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Correlation analyses of clinical and molecular findings identify candidate biological pathways in systemic juvenile idiopathic arthritis.

Ling XB, Macaubas C, Alexander HC, Wen Q, Chen E, Peng S, Sun Y, Deshpande C, Pan KH, Lin R, Lih CJ, Chang SY, Lee T, Sandborg C, Begovich AB, Cohen SN, Mellins ED.

BMC Med. 2012 Oct 23;10:125. doi: 10.1186/1741-7015-10-125.


Immature cell populations and an erythropoiesis gene-expression signature in systemic juvenile idiopathic arthritis: implications for pathogenesis.

Hinze CH, Fall N, Thornton S, Mo JQ, Aronow BJ, Layh-Schmitt G, Griffin TA, Thompson SD, Colbert RA, Glass DN, Barnes MG, Grom AA.

Arthritis Res Ther. 2010;12(3):R123. doi: 10.1186/ar3061. Epub 2010 Jun 24.


Subtype-specific peripheral blood gene expression profiles in recent-onset juvenile idiopathic arthritis.

Barnes MG, Grom AA, Thompson SD, Griffin TA, Pavlidis P, Itert L, Fall N, Sowders DP, Hinze CH, Aronow BJ, Luyrink LK, Srivastava S, Ilowite NT, Gottlieb BS, Olson JC, Sherry DD, Glass DN, Colbert RA.

Arthritis Rheum. 2009 Jul;60(7):2102-12. doi: 10.1002/art.24601.


Follistatin-like protein 1 and the ferritin/erythrocyte sedimentation rate ratio are potential biomarkers for dysregulated gene expression and macrophage activation syndrome in systemic juvenile idiopathic arthritis.

Gorelik M, Fall N, Altaye M, Barnes MG, Thompson SD, Grom AA, Hirsch R.

J Rheumatol. 2013 Jul;40(7):1191-9. doi: 10.3899/jrheum.121131. Epub 2013 May 15.


Gene expression signatures in polyarticular juvenile idiopathic arthritis demonstrate disease heterogeneity and offer a molecular classification of disease subsets.

Griffin TA, Barnes MG, Ilowite NT, Olson JC, Sherry DD, Gottlieb BS, Aronow BJ, Pavlidis P, Hinze CH, Thornton S, Thompson SD, Grom AA, Colbert RA, Glass DN.

Arthritis Rheum. 2009 Jul;60(7):2113-23. doi: 10.1002/art.24534.


Distribution of circulating cells in systemic juvenile idiopathic arthritis across disease activity states.

Macaubas C, Nguyen K, Deshpande C, Phillips C, Peck A, Lee T, Park JL, Sandborg C, Mellins ED.

Clin Immunol. 2010 Feb;134(2):206-16. doi: 10.1016/j.clim.2009.09.010. Epub 2009 Oct 29.


Abnormal expression of the genes involved in cytokine networks and mitochondrial function in systemic juvenile idiopathic arthritis identified by DNA microarray analysis.

Ishikawa S, Mima T, Aoki C, Yoshio-Hoshino N, Adachi Y, Imagawa T, Mori M, Tomiita M, Iwata N, Murata T, Miyoshi M, Takei S, Aihara Y, Yokota S, Matsubara K, Nishimoto N.

Ann Rheum Dis. 2009 Feb;68(2):264-72. doi: 10.1136/ard.2007.079533. Epub 2008 Apr 3.


Plasma profiles in active systemic juvenile idiopathic arthritis: Biomarkers and biological implications.

Ling XB, Park JL, Carroll T, Nguyen KD, Lau K, Macaubas C, Chen E, Lee T, Sandborg C, Milojevic D, Kanegaye JT, Gao S, Burns J, Schilling J, Mellins ED.

Proteomics. 2010 Dec;10(24):4415-30. doi: 10.1002/pmic.201000298. Epub 2010 Nov 23.


Candidate early predictors for progression to joint damage in systemic juvenile idiopathic arthritis.

Sandborg C, Holmes TH, Lee T, Biederman K, Bloch DA, Emery H, McCurdy D, Mellins ED.

J Rheumatol. 2006 Nov;33(11):2322-9. Epub 2006 Sep 1.


Global damage in systemic juvenile idiopathic arthritis: preliminary early predictors.

Russo RA, Katsicas MM.

J Rheumatol. 2008 Jun;35(6):1151-6. Epub 2008 Apr 1.


Mesenchymal stromal cells isolated from children with systemic juvenile idiopathic arthritis suppress innate and adaptive immune responses.

Calkoen FG, Brinkman DM, Vervat C, van Ostaijen-Ten Dam MM, Ten Cate R, van Tol MJ, Ball LM.

Cytotherapy. 2013 Mar;15(3):280-91. doi: 10.1016/j.jcyt.2012.10.017. Epub 2013 Jan 9.


Th17 transcription factor RORC2 is inversely correlated with FOXP3 expression in the joints of children with juvenile idiopathic arthritis.

Olivito B, Simonini G, Ciullini S, Moriondo M, Betti L, Gambineri E, Cantarini L, De Martino M, Azzari C, Cimaz R.

J Rheumatol. 2009 Sep;36(9):2017-24. doi: 10.3899/jrheum.090066. Epub 2009 Jul 31.


Th1 and Th17 cell subpopulations are enriched in the peripheral blood of patients with systemic juvenile idiopathic arthritis.

Omoyinmi E, Hamaoui R, Pesenacker A, Nistala K, Moncrieffe H, Ursu S, Wedderburn LR, Woo P.

Rheumatology (Oxford). 2012 Oct;51(10):1881-6. Epub 2012 Jul 5.


Using the Juvenile Arthritis Disease Activity Score based on erythrocyte sedimentation rate or C-reactive protein level: results from the Portuguese register.

Mourão AF, Santos MJ, Melo-Gomes J, Martins FM, Costa JA, Ramos F, Brito I, Duarte C, Figueira R, Figueiredo G, Furtado C, Lopes A, Oliveira M, Rodrigues A, Salgado M, Sousa M, Branco JC, Fonseca JE, Canhão H.

Arthritis Care Res (Hoboken). 2014 Apr;66(4):585-91. doi: 10.1002/acr.22215.


Gene expression in juvenile arthritis and spondyloarthropathy: pro-angiogenic ELR+ chemokine genes relate to course of arthritis.

Barnes MG, Aronow BJ, Luyrink LK, Moroldo MB, Pavlidis P, Passo MH, Grom AA, Hirsch R, Giannini EH, Colbert RA, Glass DN, Thompson SD.

Rheumatology (Oxford). 2004 Aug;43(8):973-9. Epub 2004 May 18. Erratum in: Rheumatology (Oxford). 2004 Oct;43(10):1320.


Osteoblastogenesis from synovial fluid-derived cells is related to the type and severity of juvenile idiopathic arthritis.

Lazić E, Jelušić M, Grčević D, Marušić A, Kovačić N.

Arthritis Res Ther. 2012 Jun 12;14(3):R139. doi: 10.1186/ar3872.


Levels of serum matrix metalloproteinase-3 correlate with disease activity in the enthesitis-related arthritis category of juvenile idiopathic arthritis.

Viswanath V, Myles A, Dayal R, Aggarwal A.

J Rheumatol. 2011 Nov;38(11):2482-7. doi: 10.3899/jrheum.110352. Epub 2011 Sep 1.


Serum amyloid A circulating levels and disease activity in patients with juvenile idiopathic arthritis.

Cantarini L, Giani T, Fioravanti A, Iacoponi F, Simonini G, Pagnini I, Spreafico A, Chellini F, Galeazzi M, Cimaz R.

Yonsei Med J. 2012 Sep;53(5):1045-8. doi: 10.3349/ymj.2012.53.5.1045.

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