 Jan 8;285(2):1457-67. doi: 10.1074/jbc.M109.038026. Epub 2009 Oct 28.


Human telomere POT1-TPP1 complex and its role in telomerase activity regulation.

Wang F, Lei M.

Methods Mol Biol. 2011;735:173-87. doi: 10.1007/978-1-61779-092-8_17.


POT1-TPP1 enhances telomerase processivity by slowing primer dissociation and aiding translocation.

Latrick CM, Cech TR.

EMBO J. 2010 Mar 3;29(5):924-33. doi: 10.1038/emboj.2009.409. Epub 2010 Jan 21.


The shelterin component TPP1 is a binding partner and substrate for the deubiquitinating enzyme USP7.

Zemp I, Lingner J.

J Biol Chem. 2014 Oct 10;289(41):28595-606. doi: 10.1074/jbc.M114.596056. Epub 2014 Aug 29.


The human CST complex is a terminator of telomerase activity.

Chen LY, Redon S, Lingner J.

Nature. 2012 Aug 23;488(7412):540-4. doi: 10.1038/nature11269.


Fission yeast Pot1-Tpp1 protects telomeres and regulates telomere length.

Miyoshi T, Kanoh J, Saito M, Ishikawa F.

Science. 2008 Jun 6;320(5881):1341-4. doi: 10.1126/science.1154819.


Hoyeraal-Hreidarsson syndrome caused by a germline mutation in the TEL patch of the telomere protein TPP1.

Kocak H, Ballew BJ, Bisht K, Eggebeen R, Hicks BD, Suman S, O'Neil A, Giri N; NCI DCEG Cancer Genomics Research Laboratory; NCI DCEG Cancer Sequencing Working Group, Maillard I, Alter BP, Keegan CE, Nandakumar J, Savage SA.

Genes Dev. 2014 Oct 1;28(19):2090-102. doi: 10.1101/gad.248567.114. Epub 2014 Sep 18.


Genetic and molecular identification of three human TPP1 functions in telomerase action: recruitment, activation, and homeostasis set point regulation.

Sexton AN, Regalado SG, Lai CS, Cost GJ, O'Neil CM, Urnov FD, Gregory PD, Jaenisch R, Collins K, Hockemeyer D.

Genes Dev. 2014 Sep 1;28(17):1885-99. doi: 10.1101/gad.246819.114. Epub 2014 Aug 15.


Telomere protection by mammalian Pot1 requires interaction with Tpp1.

Hockemeyer D, Palm W, Else T, Daniels JP, Takai KK, Ye JZ, Keegan CE, de Lange T, Hammer GD.

Nat Struct Mol Biol. 2007 Aug;14(8):754-61. Epub 2007 Jul 15. Erratum in: Nat Struct Mol Biol. 2009 May;16(5):572.


Coordinated interactions of multiple POT1-TPP1 proteins with telomere DNA.

Corriveau M, Mullins MR, Baus D, Harris ME, Taylor DJ.

J Biol Chem. 2013 Jun 7;288(23):16361-70. doi: 10.1074/jbc.M113.471896. Epub 2013 Apr 24.


Distinct functions of POT1 at telomeres.

Barrientos KS, Kendellen MF, Freibaum BD, Armbruster BN, Etheridge KT, Counter CM.

Mol Cell Biol. 2008 Sep;28(17):5251-64. doi: 10.1128/MCB.00048-08. Epub 2008 Jun 2.


Shelterin: the protein complex that shapes and safeguards human telomeres.

de Lange T.

Genes Dev. 2005 Sep 15;19(18):2100-10. Review.

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