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Results: 1 to 20 of 121

1.

The role of dimethylarginine dimethylaminohydrolase (DDAH) in pulmonary fibrosis.

Janssen W, Pullamsetti SS, Cooke J, Weissmann N, Guenther A, Schermuly RT.

J Pathol. 2013 Jan;229(2):242-9. doi: 10.1002/path.4127. Review.

PMID:
23097221
[PubMed - indexed for MEDLINE]
2.

The role of dimethylarginine dimethylaminohydrolase in idiopathic pulmonary fibrosis.

Pullamsetti SS, Savai R, Dumitrascu R, Dahal BK, Wilhelm J, Konigshoff M, Zakrzewicz D, Ghofrani HA, Weissmann N, Eickelberg O, Guenther A, Leiper J, Seeger W, Grimminger F, Schermuly RT.

Sci Transl Med. 2011 Jun 15;3(87):87ra53. doi: 10.1126/scitranslmed.3001725.

PMID:
21677199
[PubMed - indexed for MEDLINE]
Free Article
3.

S-nitrosylation of dimethylarginine dimethylaminohydrolase regulates enzyme activity: further interactions between nitric oxide synthase and dimethylarginine dimethylaminohydrolase.

Leiper J, Murray-Rust J, McDonald N, Vallance P.

Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13527-32. Epub 2002 Oct 7.

PMID:
12370443
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Gene transfer of dimethylarginine dimethylaminohydrolase-2 improves the impairments of DDAH/ADMA/NOS/NO pathway in endothelial cells induced by lysophosphatidylcholine.

Feng M, Liu L, Guo Z, Xiong Y.

Eur J Pharmacol. 2008 Apr 14;584(1):49-56. doi: 10.1016/j.ejphar.2008.01.029. Epub 2008 Feb 5.

PMID:
18342305
[PubMed - indexed for MEDLINE]
5.

Regulation of cytokine-induced nitric oxide synthesis by asymmetric dimethylarginine: role of dimethylarginine dimethylaminohydrolase.

Ueda S, Kato S, Matsuoka H, Kimoto M, Okuda S, Morimatsu M, Imaizumi T.

Circ Res. 2003 Feb 7;92(2):226-33.

PMID:
12574151
[PubMed - indexed for MEDLINE]
Free Article
6.

Evidence for dysregulation of dimethylarginine dimethylaminohydrolase I in chronic hypoxia-induced pulmonary hypertension.

Millatt LJ, Whitley GS, Li D, Leiper JM, Siragy HM, Carey RM, Johns RA.

Circulation. 2003 Sep 23;108(12):1493-8. Epub 2003 Sep 2.

PMID:
12952847
[PubMed - indexed for MEDLINE]
Free Article
7.

Mechanisms of nitric oxide synthase uncoupling in endotoxin-induced acute lung injury: role of asymmetric dimethylarginine.

Sharma S, Smith A, Kumar S, Aggarwal S, Rehmani I, Snead C, Harmon C, Fineman J, Fulton D, Catravas JD, Black SM.

Vascul Pharmacol. 2010 May-Jun;52(5-6):182-90. doi: 10.1016/j.vph.2009.11.010. Epub 2009 Dec 3.

PMID:
19962451
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Human recombinant erythropoietin augments serum asymmetric dimethylarginine concentrations but does not compromise nitric oxide generation in mice.

Desai A, Zhao Y, Warren JS.

Nephrol Dial Transplant. 2008 May;23(5):1513-20. doi: 10.1093/ndt/gfm869. Epub 2008 Jan 19.

PMID:
18204093
[PubMed - indexed for MEDLINE]
Free Article
9.

Nitric oxide upregulates dimethylarginine dimethylaminohydrolase-2 via cyclic GMP induction in endothelial cells.

Sakurada M, Shichiri M, Imamura M, Azuma H, Hirata Y.

Hypertension. 2008 Nov;52(5):903-9. doi: 10.1161/HYPERTENSIONAHA.108.114207. Epub 2008 Sep 29.

PMID:
18824664
[PubMed - indexed for MEDLINE]
Free Article
10.

Homocysteine increases the production of asymmetric dimethylarginine in cultured neurons.

