Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 107

1.

Embedding siRNA sequences targeting apolipoprotein B100 in shRNA and miRNA scaffolds results in differential processing and in vivo efficacy.

Maczuga P, Lubelski J, van Logtenstein R, Borel F, Blits B, Fakkert E, Costessi A, Butler D, van Deventer S, Petry H, Koornneef A, Konstantinova P.

Mol Ther. 2013 Jan;21(1):217-27. doi: 10.1038/mt.2012.160. Epub 2012 Oct 23.

PMID:
23089734
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Therapeutic expression of hairpins targeting apolipoprotein B100 induces phenotypic and transcriptome changes in murine liver.

Maczuga P, Verheij J, van der Loos C, van Logtenstein R, Hooijer G, Martier R, Borel F, Lubelski J, Koornneef A, Blits B, van Deventer S, Petry H, Konstantinova P.

Gene Ther. 2014 Jan;21(1):60-70. doi: 10.1038/gt.2013.58. Epub 2013 Oct 24.

PMID:
24152580
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Apolipoprotein B knockdown by AAV-delivered shRNA lowers plasma cholesterol in mice.

Koornneef A, Maczuga P, van Logtenstein R, Borel F, Blits B, Ritsema T, van Deventer S, Petry H, Konstantinova P.

Mol Ther. 2011 Apr;19(4):731-40. doi: 10.1038/mt.2011.6. Epub 2011 Feb 8.

PMID:
21304496
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Optimization and comparison of knockdown efficacy between polymerase II expressed shRNA and artificial miRNA targeting luciferase and Apolipoprotein B100.

Maczuga P, Koornneef A, Borel F, Petry H, van Deventer S, Ritsema T, Konstantinova P.

BMC Biotechnol. 2012 Jul 24;12:42. doi: 10.1186/1472-6750-12-42.

PMID:
22827812
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways.

Grimm D, Streetz KL, Jopling CL, Storm TA, Pandey K, Davis CR, Marion P, Salazar F, Kay MA.

Nature. 2006 May 25;441(7092):537-41.

PMID:
16724069
[PubMed - indexed for MEDLINE]
6.

A quick and efficient approach for gene silencing by using triple putative microRNA-based short hairpin RNAs.

Shan ZX, Lin QX, Yang M, Deng CY, Kuang SJ, Zhou ZL, Xiao DZ, Liu XY, Lin SG, Yu XY.

Mol Cell Biochem. 2009 Mar;323(1-2):81-9. doi: 10.1007/s11010-008-9966-3. Epub 2008 Nov 27.

PMID:
19037714
[PubMed - indexed for MEDLINE]
7.

Expression of shRNA from a tissue-specific pol II promoter is an effective and safe RNAi therapeutic.

Giering JC, Grimm D, Storm TA, Kay MA.

Mol Ther. 2008 Sep;16(9):1630-6. doi: 10.1038/mt.2008.144. Epub 2008 Jul 29.

PMID:
18665161
[PubMed - indexed for MEDLINE]
8.

Enhanced gene silencing of HIV-1 specific siRNA using microRNA designed hairpins.

Boden D, Pusch O, Silbermann R, Lee F, Tucker L, Ramratnam B.

Nucleic Acids Res. 2004 Feb 13;32(3):1154-8. Print 2004.

PMID:
14966264
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

RNA interference inhibitors of hepatitis B virus.

McCaffrey AP.

Ann N Y Acad Sci. 2009 Sep;1175:15-23. doi: 10.1111/j.1749-6632.2009.04974.x.

PMID:
19796073
[PubMed - indexed for MEDLINE]
10.

Inhibition of hepatitis C virus replication using adeno-associated virus vector delivery of an exogenous anti-hepatitis C virus microRNA cluster.

Yang X, Haurigot V, Zhou S, Luo G, Couto LB.

Hepatology. 2010 Dec;52(6):1877-87. doi: 10.1002/hep.23908. Epub 2010 Oct 7.

PMID:
20931557
[PubMed - indexed for MEDLINE]
11.

A facile lentiviral vector system for expression of doxycycline-inducible shRNAs: knockdown of the pre-miRNA processing enzyme Drosha.

Aagaard L, Amarzguioui M, Sun G, Santos LC, Ehsani A, Prydz H, Rossi JJ.

Mol Ther. 2007 May;15(5):938-45. Epub 2007 Feb 20.

PMID:
17311008
[PubMed - indexed for MEDLINE]
12.

A direct comparison of strategies for combinatorial RNA interference.

Lambeth LS, Van Hateren NJ, Wilson SA, Nair V.

BMC Mol Biol. 2010 Oct 11;11:77. doi: 10.1186/1471-2199-11-77.

PMID:
20937117
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Construction of simple and efficient DNA vector-based short hairpin RNA expression systems for specific gene silencing in mammalian cells.

Cheng TL, Chang WT.

Methods Mol Biol. 2007;408:223-41. doi: 10.1007/978-1-59745-547-3_13.

PMID:
18314586
[PubMed - indexed for MEDLINE]
14.

Optimization of a microRNA expression vector for function analysis of microRNA.

Furukawa N, Sakurai F, Katayama K, Seki N, Kawabata K, Mizuguchi H.

J Control Release. 2011 Feb 28;150(1):94-101. doi: 10.1016/j.jconrel.2010.12.001. Epub 2010 Dec 10.

PMID:
21146569
[PubMed - indexed for MEDLINE]
15.

A miR-21 hairpin structure-based gene knockdown vector.

Yue J, Sheng Y, Ren A, Penmatsa S.

Biochem Biophys Res Commun. 2010 Apr 9;394(3):667-72. doi: 10.1016/j.bbrc.2010.03.047. Epub 2010 Mar 11.

PMID:
20226761
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Primer extension-based method for the generation of a siRNA/miRNA expression vector.

Gou D, Zhang H, Baviskar PS, Liu L.

Physiol Genomics. 2007 Nov 14;31(3):554-62. Epub 2007 Sep 5.

PMID:
17804605
[PubMed - indexed for MEDLINE]
Free Article
17.

Expression of RNA interference triggers from an oncolytic herpes simplex virus results in specific silencing in tumour cells in vitro and tumours in vivo.

Anesti AM, Simpson GR, Price T, Pandha HS, Coffin RS.

BMC Cancer. 2010 Sep 13;10:486. doi: 10.1186/1471-2407-10-486.

PMID:
20836854
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

DNA vector-based RNA interference to study gene function in cancer.

Stovall DB, Wan M, Zhang Q, Dubey P, Sui G.

J Vis Exp. 2012 Jun 4;(64):e4129. doi: 10.3791/4129.

PMID:
22710444
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Adeno-associated virus-delivered polycistronic microRNA-clusters for knockdown of vascular endothelial growth factor in vivo.

Pihlmann M, Askou AL, Aagaard L, Bruun GH, Svalgaard JD, Holm-Nielsen MH, Dagnaes-Hansen F, Bek T, Mikkelsen JG, Jensen TG, Corydon TJ.

J Gene Med. 2012 May;14(5):328-38. doi: 10.1002/jgm.2623.

PMID:
22438271
[PubMed - indexed for MEDLINE]
20.

Constitutive expression of short hairpin RNA in vivo triggers buildup of mature hairpin molecules.

Ahn M, Witting SR, Ruiz R, Saxena R, Morral N.

Hum Gene Ther. 2011 Dec;22(12):1483-97. doi: 10.1089/hum.2010.234. Epub 2011 Oct 4.

PMID:
21780944
[PubMed - indexed for MEDLINE]
Free PMC Article

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk