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Results: 1 to 20 of 183

1.

Genetic association analysis of complex diseases incorporating intermediate phenotype information.

Li Y, Huang J, Amos CI.

PLoS One. 2012;7(10):e46612. doi: 10.1371/journal.pone.0046612. Epub 2012 Oct 19.

PMID:
23094028
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD.

Saccone NL, Culverhouse RC, Schwantes-An TH, Cannon DS, Chen X, Cichon S, Giegling I, Han S, Han Y, Keskitalo-Vuokko K, Kong X, Landi MT, Ma JZ, Short SE, Stephens SH, Stevens VL, Sun L, Wang Y, Wenzlaff AS, Aggen SH, Breslau N, Broderick P, Chatterjee N, Chen J, Heath AC, Heliövaara M, Hoft NR, Hunter DJ, Jensen MK, Martin NG, Montgomery GW, Niu T, Payne TJ, Peltonen L, Pergadia ML, Rice JP, Sherva R, Spitz MR, Sun J, Wang JC, Weiss RB, Wheeler W, Witt SH, Yang BZ, Caporaso NE, Ehringer MA, Eisen T, Gapstur SM, Gelernter J, Houlston R, Kaprio J, Kendler KS, Kraft P, Leppert MF, Li MD, Madden PA, Nöthen MM, Pillai S, Rietschel M, Rujescu D, Schwartz A, Amos CI, Bierut LJ.

PLoS Genet. 2010 Aug 5;6(8). pii: e1001053. doi: 10.1371/journal.pgen.1001053.

PMID:
20700436
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Nicotinic acetylcholine receptor region on chromosome 15q25 and lung cancer risk among African Americans: a case-control study.

Amos CI, Gorlov IP, Dong Q, Wu X, Zhang H, Lu EY, Scheet P, Greisinger AJ, Mills GB, Spitz MR.

J Natl Cancer Inst. 2010 Aug 4;102(15):1199-205. doi: 10.1093/jnci/djq232. Epub 2010 Jun 16.

PMID:
20554942
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Role of CHRNA5-A3 genetic Locus variants and developing drug for chronic obstructive pulmonary disease.

Lococo F, Cesario A, Petracca-Ciavarella L, Granone P, Russo P.

Curr Med Chem. 2012;19(34):5863-70.

PMID:
23061658
[PubMed - indexed for MEDLINE]
5.

Analysis of detailed phenotype profiles reveals CHRNA5-CHRNA3-CHRNB4 gene cluster association with several nicotine dependence traits.

Broms U, Wedenoja J, Largeau MR, Korhonen T, Pitkäniemi J, Keskitalo-Vuokko K, Häppölä A, Heikkilä KH, Heikkilä K, Ripatti S, Sarin AP, Salminen O, Paunio T, Pergadia ML, Madden PA, Kaprio J, Loukola A.

Nicotine Tob Res. 2012 Jun;14(6):720-33. doi: 10.1093/ntr/ntr283. Epub 2012 Jan 12.

PMID:
22241830
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Fine mapping of chromosome 15q25.1 lung cancer susceptibility in African-Americans.

Hansen HM, Xiao Y, Rice T, Bracci PM, Wrensch MR, Sison JD, Chang JS, Smirnov IV, Patoka J, Seldin MF, Quesenberry CP, Kelsey KT, Wiencke JK.

Hum Mol Genet. 2010 Sep 15;19(18):3652-61. doi: 10.1093/hmg/ddq268. Epub 2010 Jun 29.

PMID:
20587604
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

The CHRNA5-A3 region on chromosome 15q24-25.1 is a risk factor both for nicotine dependence and for lung cancer.

Spitz MR, Amos CI, Dong Q, Lin J, Wu X.

J Natl Cancer Inst. 2008 Nov 5;100(21):1552-6. doi: 10.1093/jnci/djn363. Epub 2008 Oct 28.

PMID:
18957677
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Variants located upstream of CHRNB4 on chromosome 15q25.1 are associated with age at onset of daily smoking and habitual smoking.

Kapoor M, Wang JC, Bertelsen S, Bucholz K, Budde JP, Hinrichs A, Agrawal A, Brooks A, Chorlian D, Dick D, Hesselbrock V, Foroud T, Kramer J, Kuperman S, Manz N, Nurnberger J Jr, Porjesz B, Rice J, Tischfield J, Xuei X, Schuckit M, Edenberg HJ, Bierut LJ, Goate AM.

PLoS One. 2012;7(3):e33513. doi: 10.1371/journal.pone.0033513. Epub 2012 Mar 16.

PMID:
22438940
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

The transforming growth factor-beta1 (TGFB1) gene is associated with chronic obstructive pulmonary disease (COPD).

Celedón JC, Lange C, Raby BA, Litonjua AA, Palmer LJ, DeMeo DL, Reilly JJ, Kwiatkowski DJ, Chapman HA, Laird N, Sylvia JS, Hernandez M, Speizer FE, Weiss ST, Silverman EK.

Hum Mol Genet. 2004 Aug 1;13(15):1649-56. Epub 2004 Jun 2.

PMID:
15175276
[PubMed - indexed for MEDLINE]
Free Article
10.

Mediating effects of smoking and chronic obstructive pulmonary disease on the relation between the CHRNA5-A3 genetic locus and lung cancer risk.

Wang J, Spitz MR, Amos CI, Wilkinson AV, Wu X, Shete S.

Cancer. 2010 Jul 15;116(14):3458-62. doi: 10.1002/cncr.25085.

PMID:
20564069
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Replication of lung cancer susceptibility loci at chromosomes 15q25, 5p15, and 6p21: a pooled analysis from the International Lung Cancer Consortium.

Truong T, Hung RJ, Amos CI, Wu X, Bickeböller H, Rosenberger A, Sauter W, Illig T, Wichmann HE, Risch A, Dienemann H, Kaaks R, Yang P, Jiang R, Wiencke JK, Wrensch M, Hansen H, Kelsey KT, Matsuo K, Tajima K, Schwartz AG, Wenzlaff A, Seow A, Ying C, Staratschek-Jox A, Nürnberg P, Stoelben E, Wolf J, Lazarus P, Muscat JE, Gallagher CJ, Zienolddiny S, Haugen A, van der Heijden HF, Kiemeney LA, Isla D, Mayordomo JI, Rafnar T, Stefansson K, Zhang ZF, Chang SC, Kim JH, Hong YC, Duell EJ, Andrew AS, Lejbkowicz F, Rennert G, Müller H, Brenner H, Le Marchand L, Benhamou S, Bouchardy C, Teare MD, Xue X, McLaughlin J, Liu G, McKay JD, Brennan P, Spitz MR.

J Natl Cancer Inst. 2010 Jul 7;102(13):959-71. doi: 10.1093/jnci/djq178. Epub 2010 Jun 14.

PMID:
20548021
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Genome-wide meta-analyses of smoking behaviors in African Americans.

David SP, Hamidovic A, Chen GK, Bergen AW, Wessel J, Kasberger JL, Brown WM, Petruzella S, Thacker EL, Kim Y, Nalls MA, Tranah GJ, Sung YJ, Ambrosone CB, Arnett D, Bandera EV, Becker DM, Becker L, Berndt SI, Bernstein L, Blot WJ, Broeckel U, Buxbaum SG, Caporaso N, Casey G, Chanock SJ, Deming SL, Diver WR, Eaton CB, Evans DS, Evans MK, Fornage M, Franceschini N, Harris TB, Henderson BE, Hernandez DG, Hitsman B, Hu JJ, Hunt SC, Ingles SA, John EM, Kittles R, Kolb S, Kolonel LN, Le Marchand L, Liu Y, Lohman KK, McKnight B, Millikan RC, Murphy A, Neslund-Dudas C, Nyante S, Press M, Psaty BM, Rao DC, Redline S, Rodriguez-Gil JL, Rybicki BA, Signorello LB, Singleton AB, Smoller J, Snively B, Spring B, Stanford JL, Strom SS, Swan GE, Taylor KD, Thun MJ, Wilson AF, Witte JS, Yamamura Y, Yanek LR, Yu K, Zheng W, Ziegler RG, Zonderman AB, Jorgenson E, Haiman CA, Furberg H.

Transl Psychiatry. 2012 May 22;2:e119. doi: 10.1038/tp.2012.41.

PMID:
22832964
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Racial differences in the association between SNPs on 15q25.1, smoking behavior, and risk of non-small cell lung cancer.

Schwartz AG, Cote ML, Wenzlaff AS, Land S, Amos CI.

J Thorac Oncol. 2009 Oct;4(10):1195-201. doi: 10.1097/JTO.0b013e3181b244ef.

PMID:
19641473
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Relationship between CYP2A6 and CHRNA5-CHRNA3-CHRNB4 variation and smoking behaviors and lung cancer risk.

Wassenaar CA, Dong Q, Wei Q, Amos CI, Spitz MR, Tyndale RF.

J Natl Cancer Inst. 2011 Sep 7;103(17):1342-6. doi: 10.1093/jnci/djr237. Epub 2011 Jul 11.

PMID:
21747048
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Chromosome 15q25 (CHRNA3-CHRNA5) variation impacts indirectly on lung cancer risk.

Wang Y, Broderick P, Matakidou A, Eisen T, Houlston RS.

PLoS One. 2011 Apr 29;6(4):e19085. doi: 10.1371/journal.pone.0019085.