Selley ML.

J Neurosci Res. 2004 Jul 1;77(1):90-3.

PMID:
15197741
[PubMed - indexed for MEDLINE]
11.
12.

Dimethylarginine dimethylaminohydrolase regulation: a novel therapeutic target in cardiovascular disease.

Wadham C, Mangoni AA.

Expert Opin Drug Metab Toxicol. 2009 Mar;5(3):303-19. doi: 10.1517/17425250902785172 . Review.

PMID:
19331593
[PubMed - indexed for MEDLINE]
13.

The DDAH/ADMA/NOS pathway.

Tran CT, Leiper JM, Vallance P.

Atheroscler Suppl. 2003 Dec;4(4):33-40. Review.

PMID:
14664901
[PubMed - indexed for MEDLINE]
14.

Roles of accumulated endogenous nitric oxide synthase inhibitors, enhanced arginase activity, and attenuated nitric oxide synthase activity in endothelial cells for pulmonary hypertension in rats.

Sasaki A, Doi S, Mizutani S, Azuma H.

Am J Physiol Lung Cell Mol Physiol. 2007 Jun;292(6):L1480-7. Epub 2007 Feb 23.

PMID:
17322279
[PubMed - indexed for MEDLINE]
Free Article
15.

all-trans-Retinoic acid increases nitric oxide synthesis by endothelial cells: a role for the induction of dimethylarginine dimethylaminohydrolase.

Achan V, Tran CT, Arrigoni F, Whitley GS, Leiper JM, Vallance P.

Circ Res. 2002 Apr 19;90(7):764-9.

PMID:
11964368
[PubMed - indexed for MEDLINE]
Free Article
16.

Asymmetric dimethyl L-arginine (ADMA) is a critical regulator of myocardial reperfusion injury.

Stühlinger MC, Conci E, Haubner BJ, Stocker EM, Schwaighofer J, Cooke JP, Tsao PS, Pachinger O, Metzler B.

Cardiovasc Res. 2007 Jul 15;75(2):417-25. Epub 2007 May 5.

PMID:
17559823
[PubMed - indexed for MEDLINE]
Free Article
17.

Dimethylarginine dimethylaminohydrolase 1 regulates nerve growth factor-promoted differentiation of PC12 cells in a nitric oxide-dependent but asymmetric dimethylargenine-independent manner.

Wang S, Hu CP, Yuan Q, Zhang WF, Zhou Z, Nie SD, Jiang JL, Li YJ.

J Neurosci Res. 2012 Jun;90(6):1209-17. doi: 10.1002/jnr.23009. Epub 2012 Feb 20.

PMID:
22488726
[PubMed - indexed for MEDLINE]
18.

Structure-activity relationship of novel and known inhibitors of human dimethylarginine dimethylaminohydrolase-1: alkenyl-amidines as new leads.

Kotthaus J, Schade D, Muschick N, Beitz E, Clement B.

Bioorg Med Chem. 2008 Dec 15;16(24):10205-9. doi: 10.1016/j.bmc.2008.10.058. Epub 2008 Oct 29.

PMID:
19013076
[PubMed - indexed for MEDLINE]
19.

GC-MS assay for hepatic DDAH activity in diabetic and non-diabetic rats by measuring dimethylamine (DMA) formed from asymmetric dimethylarginine (ADMA): evaluation of the importance of S-nitrosothiols as inhibitors of DDAH activity in vitro and in vivo in humans.

Chobanyan K, Thum T, Suchy MT, Zhu B, Mitschke A, Gutzki FM, Beckmann B, Stichtenoth DO, Tsikas D.

J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Oct 15;858(1-2):32-41. Epub 2007 Aug 7.

PMID:
17825631
[PubMed - indexed for MEDLINE]
20.

Asymmetric dimethylarginine potentiates lung inflammation in a mouse model of allergic asthma.

Klein E, Weigel J, Buford MC, Holian A, Wells SM.

Am J Physiol Lung Cell Mol Physiol. 2010 Dec;299(6):L816-25. doi: 10.1152/ajplung.00188.2010. Epub 2010 Oct 1.

PMID:
20889675
[PubMed - indexed for MEDLINE]
Free PMC Article

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