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Results: 1 to 20 of 106

1.

Impact of common genetic variation on response to simvastatin therapy among 18 705 participants in the Heart Protection Study.

Hopewell JC, Parish S, Offer A, Link E, Clarke R, Lathrop M, Armitage J, Collins R; MRC/BHF Heart Protection Study Collaborative Group.

Eur Heart J. 2013 Apr;34(13):982-92. doi: 10.1093/eurheartj/ehs344. Epub 2012 Oct 24.

PMID:
23100282
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Impact of variants within seven candidate genes on statin treatment efficacy.

Vrablík M, Hubáček JA, Dlouhá D, Lánská V, Rynekrová J, Zlatohlávek L, Prusíková M, Ceška R, Adámková V.

Physiol Res. 2012;61(6):609-17. Epub 2012 Oct 25.

PMID:
23098650
[PubMed - indexed for MEDLINE]
Free Article
3.

Genes and cardiovascular risk.

Faergeman O.

Eur Heart J. 2013 Apr;34(13):949-50. doi: 10.1093/eurheartj/ehs439. Epub 2012 Dec 19. No abstract available.

PMID:
23257949
[PubMed - indexed for MEDLINE]
Free Article
4.

Genetic determinants of statin-induced low-density lipoprotein cholesterol reduction: the Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER) trial.

Chasman DI, Giulianini F, MacFadyen J, Barratt BJ, Nyberg F, Ridker PM.

Circ Cardiovasc Genet. 2012 Apr 1;5(2):257-64. doi: 10.1161/CIRCGENETICS.111.961144. Epub 2012 Feb 13. Erratum in: Circ Cardiovasc Genet. 2012 Jun;5(3):e27.

PMID:
22331829
[PubMed - indexed for MEDLINE]
Free Article
5.

Genetic loci associated with plasma concentration of low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglycerides, apolipoprotein A1, and Apolipoprotein B among 6382 white women in genome-wide analysis with replication.

Chasman DI, Paré G, Zee RY, Parker AN, Cook NR, Buring JE, Kwiatkowski DJ, Rose LM, Smith JD, Williams PT, Rieder MJ, Rotter JI, Nickerson DA, Krauss RM, Miletich JP, Ridker PM.

Circ Cardiovasc Genet. 2008 Oct;1(1):21-30. doi: 10.1161/CIRCGENETICS.108.773168.

PMID:
19802338
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial.

Heart Protection Study Collaborative Group.

Lancet. 2002 Jul 6;360(9326):7-22.

PMID:
12114036
[PubMed - indexed for MEDLINE]
7.

The efficacy and safety of ezetimibe/simvastatin combination compared with intensified lipid-lowering treatment strategies in diabetic subjects with and without metabolic syndrome.

Jimenez JG, Rosen JB, Pirags V, Massaad R, Hanson ME, Brudi P, Triscari J.

Diabetes Obes Metab. 2013 Jun;15(6):513-22. doi: 10.1111/dom.12059. Epub 2013 Jan 25.

PMID:
23279632
[PubMed - indexed for MEDLINE]
8.

Consistency in efficacy and safety of ezetimibe coadministered with statins for treatment of hypercholesterolemia in women and men.

Bennett S, Sager P, Lipka L, Melani L, Suresh R, Veltri E; Ezetimibe Study Group.

J Womens Health (Larchmt). 2004 Dec;13(10):1101-7.

PMID:
15650343
[PubMed - indexed for MEDLINE]
9.

Achievement of specified low-density lipoprotein cholesterol, non-high-density lipoprotein cholesterol apolipoprotein B, and high-sensitivity C-reactive protein levels with ezetimibe/simvastatin or atorvastatin in metabolic syndrome patients with and without atherosclerotic vascular disease (from the VYMET study).

Robinson JG, Ballantyne CM, Hsueh W, Rosen J, Lin J, Shah A, Lowe RS, Hanson ME, Tershakovec AM.

J Clin Lipidol. 2011 Nov-Dec;5(6):474-82. doi: 10.1016/j.jacl.2011.06.004. Epub 2011 Jun 15.

PMID:
22108151
[PubMed - indexed for MEDLINE]
10.

Phenotypic predictors of response to simvastatin therapy among African-Americans and Caucasians: the Cholesterol and Pharmacogenetics (CAP) Study.

Simon JA, Lin F, Hulley SB, Blanche PJ, Waters D, Shiboski S, Rotter JI, Nickerson DA, Yang H, Saad M, Krauss RM.

Am J Cardiol. 2006 Mar 15;97(6):843-50. Epub 2006 Jan 27.

PMID:
16516587
[PubMed - indexed for MEDLINE]
11.

Targeting low HDL-cholesterol to decrease residual cardiovascular risk in the managed care setting.

Cziraky MJ, Watson KE, Talbert RL.

J Manag Care Pharm. 2008 Oct;14(8 Suppl):S3-28; quiz S30-1. Review.

PMID:
19891279
[PubMed - indexed for MEDLINE]
Free Article
12.

Effects of ezetimibe, simvastatin and ezetimibe/simvastatin on correlations between apolipoprotein B, LDL cholesterol and non-HDL cholesterol in patients with primary hypercholesterolemia.

Farnier M, Guyton JR, Jensen E, Polis AB, Johnson-Levonas AO, Brudi P.

Atherosclerosis. 2013 Aug;229(2):415-22. doi: 10.1016/j.atherosclerosis.2013.05.010. Epub 2013 Jun 5.

PMID:
23880197
[PubMed - indexed for MEDLINE]
13.

Association of LDL cholesterol, non-HDL cholesterol, and apolipoprotein B levels with risk of cardiovascular events among patients treated with statins: a meta-analysis.

Boekholdt SM, Arsenault BJ, Mora S, Pedersen TR, LaRosa JC, Nestel PJ, Simes RJ, Durrington P, Hitman GA, Welch KM, DeMicco DA, Zwinderman AH, Clearfield MB, Downs JR, Tonkin AM, Colhoun HM, Gotto AM Jr, Ridker PM, Kastelein JJ.

JAMA. 2012 Mar 28;307(12):1302-9. doi: 10.1001/jama.2012.366. Erratum in: JAMA. 2012 Apr 25;307(16):1694. JAMA. 2012 May 9;307(18):1915.

PMID:
22453571
[PubMed - indexed for MEDLINE]
14.

Intronic variants in SLCO1B1 related to statin-induced myopathy are associated with the low-density lipoprotein cholesterol response to statins in Chinese patients with hyperlipidaemia.

Hu M, Mak VW, Tomlinson B.

Pharmacogenet Genomics. 2012 Nov;22(11):803-6. doi: 10.1097/FPC.0b013e3283557c98.

PMID:
22668755
[PubMed - indexed for MEDLINE]
15.

A 52-week, multicenter, randomized, parallel-group, double-blind, double-dummy study to assess the efficacy of atorvastatin and simvastatin in reaching low-density lipoprotein cholesterol and triglyceride targets: the treat-to-target (3T) study.

Olsson AG, Eriksson M, Johnson O, Kjellström T, Lanke J, Larsen ML, Pedersen T, Tikkanen MJ, Wiklund O; 3T Study Investigators.

Clin Ther. 2003 Jan;25(1):119-38.

PMID:
12637115
[PubMed - indexed for MEDLINE]
16.

Efficacy and safety of a new cholesterol synthesis inhibitor, atorvastatin, in comparison with simvastatin and pravastatin, in subjects with hypercholesterolemia.

Wolffenbuttel BH, Mahla G, Muller D, Pentrup A, Black DM.

Neth J Med. 1998 Apr;52(4):131-7.

PMID:
9646621
[PubMed - indexed for MEDLINE]
17.

Effects of rosuvastatin versus atorvastatin, simvastatin, and pravastatin on non-high-density lipoprotein cholesterol, apolipoproteins, and lipid ratios in patients with hypercholesterolemia: additional results from the STELLAR trial.

Jones PH, Hunninghake DB, Ferdinand KC, Stein EA, Gold A, Caplan RJ, Blasetto JW; Statin Therapies for Elevated Lipid Levels Compared Across Doses to Rosuvastatin Study Group.

Clin Ther. 2004 Sep;26(9):1388-99. Erratum in: Clin Ther. 2005 Jan;27(1):142.

PMID:
15531001
[PubMed - indexed for MEDLINE]
18.

KIF6, LPA, TAS2R50, and VAMP8 genetic variation, low density lipoprotein cholesterol lowering response to pravastatin, and heart disease risk reduction in the elderly.

Akao H, Polisecki E, Kajinami K, Trompet S, Robertson M, Ford I, Jukema JW, de Craen AJ, Westendorp RG, Shepherd J, Packard C, Buckley BM, Schaefer EJ.

Atherosclerosis. 2012 Feb;220(2):456-62. doi: 10.1016/j.atherosclerosis.2011.11.037. Epub 2011 Dec 7.

PMID:
22192511
[PubMed - indexed for MEDLINE]
19.

Efficacy and safety of rosuvastatin and fenofibric acid combination therapy versus simvastatin monotherapy in patients with hypercholesterolemia and hypertriglyceridemia: a randomized, double-blind study.

Roth EM, McKenney JM, Kelly MT, Setze CM, Carlson DM, Gold A, Stolzenbach JC, Williams LA, Jones PH.

Am J Cardiovasc Drugs. 2010;10(3):175-86. doi: 10.2165/11533430-000000000-00000.

PMID:
20524719
[PubMed - indexed for MEDLINE]
20.

Pharmacogenetic determinants of statin-induced reductions in C-reactive protein.

Chu AY, Guilianini F, Barratt BJ, Nyberg F, Chasman DI, Ridker PM.

Circ Cardiovasc Genet. 2012 Feb 1;5(1):58-65. doi: 10.1161/CIRCGENETICS.111.961847. Epub 2012 Jan 9.

PMID:
22230323
[PubMed - indexed for MEDLINE]
Free Article

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