PMID:
21559498
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking.

Stephens SH, Hartz SM, Hoft NR, Saccone NL, Corley RC, Hewitt JK, Hopfer CJ, Breslau N, Coon H, Chen X, Ducci F, Dueker N, Franceschini N, Frank J, Han Y, Hansel NN, Jiang C, Korhonen T, Lind PA, Liu J, Lyytikäinen LP, Michel M, Shaffer JR, Short SE, Sun J, Teumer A, Thompson JR, Vogelzangs N, Vink JM, Wenzlaff A, Wheeler W, Yang BZ, Aggen SH, Balmforth AJ, Baumeister SE, Beaty TH, Benjamin DJ, Bergen AW, Broms U, Cesarini D, Chatterjee N, Chen J, Cheng YC, Cichon S, Couper D, Cucca F, Dick D, Foroud T, Furberg H, Giegling I, Gillespie NA, Gu F, Hall AS, Hällfors J, Han S, Hartmann AM, Heikkilä K, Hickie IB, Hottenga JJ, Jousilahti P, Kaakinen M, Kähönen M, Koellinger PD, Kittner S, Konte B, Landi MT, Laatikainen T, Leppert M, Levy SM, Mathias RA, McNeil DW, Medland SE, Montgomery GW, Murray T, Nauck M, North KE, Paré PD, Pergadia M, Ruczinski I, Salomaa V, Viikari J, Willemsen G, Barnes KC, Boerwinkle E, Boomsma DI, Caporaso N, Edenberg HJ, Francks C, Gelernter J, Grabe HJ, Hops H, Jarvelin MR, Johannesson M, Kendler KS, Lehtimäki T, Magnusson PK, Marazita ML, Marchini J, Mitchell BD, Nöthen MM, Penninx BW, Raitakari O, Rietschel M, Rujescu D, Samani NJ, Schwartz AG, Shete S, Spitz M, Swan GE, Völzke H, Veijola J, Wei Q, Amos C, Cannon DS, Grucza R, Hatsukami D, Heath A, Johnson EO, Kaprio J, Madden P, Martin NG, Stevens VL, Weiss RB, Kraft P, Bierut LJ, Ehringer MA.

Genet Epidemiol. 2013 Dec;37(8):846-59. doi: 10.1002/gepi.21760. Epub 2013 Nov 1.

PMID:
24186853
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Testing Hardy-Weinberg proportions in a frequency-matched case-control genetic association study.

Wang J, Shete S.

PLoS One. 2011;6(11):e27642. doi: 10.1371/journal.pone.0027642. Epub 2011 Nov 14.

PMID:
22110703
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Genetic polymorphisms in 15q25 and 19q13 loci, cotinine levels, and risk of lung cancer in EPIC.

Timofeeva MN, McKay JD, Smith GD, Johansson M, Byrnes GB, Chabrier A, Relton C, Ueland PM, Vollset SE, Midttun Ø, Nygård O, Slimani N, Romieu I, Clavel-Chapelon F, Boutron-Ruault MC, Fagherazzi G, Kaaks R, Teucher B, Boeing H, Weikert C, Bueno-de-Mesquita HB, van Gils C, Peeters PH, Agudo A, Barricarte A, Huerta JM, Rodríguez L, Sánchez MJ, Larrañaga N, Khaw KT, Wareham N, Allen NE, Travis RC, Gallo V, Norat T, Krogh V, Masala G, Panico S, Sacerdote C, Tumino R, Trichopoulou A, Lagiou P, Trichopoulos D, Rasmuson T, Hallmans G, Riboli E, Vineis P, Brennan P.

Cancer Epidemiol Biomarkers Prev. 2011 Oct;20(10):2250-61. doi: 10.1158/1055-9965.EPI-11-0496. Epub 2011 Aug 23.

PMID:
21862624
[PubMed - indexed for MEDLINE]
Free Article
19.

CHRNA3/5, IREB2, and ADCY2 are associated with severe chronic obstructive pulmonary disease in Poland.

Hardin M, Zielinski J, Wan ES, Hersh CP, Castaldi PJ, Schwinder E, Hawrylkiewicz I, Sliwinski P, Cho MH, Silverman EK.

Am J Respir Cell Mol Biol. 2012 Aug;47(2):203-8. doi: 10.1165/rcmb.2012-0011OC. Epub 2012 Mar 29.

PMID:
22461431
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Susceptibility locus for lung cancer at 15q25.1 is not associated with risk of pancreatic cancer.

Chen J, Wu X, Pande M, Amos CI, Killary AM, Sen S, Frazier ML.

Pancreas. 2011 Aug;40(6):872-5. doi: 10.1097/MPA.0b013e318219dafe.

PMID:
21697764
[PubMed - indexed for MEDLINE]
Free PMC Article

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